Pemvidutide_Dosage, benefits & legal status
Also known as ALT-801
An experimental weekly shot for weight loss and fatty liver.
Common vial size is what vendors typically sell, not a recommendation. Enter your own vial in the calculator.
What is Pemvidutide?
Plain language first. The technical label stays, but it never stands alone.Overview
What it's used for
An experimental weekly shot for weight loss and fatty-liver disease, working on two pathways.
How does Pemvidutide work?
What it does in the body, and where.Pemvidutide combines GLP-1 with glucagon, and is being developed for liver disease as much as for weight.
- 01GLP-1 reduces intake, glucagon raises expenditureThe same two-lever design as survodutide.
- 02Liver fat is the primary targetGlucagon acts directly on the liver, which is why this pairing keeps being tested in fatty liver disease rather than only in obesity.
- 03Still investigationalPhase 2 results only.
What else is it used for?
Each use below carries its own evidence level. Approved means regulators have cleared it for that purpose. Investigational means it is in trials. Early research means it is being studied and is not established.
- Weight lossInvestigational
- Fatty liver disease (MASH)Investigational
The published record
Papers and trials about Pemvidutide
Searched: pemvidutide, ALT-801.
25 papers tagged human · 6 not reviews or lab · 3 clinical trial publications
16 registered trials · 5 with posted results
Furthest stage reached: Phase 3, under way
Counted from Europe PMC indexing, not read by a person; a human tag can land on reviews, commentary or lab papers; clinical trial publications is the narrower count.
At a glance
Four things to know about Pemvidutide
Evidence
Investigational
Category
Weight loss and metabolic
Common vial
10 mg
Half-life
About 110 hours
How much, and do you cycle it?
The range, and whether you take breaks.1.2 up to 2.4 mg per week (trial doses), weekly. Not cycled in the trials Trial dose
Given continuously for the whole study period: MOMENTUM, 48 weeks. The dose is stepped up at the start, which is a ramp rather than a cycle, and no trial in this class built in a planned break.
About 110 hoursTrial protocol
From an investor presentation rather than a published pharmacokinetic paper.
Source: Altimmune phase 1 corporate disclosure, September 2021. ADA 2022 abstract 334-OR
You can compare this against the whole library to see where it sits.
How do I dose and price it?
Enter your vial and your dose. Pick a mix. We show the draw and the cost.The vial holds a fixed amount of drug. Adding more water does not make more drug, it just spreads it thinner, so you draw a bigger number on the syringe for the same dose.
Choose your mix
Measuring the water1 mL = one full 100-unit syringe.
How do you store it?
Before mixing, and after.Dry powder in the freezer or fridge. Once mixed, fridge, and use within about a month.
Unmixed lyophilized Pemvidutide keeps for a long time cold. Once you add water the clock starts: most reconstituted vials hold up for roughly 28 to 30 days at fridge temperature. Keep it out of light, and do not freeze it after mixing.
What are the side effects and cautions?
Known cautions and warnings for this compound.Solubility, computed: 31% charged residues, 34% hydrophobic. Water usually sufficient.
A first-pass rule from peptide manufacturers' guidance. It does not account for disulfide bridges, salt form or how the powder was dried, and it predicts what should be easy rather than what will happen in your vial.
Who should avoid it
- No formal contraindications established
- Pregnancy
Stop and get help
- Vomiting that will not stop
- Severe stomach pain that spreads to your back
- Signs of an allergic reaction such as face or throat swelling, hives, or trouble breathing
Common effects
- Nausea and vomiting are the main effects, mostly mild to moderate
- Low rates of diarrhea and constipation
- The manufacturer reports no meaningful rise in heart rate, which is a company-reported claim
Where this page says nothing is established, that means nobody has studied it, not that a compound is safe.
Is Pemvidutide approved?
And where the numbers on this page come from.No. Pemvidutide is not approved anywhere and is currently in company-run clinical trials. There is no legal route to obtain it outside a trial.
- Approval statusInvestigational
- RouteUnder the skin (subcutaneous)
- Checked22 July 2026
- DoseFrom published clinical trials. Not approved by a regulator for this dose.
- Vial sizeFrom what vendors typically list; not a recommendation.
- SourcesNone traced yet.
What has happened recently
We have not yet written a full regulatory note for this compound. The status above is current as of the date shown.
You can compare this against the whole library, or read how to check a seller.
What else is like Pemvidutide?
Others in GLP-1 agonists, side by side.If you're weighing Pemvidutide, it's worth reading Ribupatide, VK2735, and Zabopegdutide (DD01) in the same class.
An experimental weekly shot for weight loss and fatty liver.
- Dose
- 1.2 up to 2.4 mg per week (trial doses)
- How often
- Weekly
An experimental weekly GLP-1/GIP shot from China, now in a 4,900-person phase 3 program.
- Dose
- 2 up to 10 mg per week (trial doses)
- How often
- Weekly
An experimental weight-loss compound in the tirzepatide family, as a shot or pill.
- Dose
- 2.5 up to 15 mg per week (start low, increase slowly)
- How often
- Weekly
Nearly the same peptide as efinopegdutide, carried on a large PEG instead of an antibody fragment. In a 67-person phase 2, 76% on the drug cut liver fat by at least 30% in 12 weeks, against 12% on placebo.
- Dose
- 20 mg weekly for 2 weeks, then 40 mg weekly (phase 2 trial)
- How often
- Weekly
Guides for this compound
- How to Reconstitute a Peptide
Mix peptide powder with bacteriostatic water, step by step.
- How to Read an Insulin Syringe
Read the units, convert to millilitres, and draw the exact dose.
- mcg vs mg: The Peptide Dosing Mistake to Avoid
Your vial says mg and your protocol says mcg. Here is the conversion and how to check it.
- How to Read a Peptide COA
What the purity number does and does not tell you, and how to spot an edited report.
- How to Vet a Peptide Vendor
Independent COAs, HPLC purity, and the red flags that mean walk away.
Sources
No primary source has been traced for this compound yet. Treat everything on this page as unverified until one is. How we grade evidence
Beyond these, 36 records are indexed. Browse the records