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Decoding

VIP (Vasoactive Intestinal Peptide)_

Also known as vasoactive intestinal peptide, aviptadil

A nasal-spray peptide used to calm chronic inflammation and immune problems.

Immune & inflammationNeuropeptideResearch only
Common vial size5 mg
Dose0.05 mg per dose
FrequencySeveral daily
RouteNasal spray
StatusResearch only
CycledNo established schedule

Common vial size is what vendors typically sell, not a recommendation. Enter your own vial in the calculator.

01

What is VIP (Vasoactive Intestinal Peptide)?

Plain language first. The technical label stays, but it never stands alone.

Overview

VIP (vasoactive intestinal peptide) is a natural 28-amino-acid signaling peptide found in the gut, lungs, and nerves. In plain terms: it relaxes blood vessels and airways and calms the immune system, which is why a nasal-spray form is used to try to quiet chronic inflammation, though it can lower blood pressure.

What it's used for

A nasal-spray peptide used to calm long-term inflammation and immune problems, popular in mold-illness protocols.

02

How does VIP (Vasoactive Intestinal Peptide) work?

What it does in the body, and where.

VIP is a 28-amino-acid signalling peptide your gut, lungs, and nerves already produce. The nasal form is used off-label for chronic inflammatory conditions.

  1. 01
    It relaxes blood vessels and airways
    The 'vasoactive' in the name, and its original identified function.
  2. 02
    It calms immune signalling
    Shifting immune cells away from an inflammatory state, which is the basis for its use in chronic inflammatory response syndrome.
  3. 03
    The nasal route is deliberate
    VIP is destroyed almost immediately in the bloodstream, so it is sprayed rather than injected.
  4. 04
    Its main use is off-label and contested
    The mould-illness protocols it appears in are not accepted by mainstream medicine, and the peptide's evidence should not be confused with the protocol's.
Where it acts
LungsGut

Where this compound is thought to act.

03

What else is it used for?

Each use below carries its own evidence level. Approved means regulators have cleared it for that purpose. Investigational means it is in trials. Early research means it is being studied and is not established.

  • Sarcoidosis and lung inflammationInvestigational
  • Chronic inflammatory response syndrome and mould illness, which is the main reason people seek it outResearch only
  • Severe COVID lung failure, where a large trial found no benefitInvestigational
04

How much, and do you cycle it?

The range, and whether you take breaks.

0.05 mg per dose, several daily. No established scheduleNo range

No published study has established how long to take this or whether a break is needed. Schedules quoted online come from vendors and forums, and different sources disagree.

Compare cycling across compounds →

05

How do I dose and price it?

Enter your vial and your dose. Pick a mix. We show the draw and the cost.

The vial holds a fixed amount of drug. Adding more water does not make more drug, it just spreads it thinner, so you draw a bigger number on the syringe for the same dose.

VIP (Vasoactive Intestinal Peptide) is not injected

It is taken nasal spray.

Cost per month
Cost per dose
Typical dose
50 mcg–50 mcg / doseCommunity practice
No published human study establishes this dose. It comes from vendor and community practice, and several compounds in this group share suspiciously identical round numbers across retailer sites.
06

How do you store it?

Before mixing, and after.

Fridge after opening. Use within about 30 days.

Store sealed VIP (Vasoactive Intestinal Peptide) in the fridge. Once opened, keep it upright in the fridge and plan to finish it inside roughly 30 days. Keep it out of light and do not freeze the liquid.

07

What are the side effects and cautions?

Known cautions and warnings for this compound.

Who should avoid it

Check these before anything else.
  • Low blood pressure, since it widens blood vessels
  • No formal contraindications established

Stop and get help

These are emergencies. Seek care.
  • Feeling faint or very dizzy, which can signal a blood-pressure drop
  • Signs of an allergic reaction such as face or throat swelling, hives, or trouble breathing

Common effects

Expected, and usually mild.
  • Diarrhea
  • A drop in blood pressure, which is the main known effect
  • In a large COVID trial it was stopped for lack of benefit, not for safety problems

Where this page says nothing is established, that means nobody has studied it, not that a compound is safe.

08

Is VIP (Vasoactive Intestinal Peptide) approved?

And where the numbers on this page come from.
Research only

No. Not FDA-approved.

Sold for research use only. Not cleared for human consumption or medical use.

  • DoseFrom research and community reports. No regulator has reviewed this dose.
  • Vial sizeFrom what vendors typically list; not a recommendation.
  • Reviewed22 July 2026
09

What else is like VIP (Vasoactive Intestinal Peptide)?

Others in Healing and recovery, side by side.

If you're weighing VIP (Vasoactive Intestinal Peptide), it's worth reading PDA (Pentadeca Arginate), GLOW blend, and KLOW blend in the same class.

10

What these words mean

Show glossary +
Titrate
Starting at a low dose and increasing it slowly over time so your body adjusts and side effects stay mild.
Subcutaneous
An injection just under the skin, into the fat layer, usually with a short, thin insulin needle.
Intramuscular (IM)
An injection into a muscle, using a longer needle.
Reconstitution
Mixing a powdered peptide with liquid (bacteriostatic water) so it can be drawn into a syringe.
Bacteriostatic water
Sterile water with a tiny amount of preservative, used to mix powdered peptides.
Concentration
How strong the mixed peptide is, in milligrams per milliliter (mg/mL). More water makes it weaker; less water makes it stronger.
Units (on the syringe)
The marks on an insulin syringe. 100 units equals 1 mL. They measure how much liquid you draw, not the dose in milligrams.
mcg and mg
Units of dose. 1 milligram (mg) equals 1,000 micrograms (mcg).
GLP-1
A natural gut hormone that lowers appetite and blood sugar. Drugs that copy it, like semaglutide, are used for weight loss.
Growth hormone secretagogue
A compound that nudges your body to release more of its own growth hormone, rather than injecting the hormone itself.
Half-life
How long a compound stays active in your body. A longer half-life means you inject less often.
Peptide vs small molecule
A peptide is a short chain of amino acids. A few items here (like MK-677 or methylene blue) are small molecules, not true peptides, but people use them the same way.
Research only
No approved dose or use in people. Sold for research and not reviewed by the FDA for safety or quality.
Investigational
Still being tested in clinical trials and not yet approved or legally sold for general use.
Banned in drug-tested sport
Prohibited by the World Anti-Doping Agency (WADA); using it can disqualify a competing athlete.

Last reviewed 22 July 2026