Selank_Dosage, benefits & legal status
Also known as TP-7
A peptide that eases anxiety while keeping you clear-headed.
Common vial size is what vendors typically sell, not a recommendation. Enter your own vial in the calculator.
What is Selank?
Plain language first. The technical label stays, but it never stands alone.Overview
It gently tunes two of the brain's calming systems, GABA and serotonin. The aim is less anxiety without drowsiness or dependence.
Selank is a synthetic version of tuftsin, a natural immune-and-brain peptide, given as a nasal spray.
What it's used for
Eases anxiety and stress while keeping you clear-headed, without the sedation or dependence of anti-anxiety pills. It is often paired with Semax.
How does Selank work?
What it does in the body, and where.Selank is a synthetic version of tuftsin, a natural peptide that sits at the junction of immune and brain signalling.
- 01It slows the breakdown of calming moleculesRather than binding a receptor directly, it appears to extend how long your own calming signals last.
- 02Anxiety falls without sedationThis is the claim that distinguishes it from benzodiazepines, and the reason for the interest.
- 03Nasal, because it would not survive injection wellSame reasoning as Semax.
- 04Almost all evidence is Russian-languageIt is a registered medicine there. The studies are largely unreplicated in Western journals.
Where this compound is thought to act.
What else is it used for?
Each group carries its own evidence level.Approved means regulators have cleared it for that purpose. Investigational means it is in trials. Early research means it is being studied and is not established.
Anxiety
Clinical use- Human trialIn 62 patients with generalised anxiety, it performed similarly to a standard benzodiazepine on three anxiety scales, with less fatigue. The study was not double-blind or placebo-controlled and reported no statistics.
- RegulatoryIt is approved in Russia as a nasal spray for generalised anxiety.
Mechanism
Early research- Lab studyIt blocks the enzymes that break down natural calming molecules, prolonging their effect.
- Animal studyIt altered BDNF activity in the rat hippocampus.
- No dataWidely repeated claims of trials in hundreds of patients do not trace to any identifiable published study.
Claims of trials in 800 patients circulate widely but do not trace to any identifiable published study. The real evidence base is one 62-patient Russian trial.
The published record
70
Records indexed for Selank
16 in humans, 10 of them original studies.
2 registered trials, 0 with posted results.
FDA: Nominated but withdrawn; previously category 2.
Counted from Europe PMC indexing, not read by a person. Human means indexed under humans, which includes reviews and work on human cells. Original studies exclude reviews and lab work on human cells.Last updated 11 September 2026.
At a glance
Four things to know about Selank
Evidence
Research only
Category
Brain, mood and sleep
Common vial
30 mg
Half-life
Minutes
How much, and do you cycle it?
The range, and whether you take breaks.0.25 up to 0.5 mg per day, 1-2x daily. Taken in courses, usually 10 to 14 days, with breaks betweenCommunity practice
Course dosing follows the Russian clinical practice it comes from. No controlled study has compared it against continuous use.
How long does it stay in the body?
The half-life, and where the figure comes from.MinutesHuman study
Refers to the nasal route. The underlying work is in Russian-language journals.
Not yet traced to a primary source.
You can compare this against the whole library to see where it sits.
What does it cost?
Typical dose and cost, in plain numbers.Selank is not injected
It is taken nasal spray, or injected under the skin.
Selank starts at $20.14 across 51 vendors, typically $3.00 – $10.00 per mg.
91 listings, last read Sep 5, 2026. Shipping and card fees are not included.
How do you store it?
Before mixing, and after.Fridge after opening. Use within about 30 days.
Store sealed Selank in the fridge. Once opened, keep it upright in the fridge and plan to finish it inside roughly 30 days. Keep it out of light and do not freeze the liquid.
What are the side effects and cautions?
Known cautions and warnings for this compound.Who should avoid it
- No formal contraindications established outside Russia
- Pregnancy
Stop and get help
- Signs of an allergic reaction
Common effects
- Mild nasal irritation, stinging, or dryness, from nasal use
- An occasional metallic taste
- Brief tiredness
- No sedation, dependence, or withdrawal, unlike benzodiazepines
- Nothing is documented about injecting it
What regulators say
- FDA: Certain Bulk Drug Substances for Use in Compounding that May Present Significant Safety Risks (category 2 and withdrawn nominations), current as of April 22, 2026Nominated but withdrawn; previously category 2
Listed as Selank acetate (TP-7)
Checked 11 September 2026
Where this page says nothing is established, that means nobody has studied it, not that a compound is safe.
Is Selank approved?
And where the numbers on this page come from.No. Selank is not approved for any use, anywhere. It is sold labelled for laboratory research only, and there is no legal route to buy it for human use. It is approved in Russia, but not in the United States.
- Approval statusResearch only
- RouteNasal spray, or injected under the skin
- CheckedJuly 2026
- Approved outside the USRussia: Registered in Russia in 2009 as an intranasal solution.This does not change the United States position above.
What has happened recently
We have not yet written a full regulatory note for this compound. The status above is current as of the date shown.
You can compare this against the whole library, or read how to check a seller.
- DoseFrom research and community reports. No regulator has reviewed this dose.
- Vial sizeFrom what vendors typically list; not a recommendation.
- Sources
- Reviewed22 July 2026
What else is like Selank?
Others in Brain, mood and sleep, side by side.If you're weighing Selank, it's worth reading N-Acetyl Semax Amidate, DSIP (Delta Sleep-Inducing Peptide), and Dihexa in the same class.
A peptide that eases anxiety while keeping you clear-headed.
- Dose
- 0.25 up to 0.5 mg per day
- How often
- 1-2x daily
A longer-lasting version of Semax for focus and memory.
- Dose
- 0.2 up to 0.4 mg per day
- How often
- 1-2x daily
A before-bed peptide used to deepen sleep.
- Dose
- 0.1 up to 0.2 mg per dose (start low, increase slowly)
- How often
- Nightly
A very potent experimental peptide studied for memory and brain connections.
- Dose
- 5 up to 20 mg per day (start low, increase slowly)
- How often
- Daily
Guides for this compound
- How to Reconstitute a Peptide
Mix peptide powder with bacteriostatic water, step by step.
- How to Read an Insulin Syringe
Read the units, convert to millilitres, and draw the exact dose.
- mcg vs mg: The Peptide Dosing Mistake to Avoid
Your vial says mg and your protocol says mcg. Here is the conversion and how to check it.
- How to Read a Peptide COA
What the purity number does and does not tell you, and how to spot an edited report.
- How to Vet a Peptide Vendor
Independent COAs, HPLC purity, and the red flags that mean walk away.
Sources
- Zozulya anxiety trial, PubMed, 2008
- Selank enkephalinase mechanism, PubMed
- FDA, bulk drug substances for compounding that may present significant safety risks(2026)FDA lists selank acetate, also called TP-7. It cites immunogenicity risk for certain routes from aggregation and peptide-related impurities, and says it lacks important information about any safety issues selank raises when administered to humans. As of the 22 April 2026 version of this page, the substance sits in the second table, headed bulk drug substances nominated but withdrawn, rather than in the live category 2 list. The nomination was withdrawn, which is not the same as being approved or cleared: FDA still publishes the safety language above, and no longer has a nomination in front of it to evaluate.
Last reviewed 22 July 2026
Beyond these, 70 records are indexed. Browse the records