CJC-1295 no DAC (Mod GRF 1-29)_Dosage, benefits & legal status
Also known as Mod GRF 1-29, Modified GRF 1-29, CJC-1295 without DAC, CJC-1295 no DAC
A short-acting growth-hormone pulse, usually paired with ipamorelin.
Common vial size is what vendors typically sell, not a recommendation. Enter your own vial in the calculator.
What is CJC-1295 no DAC (Mod GRF 1-29)?
Plain language first. The technical label stays, but it never stands alone.Overview
It gives a quick pulse of growth hormone, closer to your body's natural rhythm. Then it clears fast, so it is usually paired with ipamorelin.
CJC-1295 without DAC (also called Mod GRF 1-29) is the short-acting version of the same GHRH analog.
What it's used for
The short-acting version that gives a quick growth-hormone pulse closer to your body's natural rhythm. It is usually paired with ipamorelin for muscle, fat loss, and recovery.
How does CJC-1295 no DAC (Mod GRF 1-29) work?
What it does in the body, and where.This is the same GHRH copy as CJC-1295 with DAC, minus the anchor that makes it last. That one difference changes everything about how it behaves.
- 01It prompts the pituitary through the GHRH receptorIdentical mechanism to the DAC version.
- 02It clears in about half an hourProducing a pulse rather than a raised baseline, which is closer to how your body releases growth hormone naturally.
- 03The famous figures do not apply hereThe two-to-tenfold growth hormone numbers quoted for CJC-1295 come from the DAC version only. This is the most common mix-up on this compound.
What else is it used for?
Each group carries its own evidence level.Approved means regulators have cleared it for that purpose. Investigational means it is in trials. Early research means it is being studied and is not established.
Growth hormone release
Research only- No dataThere is no published human trial of this version specifically.
- Human trialIts half-life is about 30 minutes, against roughly a week for the DAC version, so it behaves completely differently.
The famous 2 to 10-fold growth hormone figures are from the DAC version and do not apply here. This version has no published human trial of its own and clears in about 30 minutes rather than a week.
The published record
3
Records indexed for CJC-1295 no DAC (Mod GRF 1-29)
1 in humans, 0 of them original studies.
FDA: Nominated but withdrawn; previously category 2.
Counted from Europe PMC indexing, not read by a person. Human means indexed under humans, which includes reviews and work on human cells. Original studies exclude reviews and lab work on human cells.Last updated 12 September 2026.
At a glance
Four things to know about CJC-1295 no DAC (Mod GRF 1-29)
Evidence
Research only
Category
Growth hormone
Common vial
5 mg
Half-life
Not measured in humans
How much, and do you cycle it?
The range, and whether you take breaks.0.1 mg per dose, daily to 2x daily. Commonly cycled, usually 8 to 12 weeks on and 4 offCommunity practice
Because it clears in about half an hour it produces a pulse rather than a raised baseline, which is the argument users give for needing less of a break than the DAC version. Neither schedule has been tested.
Source: Somatotroph desensitisation during continuous GHRH infusion in normal men (J Clin Endocrinol Metab)
How long does it stay in the body?
The half-life, and where the figure comes from.Not measured in humansNo figure
The 30 minute figure is repeated everywhere and traces to no published human measurement.
You can compare this against the whole library to see where it sits.
How do I dose and price it?
Enter your vial and your dose. Pick a mix. We show the draw and the cost.The vial holds a fixed amount of drug. Adding more water does not make more drug, it just spreads it thinner, so you draw a bigger number on the syringe for the same dose.
Choose your mix
Measuring the water1 mL = one full 100-unit syringe.
Your draw
4 / 100 unitsCJC-1295 no DAC (Mod GRF 1-29) starts at $24.99 across 52 vendors, typically $5.00 – $19.35 per mg.
126 listings, last read Sep 6, 2026. Shipping and card fees are not included.
How do you store it?
Before mixing, and after.Dry powder in the freezer or fridge. Once mixed, fridge, and use within about a month.
Unmixed lyophilized CJC-1295 no DAC (Mod GRF 1-29) keeps for a long time cold. Once you add water the clock starts: most reconstituted vials hold up for roughly 28 to 30 days at fridge temperature. Keep it out of light, and do not freeze it after mixing.
What are the side effects and cautions?
Known cautions and warnings for this compound.Can cause a histamine flush: temporary flushing, itching, or welts near the injection, usually mild and short-lived. Injecting slowly helps. If it spreads, or you get facial or throat swelling or trouble breathing, treat it as a reaction and get help immediately.
Who should avoid it
- Active cancer, as a precaution with anything raising growth hormone
- Pregnancy
- Banned in drug-tested sport
Stop and get help
- Spreading hives, face or throat swelling, or trouble breathing
- New lumps or masses
Common effects
- Flushing or a welt near the injection
- Injection-site reactions
- Headache
- No controlled trials of this specific compound exist, so these are reported rather than measured
What regulators say
- FDA: Certain Bulk Drug Substances for Use in Compounding that May Present Significant Safety Risks (category 2 and withdrawn nominations), current as of April 22, 2026Nominated but withdrawn; previously category 2
FDA lists CJC-1295 without distinguishing the DAC and no-DAC forms
Checked 11 September 2026
What actually helps, according to the people doing it
Nobody's running trials on this. What follows is the folk wisdom that keeps surfacing in Reddit, peptide forums, and the Discord groups, sorted from "probably real" to "someone swears by it." Keep in mind, NONE of this is doctor advice.
Change how you inject (this helps most people)
The tip that comes up most on r/peptides is to add more water. Mix your vial with 3 or 4mL of bac water instead of 1 to 2mL. Same dose, spread thinner, so your skin reacts less.
Small habits people swear by
- 1Let it warm to room temperature. Cold stings more.
- 2Let the alcohol dry fully before the needle goes in.
- 3Inject slow, over five to ten seconds.
- 4Move your spot around, at least an inch from last time.
- 5For a hard lump, warm compress after. For a red itchy welt, ice.
Treat the itch
This is where Benadryl and Zyrtec come up constantly on the boards. Most people take one 30 to 60 minutes before the shot if they know they tend to react. Claritin works too. Some skip the pill and use Benadryl cream before, or hydrocortisone cream after. Quercetin gets mentioned a lot as the gentler, natural option.
One heads up you'll also see repeated: taking an allergy pill before every shot can hide a real allergy building underneath. That's why some people don't do it by default.
The deeper end
In the more advanced threads, people keep KPV around and inject it when a reaction flares, and say it clears fast. Others try low-dose naltrexone (LDN) as a longer-term fix, but that's real experimenter territory. And a common reminder on the forums: if your reactions are suddenly bad or started with a new vial, the peptide itself might be the problem, not you.
Redness that spreads past a couple inches, streaks, feels hot, oozes, or comes with a fever means a possible infection. See a doctor. Hives all over, a swollen face or throat, or trouble breathing is a real allergic reaction. Act on that right away.
Where this page says nothing is established, that means nobody has studied it, not that a compound is safe.
Is CJC-1295 no DAC (Mod GRF 1-29) approved?
And where the numbers on this page come from.No. CJC-1295 no DAC (Mod GRF 1-29) is not approved for any use, anywhere. It is sold labelled for laboratory research only, and there is no legal route to buy it for human use.
- Approval statusResearch only
- RouteUnder the skin (subcutaneous)
- CheckedAugust 2026
What has happened recently
We have not yet written a full regulatory note for this compound. The status above is current as of the date shown.
Banned in drug-tested sport. Most research peptides are prohibited under WADA's S0 category, which covers any substance with no approval from any regulatory authority for human use. That means a compound can be banned without ever being named on the prohibited list. Check with your own anti-doping authority rather than assuming absence from the list means permitted.
You can compare this against the whole library, or read how to check a seller.
- DoseFrom research and community reports. No regulator has reviewed this dose.
- Vial sizeFrom what vendors typically list; not a recommendation.
- Sources
- Reviewed14 August 2026
What else is like CJC-1295 no DAC (Mod GRF 1-29)?
Others in Growth hormone peptides, side by side.If you're weighing CJC-1295 no DAC (Mod GRF 1-29), it's worth reading Sermorelin, Tesamorelin, and GHRP-2 in the same class.
A short-acting growth-hormone pulse, usually paired with ipamorelin.
- Dose
- 0.1 mg per dose
- How often
- Daily to 2x daily
A gentle shot that prompts your body to make more of its own growth hormone.
- Dose
- 0.2 up to 0.5 mg per dose (start low, increase slowly)
- How often
- Daily/nightly
An approved shot proven to shrink stubborn belly fat.
- Dose
- 1.28 up to 2 mg per day, depending on which product you have
- How often
- Daily
A shot that spikes your own growth hormone to build muscle and recover.
- Dose
- 0.1 up to 0.3 mg per dose (start low, increase slowly)
- How often
- 1-3x daily
Guides for this compound
- How to Reconstitute a Peptide
Mix peptide powder with bacteriostatic water, step by step.
- How to Read an Insulin Syringe
Read the units, convert to millilitres, and draw the exact dose.
- mcg vs mg: The Peptide Dosing Mistake to Avoid
Your vial says mg and your protocol says mcg. Here is the conversion and how to check it.
- Why Does My Peptide Injection Itch or Welt
Injection-site irritation, a histamine reaction, or a true allergy, and how to tell them apart.
- How to Read a Peptide COA
What the purity number does and does not tell you, and how to spot an edited report.
Sources
- Teichman CJC-1295 trial (DAC version), Journal of Clinical Endocrinology and Metabolism, 2006(2006)This paper is cited constantly in support of CJC-1295 without DAC, and it did not test that molecule. What Teichman and colleagues gave to healthy adults was the drug affinity complex version, carrying a maleimidopropionic acid group that binds covalently to cysteine 34 on serum albumin, and that conjugation is the entire reason the half-life came out at 5.8 to 8.1 days and IGF-I stayed elevated for nine to eleven days after one injection. Strip the DAC off and you have modified GRF (1-29), a molecule cleared in minutes rather than days. The trial is listed here rather than removed because a reader is likely to meet it quoted elsewhere as evidence for this compound, and the useful thing is to know why it is not. The honest position for CJC-1295 without DAC is that no equivalent human pharmacokinetic trial has been traced for it.
Last reviewed 14 August 2026
Beyond these, 3 records are indexed. Browse the records