Peptide Decoding
Two peptide vials side by side on a dark surface
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Commonly confused peptides

Long-form breakdowns of the pairs people confuse most, traced to primary sources.

Growth hormone

HGH vs Sermorelin

Distributing HGH for anti-aging is a federal felony carrying five years. Sermorelin lost to it commercially in 2008 and can still be legally compounded.

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Muscle

IGF-1 LR3 vs IGF-1 DES

Neither has a single published human trial, and sources give LR3's half-life as anywhere from 6 to 30 hours. There is an FDA approved IGF-1, and it is neither of these.

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Healing and recovery

Thymosin Alpha-1 vs LL-37

One is approved in 35 countries and its largest trial found nothing. The other has never been injected in a published study.

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Metabolic and weight loss

Cagrilintide vs Semaglutide

Both were tested in the same trial, in the same people, over the same 68 weeks. Semaglutide won on weight, and the combination beat both while coming in below their sum.

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Metabolic and weight loss

Retatrutide vs Tirzepatide

Retatrutide's 28.3 percent is being set against tirzepatide's 22.5 percent. Different trials, different lengths, and one of the numbers comes from a press release.

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Sexual and hormonal

PT-141 vs Kisspeptin

Both are sold for sex. One works on desire and is FDA approved, the other works on hormones and stops working within two weeks.

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Longevity

MOTS-c vs SS-31

One has an FDA approval and a failed Phase 3. The other has never been given to a person in a published study.

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Growth hormone

Tesamorelin vs CJC-1295

Two GHRH analogs tested for the same condition. One completed two Phase 3 trials and got approved. The other's Phase 2 was halted in 2006 and never restarted.

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Skin and repair

Melanotan I vs Melanotan II

Not two versions of one compound. One is an FDA approved implant for a rare disease, the other is approved nowhere and warned against by four regulators.

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Longevity

Epitalon vs MOTS-c

Two longevity peptides with no published human trial between them. Epitalon's famous human data belongs to a bovine extract, and MOTS-c is something your body already makes.

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Longevity

Glutathione vs NAD+

Both are sold as injections. NAD+ cannot enter cells intact, and a six month trial found oral glutathione raising body stores the injection is meant to fix.

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Cognitive and mood

Semax vs Selank

Same Russian lab, same seven amino acids, built for different problems: Semax for alertness, Selank for anxiety.

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Skin and repair

GHK-Cu vs Matrixyl

Two topical skin peptides with very different evidence: one carries copper, one carries a fat tail, and the most sold version of Matrixyl is built on the same tripeptide as GHK-Cu.

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Healing and recovery

BPC-157 vs TB-500

Both are sold for tendon and muscle repair. BPC-157's human trials were enemas for ulcerative colitis, and TB-500's trials did not even use TB-500.

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Growth hormone

CJC-1295 with DAC vs without DAC

One name, two drugs: one has a measured half-life and three published human trials, the other has never been tested in a person.

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Growth hormone

Ipamorelin vs CJC-1295

They act on different receptors and are usually sold in the same vial. Each has human trials; the combination everyone buys has none.

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Growth hormone

MK-677 vs Ipamorelin

Same receptor, a pill against an injection. MK-677 has far more human data, and that is exactly why we know more about what is wrong with it.

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Healing and recovery

KLOW vs GLOW

These are not two products. One contains the other: KLOW is GLOW plus KPV, and neither blend has ever been tested as a blend.

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Growth hormone

Sermorelin vs Ipamorelin

Two growth hormone peptides sold side by side. One was an approved drug and can still be compounded on prescription. The other was voted down in October 2024.

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19 published

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