Healing and recovery

PDA (pentadeca arginate) is a more stable, arginate-salt cousin of BPC-157. In plain terms: it aims to do the same repair job, healing gut, tendon, and muscle, while lasting longer in the body. It is very new.

GLOW is a pre-mixed blend of three peptides: GHK-Cu for skin, plus BPC-157 and TB-500 for tissue repair. In plain terms: it bundles a skin-and-healing stack into one injection.

KLOW is the GLOW blend (GHK-Cu, BPC-157, TB-500) with KPV added for extra anti-inflammatory effect. In plain terms: it is an all-in-one recovery-and-skin stack in a single shot.

KPV is a tripeptide, the three-amino-acid tail (lysine-proline-valine) of the hormone alpha-MSH, minus the part that causes tanning. In plain terms: it carries alpha-MSH's anti-inflammatory action to calm the gut and skin without darkening skin. There are no human trials yet.

ARA-290 (cibinetide) is an 11-amino-acid peptide carved from the tissue-protective part of erythropoietin (EPO), the hormone that makes red blood cells. In plain terms: it keeps only EPO's healing, anti-inflammatory side, switching on a 'repair receptor' in injured nerves and tissue without thickening the blood. It reached real human trials for nerve pain.

VIP (vasoactive intestinal peptide) is a natural 28-amino-acid signaling peptide found in the gut, lungs, and nerves. In plain terms: it relaxes blood vessels and airways and calms the immune system, which is why a nasal-spray form is used to try to quiet chronic inflammation, though it can lower blood pressure.

Larazotide is an 8-amino-acid peptide that tightens the junctions between the cells lining your gut. In plain terms: it works locally in the intestine to seal a 'leaky' gut barrier and has been studied mainly for celiac disease. It is not absorbed into the body.

Pentosan polysulfate is a semi-synthetic sugar-based molecule, not a peptide, that acts like the natural lubricants in joints and the bladder lining. In plain terms: it coats and calms irritated tissue, used for arthritis and painful bladder. It is a prescription drug for some uses.

Cerebrolysin is a mixture of small peptides and amino acids extracted from pig brain tissue, rich in nerve-growth signals. In plain terms: injected in cycles, it feeds and protects brain cells, and it has the strongest human evidence in this group for stroke and dementia recovery.

Cortagen is a short peptide 'bioregulator' from the Russian Khavinson family, based on a brain-tissue peptide. In plain terms: it is taken in courses for nerve and tissue recovery, but there is very little real human research behind it.

Cartalax is a 3-amino-acid 'bioregulator' from the Russian Khavinson family. In plain terms: it is marketed for cartilage and joint health, but there is very little real human research behind it.

Ovagen is a short peptide 'bioregulator' from the Russian Khavinson family. In plain terms: it is marketed for liver and digestive support, but there is very little real human research behind it.

Chonluten is a 3-amino-acid 'bioregulator' from the Russian Khavinson family. In plain terms: it is marketed for lung and gut-lining support, but there is very little real human research behind it.

Cerluten is a peptide 'bioregulator' from the Russian Khavinson family, drawn from nerve tissue. In plain terms: it is marketed for brain and nervous-system support, but there is very little real human research behind it.

Sigumir is a peptide 'bioregulator' from the Russian Khavinson family, drawn from cartilage. In plain terms: it is marketed for bone, joint, and cartilage health, but there is very little real human research behind it.

BPC-157 + TB-500 is a pre-mixed blend of two repair peptides: BPC-157 and TB-500. In plain terms: it puts the two most popular healing compounds into a single injection. The nickname Wolverine is a community name borrowed from the comic book character. No company owns it, and no two vendors have to agree on what goes in the vial.

Teduglutide is a copy of GLP-2, a gut hormone that tells the lining of the intestine to grow and absorb more. In plain terms: it helps people whose intestine is too short to absorb enough food, so they need fewer hours hooked up to intravenous feeding. It is the only approved GLP-2 drug, and it is worth knowing about for a second reason: sellers use the name GLP-2 for tirzepatide, which is a different molecule with a different job.

Teriparatide is the working part of parathyroid hormone, the hormone that manages calcium in your body. Most osteoporosis drugs slow bone from breaking down. This one does the opposite job: it tells the body to build new bone. In plain terms: it is the drug used when bones are weak enough that slowing the damage is not enough.

Livagen is a 4-amino-acid 'bioregulator' from the Russian Khavinson family. In plain terms: it is marketed for liver support and how tightly DNA is packed in liver cells, but there is very little real human research behind it.

Vesilute is a 2-amino-acid 'bioregulator' from the Russian Khavinson family. In plain terms: it is marketed for bladder lining support, but there is very little real human research behind it.

B7-33 is a 26 amino acid peptide taken from the B-chain of human relaxin-2. Relaxin itself is a two-chain hormone held together by three disulfide bonds, which makes it difficult and expensive to manufacture. B7-33 was designed as a simpler single-chain version that keeps the anti-fibrotic activity.

Retinalamin is a polypeptide extract taken from the retinal tissue of cattle, developed in Russia and used there in eye clinics. It belongs to the same family of tissue extracts as Cortexin, which is made from brain cortex.

Coremend is a vendor name for a three-peptide vial holding TB-500, BPC-157 and KPV. In plain terms: it is the Wolverine pairing with an anti-inflammatory tripeptide added, and it sits one component short of KLOW.

Thymosin beta-15 is a relative of the thymosin beta-4 that TB-500 comes from. In plain terms: it is sold as another repair peptide, and the published work on it is about how aggressively prostate tumours spread.

Abaloparatide is a bone-building drug approved for osteoporosis. In plain terms: like teriparatide it tells the body to build new bone rather than just slowing the loss, and it is based on a different parent hormone.

Calcitonin is a hormone that lowers blood calcium and slows bone breakdown. In plain terms: the salmon version is more potent in humans than our own, and it is approved for osteoporosis and Paget's disease while being the least effective drug in that space.

Ac-SDKP is N-acetyl-Ser-Asp-Lys-Pro, an endogenous tetrapeptide cut from thymosin beta-4 by meprin-alpha and prolyl oligopeptidase, with antifibrotic and anti-inflammatory activity in animal models. In plain terms: it is the first four residues of TB-500, and the body already makes it on its own.

Regeno is a three-peptide vial combining BPC-157, TB-500 and Cartalax, the Khavinson tripeptide AED, typically at 10 mg of each in a 30 mg vial. In plain terms: it is the usual two healing peptides with a third one aimed at cartilage.