Coremend blend (TB-500 / BPC-157 / KPV)_Dosage, benefits & legal status
Also known as Coremend, TB-500 + BPC-157 + KPV, BPC-157 + TB-500 + KPV, KPV + BPC-157 + TB-500, Tri Blend, Tri-Heal, BPC/TB/KPV
A named healing triple that is the Wolverine blend with KPV added.
Common vial size is what vendors typically sell, not a recommendation. Enter your own vial in the calculator.
What is Coremend blend (TB-500 / BPC-157 / KPV)?
Plain language first. The technical label stays, but it never stands alone.Overview
The Wolverine blend with KPV added. The TB-500 share is two and a half times the others, so a dose worked out for a 1:1 vial gives you far more TB-500 than you expect.
A research-market three-peptide co-formulation supplied as TB-500 25 mg, BPC-157 10 mg and KPV 10 mg in a 45 mg vial, sold under the product name Coremend. Compositionally it is the BPC-157 plus TB-500 pairing with the alpha-MSH fragment KPV added, and it differs from the KLOW blend by the absence of GHK-Cu. No published trial has evaluated the combination.
What it's used for
An injected three-peptide blend sold for tissue repair, recovery and inflammation.
How does Coremend blend (TB-500 / BPC-157 / KPV) work?
What it does in the body, and where.Coremend sits between two blends this library already covers, and the interesting part is the ratio rather than the ingredients.
- 01It is Wolverine plus KPVBPC-157 and TB-500 are the two most-sold healing peptides. KPV is a three-amino-acid fragment of alpha-MSH marketed for inflammation. Add GHK-Cu and you have KLOW.
- 02The ratio is uneven, and that mattersTB-500 sits at 25 mg against 10 mg each for the others. Every other blend in this family is close to 1:1, so a dose worked out from a Wolverine vial does not carry over.
- 03The evidence does not improve by stackingBPC-157 has no completed published randomized efficacy trial. TB-500 is a short fragment rather than the full thymosin beta-4 protein whose trials are usually quoted for it. KPV's work is mostly in animal models of colitis. Three thin evidence bases in one vial remain three thin evidence bases.
Where this compound is thought to act.
What else is it used for?
Each use below carries its own evidence level. Approved means regulators have cleared it for that purpose. Investigational means it is in trials. Early research means it is being studied and is not established.
- Tissue and tendon repair, from the BPC-157 and TB-500 halvesResearch only
- Gut inflammation, which is KPV's own claimResearch only
- Recovery after injury, which is what the blend is marketed fornone
The published record
0
Papers and trials about Coremend blend (TB-500 / BPC-157 / KPV)
Europe PMC was searched on 12 October 2026 and returned nothing.
Counted from Europe PMC indexing, not read by a person.
At a glance
Four things to know about Coremend blend (TB-500 / BPC-157 / KPV)
Evidence
Category
Healing and recovery
Common vial
Varies
Half-life
None of the three has a published human figure
How much, and do you cycle it?
The range, and whether you take breaks.0.25 up to 0.5 mg BPC-157 per day (the rest follows your ratio), varies. Not established for the blend No range
No schedule has been studied for this combination. The components have different clearance times and different conventional frequencies, so a single shared schedule is a convenience of the vial rather than a finding.
None of the three has a published human figureNo figure
BPC-157 has a rodent figure only. KPV has nothing published. The half-life quoted for TB-500 usually belongs to full-length thymosin beta-4, which is a different molecule. A blend has no single half-life. Each component clears on its own schedule, so one draw starts two or more different clocks. See each component's page.
You can compare this against the whole library to see where it sits.
How do I dose and price it?
Enter your vial and your dose. Pick a mix. We show the draw and the cost.The vial holds a fixed amount of drug. Adding more water does not make more drug, it just spreads it thinner, so you draw a bigger number on the syringe for the same dose.
The published configuration is TB-500 25 mg, BPC-157 10 mg and KPV 10 mg in a 45 mg vial. Note the ratio is not 1:1: TB-500 is present at two and a half times the others, which is unusual in this family and changes what a single draw delivers. Coremend is one vendor's product name, so another seller's three-peptide healing vial may hold different amounts under a different name. Other sellers sell an even 10/10/10 vial of the same three peptides, often as Tri Blend.
Pick your vial to see concentrations and a draw.
Choose your mix
Measuring the water1 mL = one full 100-unit syringe.
Your draw
What one draw delivers
The same arithmetic as the calculator, worked out for the vials vendors sell.Dose anchored to BPC-157, at the 0.25 to 0.5 mg per day people commonly cite. Each table assumes one draw per day. If you split it across more injections, divide the reading by the number of injections.
| BPC-157 dose | 1 mL water | 2 mL water | 3 mL water |
|---|---|---|---|
| 0.25 mg | 2.5 units
| 5.0 units
| 7.5 units
|
| 0.5 mg | 5.0 units
| 10.0 units
| 15.0 units
|
| BPC-157 dose | 1 mL water | 2 mL water | 3 mL water |
|---|---|---|---|
| 0.25 mg | 2.5 units
| 5.0 units
| 7.5 units
|
| 0.5 mg | 5.0 units
| 10.0 units
| 15.0 units
|
No published human study establishes a dose for this blend. The range comes from vendor and community practice and is anchored to one component, because a blend is one draw.
On the 25/10/10 vial, a draw giving 500 mcg of BPC-157 gives 500 mcg of KPV and 1.25 mg of TB-500 alongside it. Daily dosing at that rate puts TB-500 near 8.75 mg per week, well above its own commonly cited 2 to 5 mg weekly range, and delivers it daily where it is usually given two or three times a week. The uneven ratio is the reason this blend behaves differently from the 1:1 Wolverine vial. On the even 10/10/10 vial the same draw gives 500 mcg each of TB-500 and KPV, which puts TB-500 near 3.5 mg per week, inside its commonly cited range.
Coremend blend (TB-500 / BPC-157 / KPV) starts at $83.30 across 7 vendors, typically $2.78 – $10.00 per mg.
9 listings, last read Oct 10, 2026. Shipping and card fees are not included.
How do you store it?
Before mixing, and after.Dry powder in the freezer or fridge. Once mixed, fridge, and use within about a month.
Unmixed lyophilized Coremend blend (TB-500 / BPC-157 / KPV) keeps for a long time cold. Once you add water the clock starts: most reconstituted vials hold up for roughly 28 to 30 days at fridge temperature. Keep it out of light, and do not freeze it after mixing.
What are the side effects and cautions?
Known cautions and warnings for this compound.Who should avoid it
- Pregnancy or breastfeeding
- Active cancer, as a precaution with anything that promotes tissue or blood-vessel growth
- Anyone competing in drug-tested sport, because TB-500 is named on the WADA prohibited list
- Anyone who wants established safety data, because none exists for this combination in humans
Stop and get help
- Signs of an allergic reaction, including spreading hives, facial or throat swelling, or trouble breathing
- Redness, heat, or pus at the injection site, which can signal infection
- Any new lump or unexplained symptom
Common effects
- Redness, soreness, or a small bump at the injection site
- Beyond that, unknown. No study has recorded what this combination commonly causes
Where this page says nothing is established, that means nobody has studied it, not that a compound is safe.
Is Coremend blend (TB-500 / BPC-157 / KPV) approved?
And where the numbers on this page come from.No. Coremend blend (TB-500 / BPC-157 / KPV) is not approved for any use, anywhere. It is sold labeled for laboratory research only, and there is no legal route to buy it for human use.
- Approval statusResearch only
- RouteUnder the skin (subcutaneous)
- Checked24 August 2026
- DoseFrom community reports. No regulator or trial established this dose.
- Vial sizeFrom what vendors typically list; not a recommendation.
- SourcesNone traced yet.
What has happened recently
We have not yet written a full regulatory note for this compound. The status above is current as of the date shown.
Banned in drug-tested sport. Most research peptides are prohibited under WADA's S0 category, which covers any substance with no approval from any regulatory authority for human use. That means a compound can be banned without ever being named on the prohibited list. Check with your own anti-doping authority rather than assuming absence from the list means permitted.
You can compare this against the whole library, or read how to check a seller.
What else is like Coremend blend (TB-500 / BPC-157 / KPV)?
Others in Healing and recovery, side by side.If you're weighing Coremend blend (TB-500 / BPC-157 / KPV), it's worth reading Vesilute, Cerebroprotein Hydrolysate, and Regeno blend (BPC-157 / TB-500 / Cartalax) in the same class.
A named healing triple that is the Wolverine blend with KPV added.
- Dose
- 0.25 up to 0.5 mg BPC-157 per day (the rest follows your ratio)
- How often
- Varies
A lab-made 2 amino acid peptide aimed at the bladder.
- Dose
- Research only
- How often
- Daily, in 10-20 day courses
A generic name for pig-brain peptide mixtures, sometimes including Cerebrolysin itself.
- Dose
- Given in the hospital as a course of daily infusions
- How often
- Hospital courses of daily infusions
The Wolverine blend with a cartilage bioregulator added.
- Dose
- 0.25 up to 0.5 mg BPC-157 per day (the rest follows your ratio)
- How often
- Varies
Guides for this compound
- How to Reconstitute a Peptide
Mix peptide powder with bacteriostatic water, step by step.
- How to Read an Insulin Syringe
Read the units, convert to millilitres, and draw the exact dose.
- mcg vs mg: The Peptide Dosing Mistake to Avoid
Your vial says mg and your protocol says mcg. Here is the conversion and how to check it.
- How to Read a Peptide COA
What the purity number does and does not tell you, and how to spot an edited report.
- How to Vet a Peptide Vendor
Independent COAs, HPLC purity, and the red flags that mean walk away.
Sources
No primary source has been traced for this compound yet. Treat everything on this page as unverified until one is. How we grade evidence