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N-Acetyl Semax Amidate_

Also known as NA Semax Amidate, NASA Semax

A longer-lasting version of Semax for focus and memory.

Focus & brainSemax variant (nasal)Research only
InBrain, mood and sleepTaken without a needle
Common vial size30 mg
Dose0.2 up to 0.4 mg per day
Frequency1-2x daily
RouteNasal spray
StatusResearch only
MixYour choice, calculate it
CycledTaken in courses, usually 10 to 14 days, with breaks between

Common vial size is what vendors typically sell, not a recommendation. Enter your own vial in the calculator.

01

What is N-Acetyl Semax Amidate?

Plain language first. The technical label stays, but it never stands alone.

Overview

N-Acetyl Semax Amidate is a chemically tweaked, more stable version of Semax. In plain terms: it does the same focus-and-memory job by raising BDNF, but resists breakdown so it lasts longer.

What it's used for

A longer-lasting, more stable version of Semax for focus, memory, and mental clarity.

02

How does N-Acetyl Semax Amidate work?

What it does in the body, and where.

This is Semax with two chemical modifications, an acetyl group at one end and an amide at the other, both added to slow its breakdown.

  1. 01
    Same BDNF mechanism as Semax
    Nothing about the target changes.
  2. 02
    The modifications resist enzymes
    Which extends how long it stays active after a dose.
  3. 03
    Even less studied than Semax
    Semax has decades of Russian clinical use behind it. This variant does not, and is largely a vendor product.
Where it acts
Brain

Where this compound is thought to act.

03

What else is it used for?

Each use below carries its own evidence level. Approved means regulators have cleared it for that purpose. Investigational means it is in trials. Early research means it is being studied and is not established.

  • Focus, memory, and mental clarity, as a longer-lasting version of SemaxResearch only
  • Lasting longer per dose than plain Semax, which is the reason to choose itResearch only
04

How much, and do you cycle it?

The range, and whether you take breaks.

0.2 up to 0.4 mg per day, 1-2x daily. Taken in courses, usually 10 to 14 days, with breaks betweenCommunity practice

Same course pattern as Semax, which it is a longer-lasting version of. No controlled study has compared courses against continuous use.

Compare cycling across compounds →

05

How do I dose and price it?

Enter your vial and your dose. Pick a mix. We show the draw and the cost.

The vial holds a fixed amount of drug. Adding more water does not make more drug, it just spreads it thinner, so you draw a bigger number on the syringe for the same dose.

N-Acetyl Semax Amidate is not injected

It is taken nasal spray.

Cost per month
—
Cost per dose
—
Typical dose
200 mcg–400 mcg / dayCommunity practice
No published human study establishes this dose. It comes from vendor and community practice, and several compounds in this group share suspiciously identical round numbers across retailer sites.
06

How do you store it?

Before mixing, and after.

Fridge after opening. Use within about 30 days.

Store sealed N-Acetyl Semax Amidate in the fridge. Once opened, keep it upright in the fridge and plan to finish it inside roughly 30 days. Keep it out of light and do not freeze the liquid.

07

What are the side effects and cautions?

Known cautions and warnings for this compound.

Who should avoid it

Check these before anything else.
  • No formal contraindications established outside Russia
  • Pregnancy

Stop and get help

These are emergencies. Seek care.
  • No serious adverse events have been reported at studied doses
  • Signs of an allergic reaction

Common effects

Expected, and usually mild.
  • Mild nasal irritation
  • Occasional short-lived headache
  • Possible difficulty sleeping if taken late in the day
  • No tolerance, dependence, or withdrawal has been documented
  • This is a modified, longer-lasting version of Semax, so its safety is inferred from Semax rather than measured separately.

Where this page says nothing is established, that means nobody has studied it, not that a compound is safe.

08

Is N-Acetyl Semax Amidate approved?

And where the numbers on this page come from.
Research only

No. Not FDA-approved.

Sold for research use only. Not cleared for human consumption or medical use.

  • DoseFrom research and community reports. No regulator has reviewed this dose.
  • Vial sizeFrom what vendors typically list; not a recommendation.
  • Reviewed22 July 2026
09

What else is like N-Acetyl Semax Amidate?

Others in Brain, mood and sleep, side by side.

If you're weighing N-Acetyl Semax Amidate, it's worth reading Semax, Selank, and DSIP (Delta Sleep-Inducing Peptide) in the same class.

YOU ARE HERE
N-Acetyl Semax Amidate

A longer-lasting version of Semax for focus and memory.

Research only
Dose
0.2 up to 0.4 mg per day
How often
1-2x daily
Semax

A nasal spray for sharper focus, memory, and mental clarity.

Research only
Dose
0.2 up to 0.6 mg per day
How often
1-2x daily
Selank

A nasal spray that eases anxiety while keeping you clear-headed.

Research only
Dose
0.25 up to 0.5 mg per day
How often
1-2x daily
DSIP (Delta Sleep-Inducing Peptide)

A before-bed peptide used to deepen sleep.

Research only
Dose
0.1 up to 0.2 mg per dose (start low, increase slowly)
How often
Nightly
Browse peptides for focus, mood, and sleep Compare oral, nasal, and topical peptides
10

What these words mean

Show glossary +
Titrate
Starting at a low dose and increasing it slowly over time so your body adjusts and side effects stay mild.
Subcutaneous
An injection just under the skin, into the fat layer, usually with a short, thin insulin needle.
Intramuscular (IM)
An injection into a muscle, using a longer needle.
Reconstitution
Mixing a powdered peptide with liquid (bacteriostatic water) so it can be drawn into a syringe.
Bacteriostatic water
Sterile water with a tiny amount of preservative, used to mix powdered peptides.
Concentration
How strong the mixed peptide is, in milligrams per milliliter (mg/mL). More water makes it weaker; less water makes it stronger.
Units (on the syringe)
The marks on an insulin syringe. 100 units equals 1 mL. They measure how much liquid you draw, not the dose in milligrams.
mcg and mg
Units of dose. 1 milligram (mg) equals 1,000 micrograms (mcg).
GLP-1
A natural gut hormone that lowers appetite and blood sugar. Drugs that copy it, like semaglutide, are used for weight loss.
Growth hormone secretagogue
A compound that nudges your body to release more of its own growth hormone, rather than injecting the hormone itself.
Half-life
How long a compound stays active in your body. A longer half-life means you inject less often.
Peptide vs small molecule
A peptide is a short chain of amino acids. A few items here (like MK-677 or methylene blue) are small molecules, not true peptides, but people use them the same way.
Research only
No approved dose or use in people. Sold for research and not reviewed by the FDA for safety or quality.
Investigational
Still being tested in clinical trials and not yet approved or legally sold for general use.
Banned in drug-tested sport
Prohibited by the World Anti-Doping Agency (WADA); using it can disqualify a competing athlete.

Last reviewed 22 July 2026