CJC-1295 with DAC_
Also known as CJC-1295 DAC, DAC:GRF
A once-or-twice-weekly shot that keeps your growth hormone raised for days.
Common vial size is what vendors typically sell, not a recommendation. Enter your own vial in the calculator.
What is CJC-1295 with DAC?
Plain language first. The technical label stays, but it never stands alone.Overview
CJC-1295 with DAC is a long-acting GHRH analog, a copy of the hormone that tells your body to make growth hormone, with a molecular anchor ('DAC') that keeps it working for days. In plain terms: it raises your own growth hormone steadily from a single weekly or twice-weekly shot.
What it's used for
A long-acting shot that keeps growth hormone raised for days, used to build muscle, burn fat, recover, and sleep better. You inject it only once or twice a week.
How does CJC-1295 with DAC work?
What it does in the body, and where.CJC-1295 copies GHRH, the hormone that tells your pituitary to make growth hormone. The DAC version carries a molecular anchor that keeps it circulating for days rather than minutes.
- 01It copies your growth hormone releasing hormonePrompting the pituitary from upstream, rather than supplying growth hormone directly.
- 02The DAC anchor binds it to a blood proteinThat is what stretches its working life from minutes to roughly a week, and it is the only difference from the no-DAC version.
- 03A raised baseline, not a pulseBecause it stays active for days, it lifts your overall level rather than producing the natural pulses. Whether that matters is genuinely debated.
What else is it used for?
Each group carries its own evidence level.Approved means regulators have cleared it for that purpose. Investigational means it is in trials. Early research means it is being studied and is not established.
Growth hormone release
Research only- Human trialIn a small early human study, one injection raised growth hormone 2 to 10-fold for more than six days.
- Human trialIGF-1, the hormone growth hormone works through, rose 1.5 to 3-fold for 9 to 11 days.
- Human trialAfter repeated doses, IGF-1 stayed above baseline for up to 28 days.
- No dataIt was never approved, development stopped, and it is banned in drug-tested sport.
The 2 to 10-fold growth hormone numbers come from this DAC version specifically. They are routinely misapplied to the no-DAC version, which behaves completely differently.
How much, and do you cycle it?
The range, and whether you take breaks.1 up to 2 mg per dose (start low, increase slowly), 1-2x per week. Commonly cycled, usually 8 to 12 weeks on and 4 offCommunity practice
Commonly cycled 8 to 12 weeks on and 4 off, and no study has tested that. The argument for it is that this version holds growth hormone at a raised baseline rather than restoring pulses. Worth knowing that when GHRH itself was infused continuously for 14 days in people, the pituitary did not run down. So the tolerance case for cycling this one is an inference from related drugs, not something anyone has measured in it.
How do I dose and price it?
Enter your vial and your dose. Pick a mix. We show the draw and the cost.The vial holds a fixed amount of drug. Adding more water does not make more drug, it just spreads it thinner, so you draw a bigger number on the syringe for the same dose.
Choose your mix
Measuring the water1 mL = one full 100-unit syringe.
Your draw
40 / 100 unitsHow do you store it?
Before mixing, and after.Dry powder in the freezer or fridge. Once mixed, fridge, and use within about a month.
Unmixed lyophilized CJC-1295 with DAC keeps for a long time cold. Once you add water the clock starts: most reconstituted vials hold up for roughly 28 to 30 days at fridge temperature. Keep it out of light, and do not freeze it after mixing.
What are the side effects and cautions?
Known cautions and warnings for this compound.Can cause a histamine flush: temporary flushing, itching, or welts near the injection, usually mild and short-lived. Injecting slowly helps. If it spreads, or you get facial or throat swelling or trouble breathing, treat it as a reaction and get help immediately.
Community notes: what actually helps
What actually helps, according to the people doing it
Nobody's running trials on this. What follows is the folk wisdom that keeps surfacing in Reddit, peptide forums, and the Discord groups, sorted from "probably real" to "someone swears by it." Keep in mind, NONE of this is doctor advice.
The tip that comes up most on r/peptides is to add more water. Mix your vial with 3 or 4mL of bac water instead of 1 to 2mL. Same dose, spread thinner, so your skin reacts less.
- Let it warm to room temperature. Cold stings more.
- Let the alcohol dry fully before the needle goes in.
- Inject slow, over five to ten seconds.
- Move your spot around, at least an inch from last time.
- For a hard lump, warm compress after. For a red itchy welt, ice.
This is where Benadryl and Zyrtec come up constantly on the boards. Most people take one 30 to 60 minutes before the shot if they know they tend to react. Claritin works too. Some skip the pill and use Benadryl cream before, or hydrocortisone cream after. Quercetin gets mentioned a lot as the gentler, natural option.
One heads up you'll also see repeated: taking an allergy pill before every shot can hide a real allergy building underneath. That's why some people don't do it by default.
In the more advanced threads, people keep KPV around and inject it when a reaction flares, and say it clears fast. Others try low-dose naltrexone (LDN) as a longer-term fix, but that's real experimenter territory. And a common reminder on the forums: if your reactions are suddenly bad or started with a new vial, the peptide itself might be the problem, not you.
Redness that spreads past a couple inches, streaks, feels hot, oozes, or comes with a fever means a possible infection. See a doctor. Hives all over, a swollen face or throat, or trouble breathing is a real allergic reaction. Act on that right away.
Who should avoid it
- Active cancer
- Pregnancy
- Banned in drug-tested sport
Stop and get help
- Spreading hives, face or throat swelling, or trouble breathing
- New lumps or masses
Common effects
- Flushing, itching, or a welt near the injection, which is a histamine effect rather than an allergy
- Water retention
- Tingling in the hands
- Tiredness
- Because it lasts for days, any effect lingers
Where this page says nothing is established, that means nobody has studied it, not that a compound is safe.
Is CJC-1295 with DAC approved?
And where the numbers on this page come from.No. Not FDA-approved.
Sold for research use only. Not cleared for human consumption or medical use.
- DoseFrom research and community reports. No regulator has reviewed this dose.
- Vial sizeFrom what vendors typically list; not a recommendation.
- Sources
- Reviewed22 July 2026
What else is like CJC-1295 with DAC?
Others in Growth hormone, side by side.If you're weighing CJC-1295 with DAC, it's worth reading Ipamorelin, CJC-1295 no DAC (Mod GRF 1-29), and Sermorelin in the same class.
A once-or-twice-weekly shot that keeps your growth hormone raised for days.
- Dose
- 1 up to 2 mg per dose (start low, increase slowly)
- How often
- 1-2x per week
A gentle shot that nudges your body to release its own growth hormone.
- Dose
- 0.2 up to 0.3 mg per dose (start low, increase slowly)
- How often
- Daily, often at night
A short-acting growth-hormone pulse, usually paired with ipamorelin.
- Dose
- 0.1 mg per dose
- How often
- Daily to 2x daily
A gentle shot that prompts your body to make more of its own growth hormone.
- Dose
- 0.2 up to 0.5 mg per dose (start low, increase slowly)
- How often
- Daily/nightly
10What these words mean
Show glossary +
What these words mean
- Titrate
- Starting at a low dose and increasing it slowly over time so your body adjusts and side effects stay mild.
- Subcutaneous
- An injection just under the skin, into the fat layer, usually with a short, thin insulin needle.
- Intramuscular (IM)
- An injection into a muscle, using a longer needle.
- Reconstitution
- Mixing a powdered peptide with liquid (bacteriostatic water) so it can be drawn into a syringe.
- Bacteriostatic water
- Sterile water with a tiny amount of preservative, used to mix powdered peptides.
- Concentration
- How strong the mixed peptide is, in milligrams per milliliter (mg/mL). More water makes it weaker; less water makes it stronger.
- Units (on the syringe)
- The marks on an insulin syringe. 100 units equals 1 mL. They measure how much liquid you draw, not the dose in milligrams.
- mcg and mg
- Units of dose. 1 milligram (mg) equals 1,000 micrograms (mcg).
- GLP-1
- A natural gut hormone that lowers appetite and blood sugar. Drugs that copy it, like semaglutide, are used for weight loss.
- Growth hormone secretagogue
- A compound that nudges your body to release more of its own growth hormone, rather than injecting the hormone itself.
- Half-life
- How long a compound stays active in your body. A longer half-life means you inject less often.
- Peptide vs small molecule
- A peptide is a short chain of amino acids. A few items here (like MK-677 or methylene blue) are small molecules, not true peptides, but people use them the same way.
- Research only
- No approved dose or use in people. Sold for research and not reviewed by the FDA for safety or quality.
- Investigational
- Still being tested in clinical trials and not yet approved or legally sold for general use.
- Banned in drug-tested sport
- Prohibited by the World Anti-Doping Agency (WADA); using it can disqualify a competing athlete.
Sources
Last reviewed 22 July 2026