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Decoding

MGF (Mechano Growth Factor)_

Also known as mechano growth factor, IGF-1Ec

A local muscle-repair peptide injected near a worked muscle.

Muscle repairIGF-1 splice variantResearch only
InMuscle building
Common vial size2 mg
Dose0.1 up to 0.2 mg per dose (start low, increase slowly)
FrequencyPost-workout
RouteUnder the skin or into muscle
StatusResearch only
MixYour choice, calculate it
CycledNo established schedule

Common vial size is what vendors typically sell, not a recommendation. Enter your own vial in the calculator.

01

What is MGF (Mechano Growth Factor)?

Plain language first. The technical label stays, but it never stands alone.

Overview

MGF (mechano growth factor) is a variant of IGF-1 that muscles produce locally after intense exercise. In plain terms: it activates the stem cells that rebuild muscle, so it is injected near a worked muscle to speed repair.

What it's used for

A local muscle-repair peptide that helps rebuild muscle after hard training, injected near the worked muscle.

02

How does MGF (Mechano Growth Factor) work?

What it does in the body, and where.

MGF is a variant of IGF-1 that your muscles produce themselves after hard training. It is a repair signal, not a growth hormone.

  1. 01
    Muscle makes it in response to mechanical stress
    Hence the name: mechano growth factor.
  2. 02
    It activates satellite cells
    The stem cells that sit alongside muscle fibres and are recruited to rebuild them after damage.
  3. 03
    It clears within minutes
    Which is why it is injected close to the muscle worked, and why the pegylated version exists.
  4. 04
    Human evidence is essentially absent
    The physiology is established. Injecting it as a supplement is not studied.
Where it acts
Muscle

Where this compound is thought to act.

03

What else is it used for?

Each use below carries its own evidence level. Approved means regulators have cleared it for that purpose. Investigational means it is in trials. Early research means it is being studied and is not established.

  • Repairing muscle after hard training, injected near the worked muscleResearch only
04

How much, and do you cycle it?

The range, and whether you take breaks.

0.1 up to 0.2 mg per dose (start low, increase slowly), post-workout. No established scheduleNo range

No published study has established how long to take this or whether a break is needed. Schedules quoted online come from vendors and forums, and different sources disagree.

Compare cycling across compounds →

05

How do I dose and price it?

Enter your vial and your dose. Pick a mix. We show the draw and the cost.

The vial holds a fixed amount of drug. Adding more water does not make more drug, it just spreads it thinner, so you draw a bigger number on the syringe for the same dose.

Your vial size (mg)
Printed on the vial.
What you paid per vial
$
Used for cost per dose only.
Your dose (mcg)
Commonly referenced range: 0.1 up to 0.2 mg per dose (start low, increase slowly)Community practice

Choose your mix

your own mL
units · —
Enter your own volume

Measuring the water1 mL = one full 100-unit syringe.

Your draw

10 / 100 units
Full calculator with reorder date →Read a syringe →
06

How do you store it?

Before mixing, and after.

Dry powder in the freezer or fridge. Once mixed, fridge, and use within about a month.

Unmixed lyophilized MGF (Mechano Growth Factor) keeps for a long time cold. Once you add water the clock starts: most reconstituted vials hold up for roughly 28 to 30 days at fridge temperature. Keep it out of light, and do not freeze it after mixing.

07

What are the side effects and cautions?

Known cautions and warnings for this compound.

Who should avoid it

Check these before anything else.
  • No human safety data exists, so nobody can say who should avoid it
  • Pregnancy
  • Active cancer, as a precaution given the growth mechanism

Stop and get help

These are emergencies. Seek care.
  • Anything unusual, since there is no known safety profile to compare against
  • Signs of an allergic reaction such as face or throat swelling, hives, or trouble breathing

Common effects

Expected, and usually mild.
  • Unknown in humans. This compound has only been studied in cells and animals

Where this page says nothing is established, that means nobody has studied it, not that a compound is safe.

08

Is MGF (Mechano Growth Factor) approved?

And where the numbers on this page come from.
Research only

No. Not FDA-approved.

Sold for research use only. Not cleared for human consumption or medical use.

  • DoseFrom research and community reports. No regulator has reviewed this dose.
  • Vial sizeFrom what vendors typically list; not a recommendation.
  • Reviewed22 July 2026
09

What else is like MGF (Mechano Growth Factor)?

Others in Muscle building, side by side.

If you're weighing MGF (Mechano Growth Factor), it's worth reading Bimagrumab, Ipamorelin + CJC-1295 blend, and IGF-1 LR3 in the same class.

YOU ARE HERE
MGF (Mechano Growth Factor)

A local muscle-repair peptide injected near a worked muscle.

Research only
Dose
0.1 up to 0.2 mg per dose (start low, increase slowly)
How often
Post-workout
BIMA300 residues
Bimagrumab

An experimental shot that strips fat while adding muscle.

Investigational
Dose
10 up to 30 mg/kg per month (trial doses)
How often
Monthly
IPA+CJCBlend
Ipamorelin + CJC-1295 blend

The popular growth-hormone combo in one shot, for muscle, recovery, and sleep.

Research only
Dose
~100 mcg CJC + 200-300 mcg ipa
How often
Daily, often at night
LR383 residues
IGF-1 LR3

A powerful muscle-builder that also drops blood sugar hard.

Research only
Dose
0.02 up to 0.05 mg per day (start low, increase slowly)
How often
Daily, cycled
Browse the full muscle-building lineup
10

What these words mean

Show glossary +
Titrate
Starting at a low dose and increasing it slowly over time so your body adjusts and side effects stay mild.
Subcutaneous
An injection just under the skin, into the fat layer, usually with a short, thin insulin needle.
Intramuscular (IM)
An injection into a muscle, using a longer needle.
Reconstitution
Mixing a powdered peptide with liquid (bacteriostatic water) so it can be drawn into a syringe.
Bacteriostatic water
Sterile water with a tiny amount of preservative, used to mix powdered peptides.
Concentration
How strong the mixed peptide is, in milligrams per milliliter (mg/mL). More water makes it weaker; less water makes it stronger.
Units (on the syringe)
The marks on an insulin syringe. 100 units equals 1 mL. They measure how much liquid you draw, not the dose in milligrams.
mcg and mg
Units of dose. 1 milligram (mg) equals 1,000 micrograms (mcg).
GLP-1
A natural gut hormone that lowers appetite and blood sugar. Drugs that copy it, like semaglutide, are used for weight loss.
Growth hormone secretagogue
A compound that nudges your body to release more of its own growth hormone, rather than injecting the hormone itself.
Half-life
How long a compound stays active in your body. A longer half-life means you inject less often.
Peptide vs small molecule
A peptide is a short chain of amino acids. A few items here (like MK-677 or methylene blue) are small molecules, not true peptides, but people use them the same way.
Research only
No approved dose or use in people. Sold for research and not reviewed by the FDA for safety or quality.
Investigational
Still being tested in clinical trials and not yet approved or legally sold for general use.
Banned in drug-tested sport
Prohibited by the World Anti-Doping Agency (WADA); using it can disqualify a competing athlete.

Last reviewed 22 July 2026