PEG-MGF_Dosage, benefits & legal status
Also known as pegylated MGF
A longer-lasting muscle-repair peptide on a less-frequent schedule.
Common vial size is what vendors typically sell, not a recommendation. Enter your own vial in the calculator.
What is PEG-MGF?
Plain language first. The technical label stays, but it never stands alone.Overview
It does the same muscle-repair job as MGF but on a less-frequent schedule.
PEG-MGF is mechano growth factor with a PEG coating that makes it last far longer in the body.
What it's used for
A longer-lasting version of the muscle-repair peptide, used on a less-frequent schedule.
How does PEG-MGF work?
What it does in the body, and where.PEG-MGF is MGF with a polyethylene glycol coating attached, a standard drug-industry technique for making a molecule last longer.
- 01Same satellite-cell activation as MGFThe active part is unchanged.
- 02The PEG coating slows clearanceTurning a minutes-long half-life into hours, so it can be injected less often.
- 03The trade is localityMGF's appeal was acting where you injected it. Making it last longer means it also spreads further, which somewhat undermines the point.
- 04No human trialsSame as MGF.
What else is it used for?
Each use below carries its own evidence level. Approved means regulators have cleared it for that purpose. Investigational means it is in trials. Early research means it is being studied and is not established.
- Muscle repair on a less frequent schedule than plain MGFResearch only
The published record
Papers and trials about PEG-MGF
Searched: PEG-MGF, pegylated MGF.
1 papers tagged human · 0 not reviews or lab · 0 clinical trial publications
Furthest stage reached: No clinical trial on record
Compare this against the whole library →
Nominated but withdrawn; previously category 2RegulatorsCounted from Europe PMC indexing, not read by a person; a human tag can land on reviews, commentary or lab papers; clinical trial publications is the narrower count.
At a glance
Four things to know about PEG-MGF
How much, and do you cycle it?
The range, and whether you take breaks.0.2 up to 0.4 mg per dose (start low, increase slowly), 1-2x per week. No established schedule No range
No published study has established how long to take this or whether a break is needed. Schedules quoted online come from vendors and forums, and different sources disagree.
How long does it stay in the body?
The half-life, and where the figure comes from.Not establishedCommunity practice
Attaching PEG to a peptide does extend how long it lasts, which is why the days-long figures sound plausible. No study has measured it.
Not yet traced to a primary source.
You can compare this against the whole library to see where it sits.
How do I dose and price it?
Enter your vial and your dose. Pick a mix. We show the draw and the cost.The vial holds a fixed amount of drug. Adding more water does not make more drug, it just spreads it thinner, so you draw a bigger number on the syringe for the same dose.
Choose your mix
Measuring the water1 mL = one full 100-unit syringe.
PEG-MGF starts at $27.30 across 42 vendors, typically $12.60 – $25.00 per mg.
47 listings, last read Oct 24, 2026. Shipping and card fees are not included.
How do you store it?
Before mixing, and after.Dry powder in the freezer or fridge. Once mixed, fridge, and use within about a month.
Unmixed lyophilized PEG-MGF keeps for a long time cold. Once you add water the clock starts: most reconstituted vials hold up for roughly 28 to 30 days at fridge temperature. Keep it out of light, and do not freeze it after mixing.
What are the side effects and cautions?
Known cautions and warnings for this compound.Solubility, computed: 46% charged residues, 12% hydrophobic. Water usually sufficient.
A first-pass rule from peptide manufacturers' guidance. It does not account for disulfide bridges, salt form or how the powder was dried, and it predicts what should be easy rather than what will happen in your vial.
Who should avoid it
- No human safety data exists, so nobody can say who should avoid it
- Pregnancy
- Active cancer, as a precaution given the growth mechanism
Stop and get help
- Anything unusual, since there is no known safety profile to compare against
- Signs of an allergic reaction such as face or throat swelling, hives, or trouble breathing
Common effects
- Unknown in humans. This compound has only been studied in cells and animals
Where this page says nothing is established, that means nobody has studied it, not that a compound is safe.
Is PEG-MGF approved?
And where the numbers on this page come from.No. PEG-MGF is not approved for any use, anywhere. It is sold labeled for laboratory research only, and there is no legal route to buy it for human use.
- Approval statusResearch only
- RouteUnder the skin (subcutaneous)
- Checked22 July 2026
- DoseFrom community reports. No regulator or trial established this dose.
- Vial sizeFrom what vendors typically list; not a recommendation.
- SourcesNone traced yet.
What has happened recently
We have not yet written a full regulatory note for this compound. The status above is current as of the date shown.
What regulators say
From official documentsNominated but withdrawn; previously category 2
FDA has not identified any human exposure data for any route
Checked 11 September 2026FDA: Certain Bulk Drug Substances for Use in Compounding that May Present Significant Safety Risks (category 2 and withdrawn nominations), current as of April 22, 2026Prohibited at all times, in and out of competition. S2.3 Growth factors and growth factor modulators: Mechano growth factors (MGFs). Non-Specified.
Checked 12 September 2026WADA: The 2026 Prohibited List (in force 1 January 2026)
Banned in drug-tested sport. Most research peptides are prohibited under WADA's S0 category, which covers any substance with no approval from any regulatory authority for human use. That means a compound can be banned without ever being named on the prohibited list. Check with your own anti-doping authority rather than assuming absence from the list means permitted.
You can compare this against the whole library, or read how to check a seller.
What else is like PEG-MGF?
Others in Muscle building, side by side.If you're weighing PEG-MGF, it's worth reading Follistatin (FST-344), MGF (Mechano Growth Factor), and ACE-031 (Ramatercept) in the same class.
A longer-lasting muscle-repair peptide on a less-frequent schedule.
- Dose
- 0.2 up to 0.4 mg per dose (start low, increase slowly)
- How often
- 1-2x per week
An experimental muscle-builder that releases the body's brake on growth.
- Dose
- Research only
- How often
- Cycled
A local muscle-repair peptide injected near a worked muscle.
- Dose
- 0.1 up to 0.2 mg per dose (start low, increase slowly)
- How often
- Post-workout
An experimental muscle-builder whose development was paused over side effects.
- Dose
- 0.02 up to 3 mg/kg per dose
- How often
- Single dose in the trial
Guides for this compound
- How to Reconstitute a Peptide
Mix peptide powder with bacteriostatic water, step by step.
- How to Read an Insulin Syringe
Read the units, convert to millilitres, and draw the exact dose.
- mcg vs mg: The Peptide Dosing Mistake to Avoid
Your vial says mg and your protocol says mcg. Here is the conversion and how to check it.
- How to Read a Peptide COA
What the purity number does and does not tell you, and how to spot an edited report.
- How to Vet a Peptide Vendor
Independent COAs, HPLC purity, and the red flags that mean walk away.
Sources
No primary source has been traced for this compound yet. Treat everything on this page as unverified until one is. How we grade evidence
Beyond these, 3 records are indexed. Browse the records