Imunofan is a thymopentin analog. Thymopentin is a thymus hormone fragment.
| Comparison | Imunofan Immunofan · Imunofan | Thymopentin (TP-5) Thymopentin · TP-5 |
|---|---|---|
| How it works | How it works Imunofan starts from thymopentin and changes the ends. The claim attached to it is about timing, and it is worth reading with care. | How it works Your thymus trains immune cells when you are young and shrinks as you age. This peptide is the part of a thymus hormone that does the training signal. |
| What it is | A Russian rework of thymopentin, with one amino acid added at each end. | Five amino acids that carry the whole activity of a thymus hormone. |
| Status | Research only | In clinical useApproved abroad, not FDA approved |
| Typical dose | 0.05 mg per dose | 50 mg per dose |
| How often | Every other day, in courses | 3x per week |
| Stays active | Not established | About 90 seconds |
| Dose comes from | Clinical guideline | Clinical guideline |
| Cycled? | Given every other day in courses of about 10 doses Clinical guideline | Given in courses, usually a few weeks at a time Clinical guideline |
| What it does | ||
| Drug class | Thymopentin analog | Thymus hormone fragment |
| Used for | An injection used in Russia for a weakened immune system and long-running infections. | An immune-support injection, approved and used in China for a weakened immune system. |
| Receptors hit | — | — |
| Numbers | ||
| Full dose line | 50 mcg per dose | 50 mg per dose |
| Why that cycle | The course pattern comes from Russian prescribing rather than a trial comparing schedules. | Prescribing practice abroad uses courses rather than continuous use. No trial has compared course lengths. |
| Weight / effect | Not measured in a trial | Not measured in a trial |
| Chain length | 6 residues | 5 residues |
| Common vial | — | 10 mg |
| Before you start | ||
| Route | Under the skin or into muscle | Under the skin or into muscle |
| Do not use if | Pregnancy, particularly with a history of pre-eclampsia Known allergy to it Taking medicine that deliberately suppresses the immune system | Known allergy to it Pregnancy Taking medicine that deliberately suppresses the immune system, such as after a transplant |
What separates them
Legal standing. Thymopentin is approved or in established clinical use. Imunofan is research-only, meaning no regulator has assessed it for use in people.
What doesn't differ: They are both taken the same way (under the skin or into muscle) and aimed at the same thing (immune support). Neither has a measured effect size from a published trial, so there is no number to rank them on.
What people actually report
Imunofan
- Registered in Russia, never approved in the US or Europe.
- Nearly all published evidence is Russian and has not been repeated elsewhere.
- Signs of an allergic reaction such as face or throat swelling, hives, or trouble breathing
- A spreading rash
Thymopentin (TP-5)
- Approved and used in China, but never approved in the US.
- Most human data comes from studies published outside the US and Europe.
- Signs of an allergic reaction such as face or throat swelling, hives, or trouble breathing
- A spreading rash
Side effects are what users and trials report most often, not a complete list. Anything sudden, spreading, or breathing-related is an emergency regardless of which compound caused it.
People also compare
This comparison does not cover cost, long-term safety, or how you personally will respond. Effect figures come from separate trials in different populations and are not always directly comparable to each other. Nothing here is medical advice or a recommendation to use any of these. Talk to a clinician about your own situation.