Pinealon_Dosage, benefits & legal status
Also known as EDR, Glu-Asp-Arg
A short bioregulator taken in courses for brain and sleep, with thin evidence.
Common vial size is what vendors typically sell, not a recommendation. Enter your own vial in the calculator.
What is Pinealon?
Plain language first. The technical label stays, but it never stands alone.Overview
It is marketed to support brain function, sleep and healthy aging. There is very little real human research behind it.
Pinealon is a 3-amino-acid 'bioregulator' from the Russian Khavinson family of short peptides.
What it's used for
A short bioregulator peptide taken in courses for brain function, sleep, and healthy aging.
How does Pinealon work?
What it does in the body, and where.Pinealon is a three-amino-acid bioregulator from the Russian Khavinson tradition, marketed for brain function and sleep.
- 01The proposal is that short peptides reach DNA directlyThe Khavinson theory holds that peptides this small enter the cell nucleus and influence which genes are read. This is not an established mechanism in mainstream molecular biology.
- 02There is no citable human evidenceNothing published outside Russian-language sources from the originating institute, and no independent replication.
What else is it used for?
Each use below carries its own evidence level. Approved means regulators have cleared it for that purpose. Investigational means it is in trials. Early research means it is being studied and is not established.
- Brain function, sleep, and healthy agingResearch only
The published record
Papers and trials about Pinealon
Searched: Pinealon.
Left out: EDR (electrodermal response, extended dynamic range); Glu-Asp-Arg (two or three residue sequence, matches generic peptide chemistry).
8 papers tagged human · 5 not reviews or lab · 1 clinical trial publications
Furthest stage reached: Published trials only, 1 clinical trial publication, no phased trial registered
Counted from Europe PMC indexing, not read by a person; a human tag can land on reviews, commentary or lab papers; clinical trial publications is the narrower count.
At a glance
Four things to know about Pinealon
Evidence
Category
Brain, mood and sleep
Common vial
10 mg
Half-life
Nothing published
How much, and do you cycle it?
The range, and whether you take breaks.1 up to 10 mg per day (start low, increase slowly), 10-20 day courses. Courses of 10 to 20 days, repeated two or three times a year Community practice
The course structure is how the Khavinson protocols specify these and how they are sold. No trial has compared course dosing against continuous use, or established how long the gap between courses should be.
Nothing publishedNo figure
No half-life has ever been published for any of the Russian bioregulator peptides, in people or in animals. The research behind them, mostly from one group in St Petersburg, measures effects on tissue, gene activity and lifespan. None of it measures how long the peptide stays in the body.
You can compare this against the whole library to see where it sits.
How do I dose and price it?
Enter your vial and your dose. Pick a mix. We show the draw and the cost.The vial holds a fixed amount of drug. Adding more water does not make more drug, it just spreads it thinner, so you draw a bigger number on the syringe for the same dose.
Choose your mix
Measuring the water1 mL = one full 100-unit syringe.
Pinealon starts at $21.44 across 90 vendors, typically $2.68 – $6.00 per mg.
115 listings, last read Oct 24, 2026. Shipping and card fees are not included.
How do you store it?
Before mixing, and after.Dry powder in the freezer or fridge. Once mixed, fridge, and use within about a month.
Unmixed lyophilized Pinealon keeps for a long time cold. Once you add water the clock starts: most reconstituted vials hold up for roughly 28 to 30 days at fridge temperature. Keep it out of light, and do not freeze it after mixing.
What are the side effects and cautions?
Known cautions and warnings for this compound.Who should avoid it
- Pregnancy or breastfeeding
- Any prescription medicine you take regularly, without checking for interactions first
- Anyone who wants established safety data, because none exists for this compound in humans
Stop and get help
- Spreading hives, swelling of the face or throat, or trouble breathing, which can happen with any injection and is a medical emergency
- Redness, heat, or pus at the injection site, which can signal infection
- Any severe or unexpected symptom
- Anything unusual, since there is no known safety profile to compare it against
Common effects
- Little human evidence exists.
- Redness, soreness, or a small bump at the injection site
- Beyond the above, unknown. There is no reliable human data on what this compound commonly causes
Where this page says nothing is established, that means nobody has studied it, not that a compound is safe.
Is Pinealon approved?
And where the numbers on this page come from.No. Pinealon is not approved for any use, anywhere. It is sold labeled for laboratory research only, and there is no legal route to buy it for human use.
- Approval statusResearch only
- RouteUnder the skin, or by mouth
- Checked14 August 2026
- DoseFrom community reports. No regulator or trial established this dose.
- Vial sizeFrom what vendors typically list; not a recommendation.
- SourcesNone traced yet.
What has happened recently
We have not yet written a full regulatory note for this compound. The status above is current as of the date shown.
You can compare this against the whole library, or read how to check a seller.
What else is like Pinealon?
Others in Brain, mood and sleep, side by side.If you're weighing Pinealon, it's worth reading Dihexa, Semax + Selank blend, and Adamax in the same class.
A short bioregulator taken in courses for brain and sleep, with thin evidence.
- Dose
- 1 up to 10 mg per day (start low, increase slowly)
- How often
- 10-20 day courses
A very potent experimental peptide studied for memory and brain connections.
- Dose
- 5 up to 20 mg per day (start low, increase slowly)
- How often
- Daily
Two Russian research peptides in one vial, sold for focus and calm together.
- Dose
- Research only
- How often
- Daily, by convention
A product name that covers at least two different molecules.
- Dose
- Research only
- How often
- No established schedule
Guides for this compound
- How to Reconstitute a Peptide
Mix peptide powder with bacteriostatic water, step by step.
- How to Read an Insulin Syringe
Read the units, convert to millilitres, and draw the exact dose.
- mcg vs mg: The Peptide Dosing Mistake to Avoid
Your vial says mg and your protocol says mcg. Here is the conversion and how to check it.
- How to Read a Peptide COA
What the purity number does and does not tell you, and how to spot an edited report.
- How to Vet a Peptide Vendor
Independent COAs, HPLC purity, and the red flags that mean walk away.
Sources
No primary source has been traced for this compound yet. Treat everything on this page as unverified until one is. How we grade evidence
Beyond these, 17 records are indexed. Browse the records