Ipamorelin + CJC-1295 (no DAC) blend_Dosage, benefits & legal status
Also known as CJC/Ipa, Ipa/CJC, CJC-1295 + Ipamorelin, Ipamorelin + CJC-1295, Mod GRF 1-29 + Ipamorelin, CJC-1295 no DAC + Ipamorelin, Ipamorelin + CJC-1295 blend
The popular growth-hormone combo in one shot, for muscle, recovery, and sleep.
Common vial size is what vendors typically sell, not a recommendation. Enter your own vial in the calculator.
What is Ipamorelin + CJC-1295 (no DAC) blend?
Plain language first. The technical label stays, but it never stands alone.Overview
Together they nudge your body to release more of its own growth hormone than either alone, in one shot.
This is a blend of two growth-hormone signals: a GHRH analog that sets a steady base and a GHRP that adds a pulse. The CJC-1295 in these vials is almost always the no-DAC version, also called Mod GRF 1-29, because a short pulse is the whole point and the DAC version lasts about a week.
What it's used for
The most popular growth-hormone combo in one shot: one part sets a steady base and the other adds a clean pulse, for muscle, fat loss, recovery, and sleep.
How does Ipamorelin + CJC-1295 (no DAC) blend work?
What it does in the body, and where.The blend pairs two different signals that reach growth hormone release by separate routes, which is why they are combined rather than doubled up.
- 01CJC-1295 sets the base through the GHRH receptorRaising how much growth hormone is available to release.
- 02Ipamorelin adds a pulse through the ghrelin receptorTriggering the actual release. A different receptor, so the two do not compete.
- 03Together they produce more than either aloneThis is the reasoning behind the blend, and it is mechanistically sound even though the human evidence for the combination specifically is thin.
- 04The ratio varies by productThere is no standard mix, which is why this page shows no dose flag. Check each component's own page.
A schematic of the compound's mechanism, not a diagnostic image.
What else is it used for?
Each use below carries its own evidence level. Approved means regulators have cleared it for that purpose. Investigational means it is in trials. Early research means it is being studied and is not established.
- Building muscle, losing fat, and recovering fasterResearch only
- Deeper sleepResearch only
The published record
13
Records indexed for Ipamorelin + CJC-1295 (no DAC) blend
6 in humans, 0 of them original studies.
Counted from Europe PMC indexing, not read by a person. Human means indexed under humans, which includes reviews and work on human cells. Original studies exclude reviews and lab work on human cells.Last updated 11 September 2026.
At a glance
Four things to know about Ipamorelin + CJC-1295 (no DAC) blend
Evidence
Research only
Category
Muscle building
Common vial
10 mg
Half-life
About 2 hours, and one part never measured
How much, and do you cycle it?
The range, and whether you take breaks.~0.1 mg CJC-1295 per dose (the ipamorelin follows your ratio), daily, often at night. Each half is cycled on its own schedule, usually 8 to 12 weeks on and 4 offCommunity practice
The pairing exists because the two halves do not blunt each other. Losing response to a ghrelin-receptor peptide does not reduce the pituitary's response to a GHRH peptide, and the reverse is also true. No study has tested this blend on any schedule.
Source: 24-hour GHRP infusion attenuates the response to a later GHRP bolus (J Clin Endocrinol Metab, 1993)
How long does it stay in the body?
The half-life, and where the figure comes from.About 2 hours, and one part never measuredCommunity practice
Two compounds with nothing in common kinetically. Ipamorelin is put at about 2 hours, a figure that traces to no primary source. CJC-1295 without DAC has never been measured in a person at all. The blend cannot have a single number when half of it has no number.
Not yet traced to a primary source.
You can compare this against the whole library to see where it sits.
How do I dose and price it?
Enter your vial and your dose. Pick a mix. We show the draw and the cost.The vial holds a fixed amount of drug. Adding more water does not make more drug, it just spreads it thinner, so you draw a bigger number on the syringe for the same dose.
The 6 mg and 6 mg vial is the one named in the FDA's compounding briefing document, which makes it the only ratio here traceable to a primary source.
Pick your vial to see concentrations and a draw.
Choose your mix
Measuring the water1 mL = one full 100-unit syringe.
Your draw
Ipamorelin + CJC-1295 (no DAC) blend starts at $47.00 across 18 vendors, typically $7.50 – $16.99 per mg.
21 listings, last read Sep 5, 2026. Shipping and card fees are not included.
How do you store it?
Before mixing, and after.Dry powder in the freezer or fridge. Once mixed, fridge, and use within about a month.
Unmixed lyophilized Ipamorelin + CJC-1295 (no DAC) blend keeps for a long time cold. Once you add water the clock starts: most reconstituted vials hold up for roughly 28 to 30 days at fridge temperature. Keep it out of light, and do not freeze it after mixing.
What are the side effects and cautions?
Known cautions and warnings for this compound.Check which CJC-1295 is in your vial. The no-DAC version is standard in this blend, and the DAC version behaves so differently that it changes the whole schedule. Can cause a histamine flush: temporary flushing, itching, or welts near the injection, usually mild and short-lived. Injecting slowly helps. If it spreads, or you get facial or throat swelling or trouble breathing, treat it as a reaction and get help immediately.
Who should avoid it
- Active cancer, as a precaution with anything raising growth hormone
- Pregnancy
- Banned in drug-tested sport
Stop and get help
- Signs of an allergic reaction
- New lumps or masses
- Spreading hives, face or throat swelling, or trouble breathing
Common effects
- Headache
- Injection-site reactions
- Temporary fluid retention
- Reported in early-stage studies only. There is no large controlled safety database for general use
- Flushing or a welt near the injection
- No controlled trials of this specific compound exist, so these are reported rather than measured
- This is a blend of two growth-hormone peptides, so the cautions of both apply.
What actually helps, according to the people doing it
Nobody's running trials on this. What follows is the folk wisdom that keeps surfacing in Reddit, peptide forums, and the Discord groups, sorted from "probably real" to "someone swears by it." Keep in mind, NONE of this is doctor advice.
Change how you inject (this helps most people)
The tip that comes up most on r/peptides is to add more water. Mix your vial with 3 or 4mL of bac water instead of 1 to 2mL. Same dose, spread thinner, so your skin reacts less.
Small habits people swear by
- 1Let it warm to room temperature. Cold stings more.
- 2Let the alcohol dry fully before the needle goes in.
- 3Inject slow, over five to ten seconds.
- 4Move your spot around, at least an inch from last time.
- 5For a hard lump, warm compress after. For a red itchy welt, ice.
Treat the itch
This is where Benadryl and Zyrtec come up constantly on the boards. Most people take one 30 to 60 minutes before the shot if they know they tend to react. Claritin works too. Some skip the pill and use Benadryl cream before, or hydrocortisone cream after. Quercetin gets mentioned a lot as the gentler, natural option.
One heads up you'll also see repeated: taking an allergy pill before every shot can hide a real allergy building underneath. That's why some people don't do it by default.
The deeper end
In the more advanced threads, people keep KPV around and inject it when a reaction flares, and say it clears fast. Others try low-dose naltrexone (LDN) as a longer-term fix, but that's real experimenter territory. And a common reminder on the forums: if your reactions are suddenly bad or started with a new vial, the peptide itself might be the problem, not you.
Redness that spreads past a couple inches, streaks, feels hot, oozes, or comes with a fever means a possible infection. See a doctor. Hives all over, a swollen face or throat, or trouble breathing is a real allergic reaction. Act on that right away.
Where this page says nothing is established, that means nobody has studied it, not that a compound is safe.
Is Ipamorelin + CJC-1295 (no DAC) blend approved?
And where the numbers on this page come from.No. Ipamorelin + CJC-1295 (no DAC) blend is not approved for any use, anywhere. It is sold labelled for laboratory research only, and there is no legal route to buy it for human use.
- Approval statusResearch only
- RouteUnder the skin (subcutaneous)
- CheckedAugust 2026
What has happened recently
We have not yet written a full regulatory note for this compound. The status above is current as of the date shown.
Banned in drug-tested sport. Most research peptides are prohibited under WADA's S0 category, which covers any substance with no approval from any regulatory authority for human use. That means a compound can be banned without ever being named on the prohibited list. Check with your own anti-doping authority rather than assuming absence from the list means permitted.
You can compare this against the whole library, or read how to check a seller.
- DoseFrom research and community reports. No regulator has reviewed this dose.
- Vial sizeFrom what vendors typically list; not a recommendation.
- Sources
- Reviewed14 August 2026
What else is like Ipamorelin + CJC-1295 (no DAC) blend?
Others in Muscle building, side by side.If you're weighing Ipamorelin + CJC-1295 (no DAC) blend, it's worth reading IGF-1 LR3, IGF-1 DES, and Follistatin (FST-344) in the same class.
The popular growth-hormone combo in one shot, for muscle, recovery, and sleep.
- Dose
- ~0.1 mg CJC-1295 per dose (the ipamorelin follows your ratio)
- How often
- Daily, often at night
A powerful muscle-builder that also drops blood sugar hard.
- Dose
- 0.02 up to 0.05 mg per day (start low, increase slowly)
- How often
- Daily, cycled
A short-acting muscle-builder that works right where you inject it.
- Dose
- 0.05 up to 0.15 mg per dose (start low, increase slowly)
- How often
- Around training
An experimental muscle-builder that releases the body's brake on growth.
- Dose
- Research only
- How often
- Cycled
Guides for this compound
- How to Reconstitute a Peptide
Mix peptide powder with bacteriostatic water, step by step.
- How to Read an Insulin Syringe
Read the units, convert to millilitres, and draw the exact dose.
- mcg vs mg: The Peptide Dosing Mistake to Avoid
Your vial says mg and your protocol says mcg. Here is the conversion and how to check it.
- Why Does My Peptide Injection Itch or Welt
Injection-site irritation, a histamine reaction, or a true allergy, and how to tell them apart.
- How to Read a Peptide COA
What the purity number does and does not tell you, and how to spot an edited report.
Sources
- FDA, bulk drug substances for compounding that may present significant safety risks(2026)Both halves of this blend appear on FDA's safety-risk page, each for a different reason. For ipamorelin acetate, FDA cites a published study that identified serious adverse events including death when ipamorelin was given intravenously to improve gastric motility, notes that it contains unnatural amino acids that complicate characterisation, and says the agency has not identified safety information for certain other injectable routes. For CJC-1295, FDA cites serious adverse events including increased heart rate and a systemic vasodilatory reaction, and describes the available clinical data as limited. Nothing here evaluates the two given together, which is how the blend is sold and which has not been studied.
- FDA, bulk drug substances used in compounding under section 503A(2026)Defines what the categories mean. Category 2 is a compounding eligibility judgement about safety risk pending evaluation, not a finding that a substance does or does not work. It also records that FDA does not intend to place substances nominated on or after 7 January 2025 into these categories at all, so the absence of a newer compound from the list means nothing either way.
Last reviewed 14 August 2026
Beyond these, 13 records are indexed. Browse the records