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N-Acetyl Semax Amidate_Dosage, benefits & legal status

Also known as NA Semax Amidate, NASA Semax

Published July 22, 2026 · Updated July 25, 2026

A longer-lasting version of Semax for focus and memory.

Focus & brainSemax variantResearch only
Common vial size30 mg
Dose0.2 up to 0.4 mg per day
Frequency1-2x daily
RouteNasal spray, or injected under the skin
StatusResearch only
CycledTaken in courses, usually 10 to 14 days, with breaks between

Common vial size is what vendors typically sell, not a recommendation. Enter your own vial in the calculator.

01

What is N-Acetyl Semax Amidate?

Plain language first. The technical label stays, but it never stands alone.

Overview

It does the same focus-and-memory job by raising BDNF, but resists breakdown so it lasts longer.

The technical version

N-Acetyl Semax Amidate is a chemically tweaked, more stable version of Semax.

What it's used for

A longer-lasting, more stable version of Semax for focus, memory, and mental clarity.

02

How does N-Acetyl Semax Amidate work?

What it does in the body, and where.

This is Semax with two chemical modifications, an acetyl group at one end and an amide at the other, both added to slow its breakdown.

  1. 01
    Same BDNF mechanism as Semax
    Nothing about the target changes.
  2. 02
    The modifications resist enzymes
    Which extends how long it stays active after a dose.
  3. 03
    Even less studied than Semax
    Semax has decades of Russian clinical use behind it. This variant does not, and is largely a vendor product.
Where it acts
Brain

Where this compound is thought to act.

03

What else is it used for?

Each use below carries its own evidence level. Approved means regulators have cleared it for that purpose. Investigational means it is in trials. Early research means it is being studied and is not established.

  • Focus, memory, and mental clarity, as a longer-lasting version of SemaxResearch only
  • Lasting longer per dose than plain Semax, which is the reason to choose itResearch only

The published record

Research index

0

Records indexed for N-Acetyl Semax Amidate

Europe PMC was searched on 11 September 2026 and returned nothing.

Counted from Europe PMC indexing, not read by a person.

N-Acetyl Semax Amidate vial rendering
Compound field notes

At a glance

Four things to know about N-Acetyl Semax Amidate

01

Evidence

Research only

02

Category

Brain, mood and sleep

03

Common vial

30 mg

04

Half-life

Not established

04

How much, and do you cycle it?

The range, and whether you take breaks.

0.2 up to 0.4 mg per day, 1-2x daily. Taken in courses, usually 10 to 14 days, with breaks betweenCommunity practice

Same course pattern as Semax, which it is a longer-lasting version of. No controlled study has compared courses against continuous use.

Compare this against the whole library →

05

How long does it stay in the body?

The half-life, and where the figure comes from.

Not establishedCommunity practice

The modified version has not been characterised at all. Even plain semax rests on Russian-language work that reports effects rather than clearance.

Not yet traced to a primary source.

You can compare this against the whole library to see where it sits.

06

What does it cost?

Typical dose and cost, in plain numbers.

N-Acetyl Semax Amidate is not injected

It is taken nasal spray, or injected under the skin.

Cost per month
Cost per dose
Typical dose
200 mcg–400 mcg / dayCommunity practice
No published human study establishes this dose. It comes from vendor and community practice, and several compounds in this group share suspiciously identical round numbers across retailer sites.
What it costs

N-Acetyl Semax Amidate starts at $64.97 across 4 vendors, typically $2.97 – $3.25 per mg.

6 listings, last read Sep 5, 2026. Shipping and card fees are not included.

See all 6 listings →
07

How do you store it?

Before mixing, and after.

Fridge after opening. Use within about 30 days.

Store sealed N-Acetyl Semax Amidate in the fridge. Once opened, keep it upright in the fridge and plan to finish it inside roughly 30 days. Keep it out of light and do not freeze the liquid.

08

What are the side effects and cautions?

Known cautions and warnings for this compound.

Who should avoid it

Check these before anything else.
  • No formal contraindications established outside Russia
  • Pregnancy

Stop and get help

These are emergencies. Seek care.
  • No serious adverse events have been reported at studied doses
  • Signs of an allergic reaction

Common effects

Expected, and usually mild.
  • Mild nasal irritation, from nasal use
  • Occasional short-lived headache
  • Possible difficulty sleeping if taken late in the day
  • No tolerance, dependence, or withdrawal has been documented
  • Nothing is documented about injecting it
  • This is a modified, longer-lasting version of Semax, so its safety is inferred from Semax rather than measured separately.

Where this page says nothing is established, that means nobody has studied it, not that a compound is safe.

09

Is N-Acetyl Semax Amidate approved?

And where the numbers on this page come from.

No. N-Acetyl Semax Amidate is not approved for any use, anywhere. It is sold labelled for laboratory research only, and there is no legal route to buy it for human use.

  • Approval status
    Research only
  • Route
    Nasal spray, or injected under the skin
  • Checked
    July 2026

What has happened recently

We have not yet written a full regulatory note for this compound. The status above is current as of the date shown.

You can compare this against the whole library, or read how to check a seller.


Guides for this compound

Sources

  • FDA, bulk drug substances nominated for use in compounding under section 503A, updated 14 May 2026(2026)
    Read this against what FDA did with Semax itself, which went before the agency's Pharmacy Compounding Advisory Committee in July 2026. This compound is not Semax. It is an acetylated amide derivative, and FDA treats even a free base and its acetate salt as different active ingredients with potentially different safety profiles. It appears in none of the three categories on this list. This list is the comprehensive record of what has been proposed for pharmacy compounding since the process opened in 2013, when over two thousand substances were nominated, so absence from all three categories means no one has ever put this compound forward.

Last reviewed 22 July 2026