CJC-1295 no DAC (Mod GRF 1-29)_
Also known as Mod GRF 1-29, Modified GRF 1-29, CJC-1295 without DAC
A short-acting growth-hormone pulse, usually paired with ipamorelin.
Common vial size is what vendors typically sell, not a recommendation. Enter your own vial in the calculator.
What is CJC-1295 no DAC (Mod GRF 1-29)?
Plain language first. The technical label stays, but it never stands alone.Overview
CJC-1295 without DAC (also called Mod GRF 1-29) is the short-acting version of the same GHRH analog. In plain terms: it gives a quick pulse of growth hormone closer to your body's natural rhythm, then clears fast, so it is usually paired with ipamorelin.
What it's used for
The short-acting version that gives a quick growth-hormone pulse closer to your body's natural rhythm. It is usually paired with ipamorelin for muscle, fat loss, and recovery.
How does CJC-1295 no DAC (Mod GRF 1-29) work?
What it does in the body, and where.This is the same GHRH copy as CJC-1295 with DAC, minus the anchor that makes it last. That one difference changes everything about how it behaves.
- 01It prompts the pituitary through the GHRH receptorIdentical mechanism to the DAC version.
- 02It clears in about half an hourProducing a pulse rather than a raised baseline, which is closer to how your body releases growth hormone naturally.
- 03The famous figures do not apply hereThe two-to-tenfold growth hormone numbers quoted for CJC-1295 come from the DAC version only. This is the most common mix-up on this compound.
What else is it used for?
Each group carries its own evidence level.Approved means regulators have cleared it for that purpose. Investigational means it is in trials. Early research means it is being studied and is not established.
Growth hormone release
Research only- No dataThere is no published human trial of this version specifically.
- Human trialIts half-life is about 30 minutes, against roughly a week for the DAC version, so it behaves completely differently.
The famous 2 to 10-fold growth hormone figures are from the DAC version and do not apply here. This version has no published human trial of its own and clears in about 30 minutes rather than a week.
How much, and do you cycle it?
The range, and whether you take breaks.0.1 mg per dose, daily to 2x daily. Commonly cycled, usually 8 to 12 weeks on and 4 offCommunity practice
Because it clears in about half an hour it produces a pulse rather than a raised baseline, which is the argument users give for needing less of a break than the DAC version. Neither schedule has been tested.
Source: Somatotroph desensitisation during continuous GHRH infusion in normal men (J Clin Endocrinol Metab)
How do I dose and price it?
Enter your vial and your dose. Pick a mix. We show the draw and the cost.The vial holds a fixed amount of drug. Adding more water does not make more drug, it just spreads it thinner, so you draw a bigger number on the syringe for the same dose.
Choose your mix
Measuring the water1 mL = one full 100-unit syringe.
Your draw
4 / 100 unitsHow do you store it?
Before mixing, and after.Dry powder in the freezer or fridge. Once mixed, fridge, and use within about a month.
Unmixed lyophilized CJC-1295 no DAC (Mod GRF 1-29) keeps for a long time cold. Once you add water the clock starts: most reconstituted vials hold up for roughly 28 to 30 days at fridge temperature. Keep it out of light, and do not freeze it after mixing.
What are the side effects and cautions?
Known cautions and warnings for this compound.Can cause a histamine flush: temporary flushing, itching, or welts near the injection, usually mild and short-lived. Injecting slowly helps. If it spreads, or you get facial or throat swelling or trouble breathing, treat it as a reaction and get help immediately.
Community notes: what actually helps
What actually helps, according to the people doing it
Nobody's running trials on this. What follows is the folk wisdom that keeps surfacing in Reddit, peptide forums, and the Discord groups, sorted from "probably real" to "someone swears by it." Keep in mind, NONE of this is doctor advice.
The tip that comes up most on r/peptides is to add more water. Mix your vial with 3 or 4mL of bac water instead of 1 to 2mL. Same dose, spread thinner, so your skin reacts less.
- Let it warm to room temperature. Cold stings more.
- Let the alcohol dry fully before the needle goes in.
- Inject slow, over five to ten seconds.
- Move your spot around, at least an inch from last time.
- For a hard lump, warm compress after. For a red itchy welt, ice.
This is where Benadryl and Zyrtec come up constantly on the boards. Most people take one 30 to 60 minutes before the shot if they know they tend to react. Claritin works too. Some skip the pill and use Benadryl cream before, or hydrocortisone cream after. Quercetin gets mentioned a lot as the gentler, natural option.
One heads up you'll also see repeated: taking an allergy pill before every shot can hide a real allergy building underneath. That's why some people don't do it by default.
In the more advanced threads, people keep KPV around and inject it when a reaction flares, and say it clears fast. Others try low-dose naltrexone (LDN) as a longer-term fix, but that's real experimenter territory. And a common reminder on the forums: if your reactions are suddenly bad or started with a new vial, the peptide itself might be the problem, not you.
Redness that spreads past a couple inches, streaks, feels hot, oozes, or comes with a fever means a possible infection. See a doctor. Hives all over, a swollen face or throat, or trouble breathing is a real allergic reaction. Act on that right away.
Who should avoid it
- Active cancer, as a precaution with anything raising growth hormone
- Pregnancy
- Banned in drug-tested sport
Stop and get help
- Spreading hives, face or throat swelling, or trouble breathing
- New lumps or masses
Common effects
- Flushing or a welt near the injection
- Injection-site reactions
- Headache
- No controlled trials of this specific compound exist, so these are reported rather than measured
Where this page says nothing is established, that means nobody has studied it, not that a compound is safe.
Is CJC-1295 no DAC (Mod GRF 1-29) approved?
And where the numbers on this page come from.No. Not FDA-approved.
Sold for research use only. Not cleared for human consumption or medical use.
- DoseFrom research and community reports. No regulator has reviewed this dose.
- Vial sizeFrom what vendors typically list; not a recommendation.
- Sources
- Reviewed22 July 2026
What else is like CJC-1295 no DAC (Mod GRF 1-29)?
Others in Growth hormone, side by side.If you're weighing CJC-1295 no DAC (Mod GRF 1-29), it's worth reading Ipamorelin, CJC-1295 with DAC, and Sermorelin in the same class.
A short-acting growth-hormone pulse, usually paired with ipamorelin.
- Dose
- 0.1 mg per dose
- How often
- Daily to 2x daily
A gentle shot that nudges your body to release its own growth hormone.
- Dose
- 0.2 up to 0.3 mg per dose (start low, increase slowly)
- How often
- Daily, often at night
A once-or-twice-weekly shot that keeps your growth hormone raised for days.
- Dose
- 1 up to 2 mg per dose (start low, increase slowly)
- How often
- 1-2x per week
A gentle shot that prompts your body to make more of its own growth hormone.
- Dose
- 0.2 up to 0.5 mg per dose (start low, increase slowly)
- How often
- Daily/nightly
10What these words mean
Show glossary +
What these words mean
- Titrate
- Starting at a low dose and increasing it slowly over time so your body adjusts and side effects stay mild.
- Subcutaneous
- An injection just under the skin, into the fat layer, usually with a short, thin insulin needle.
- Intramuscular (IM)
- An injection into a muscle, using a longer needle.
- Reconstitution
- Mixing a powdered peptide with liquid (bacteriostatic water) so it can be drawn into a syringe.
- Bacteriostatic water
- Sterile water with a tiny amount of preservative, used to mix powdered peptides.
- Concentration
- How strong the mixed peptide is, in milligrams per milliliter (mg/mL). More water makes it weaker; less water makes it stronger.
- Units (on the syringe)
- The marks on an insulin syringe. 100 units equals 1 mL. They measure how much liquid you draw, not the dose in milligrams.
- mcg and mg
- Units of dose. 1 milligram (mg) equals 1,000 micrograms (mcg).
- GLP-1
- A natural gut hormone that lowers appetite and blood sugar. Drugs that copy it, like semaglutide, are used for weight loss.
- Growth hormone secretagogue
- A compound that nudges your body to release more of its own growth hormone, rather than injecting the hormone itself.
- Half-life
- How long a compound stays active in your body. A longer half-life means you inject less often.
- Peptide vs small molecule
- A peptide is a short chain of amino acids. A few items here (like MK-677 or methylene blue) are small molecules, not true peptides, but people use them the same way.
- Research only
- No approved dose or use in people. Sold for research and not reviewed by the FDA for safety or quality.
- Investigational
- Still being tested in clinical trials and not yet approved or legally sold for general use.
- Banned in drug-tested sport
- Prohibited by the World Anti-Doping Agency (WADA); using it can disqualify a competing athlete.
Sources
Last reviewed 22 July 2026