N-Acetyl Semax_Dosage, benefits & legal status
Also known as NA Semax, Acetyl Semax, N-acetyl semax peptide
Semax with one stabilising tweak, sitting between plain Semax and the amidate version.
Common vial size is what vendors typically sell, not a recommendation. Enter your own vial in the calculator.
What is N-Acetyl Semax?
Plain language first. The technical label stays, but it never stands alone.Overview
It aims to do the same focus-and-memory job as Semax, through the same BDNF pathway, while lasting a little longer per dose.
N-Acetyl Semax is Semax with an acetyl group attached to the N-terminus, added to slow enzymatic breakdown.
What it's used for
Focus, memory, and mental clarity, as a somewhat longer-lasting version of Semax.
How does N-Acetyl Semax work?
What it does in the body, and where.This is Semax with one chemical modification, an acetyl group at the N-terminus, added to slow its breakdown.
- 01Same BDNF mechanism as SemaxNothing about the target changes.
- 02The acetyl group resists enzymesWhich should extend how long it stays active, though this has never been measured formally for this variant.
- 03Less studied than SemaxSemax has decades of Russian clinical use behind it. This variant is largely a vendor product.
What else is it used for?
Each use below carries its own evidence level. Approved means regulators have cleared it for that purpose. Investigational means it is in trials. Early research means it is being studied and is not established.
- Focus, memory, and mental clarity, the same job as SemaxResearch only
- Lasting a little longer per dose than plain Semax, which is the claimed reason for the acetyl groupResearch only
The published record
0
Papers and trials about N-Acetyl Semax
Searched: N-acetyl semax, N-acetyl-semax, acetyl semax, acetyl-semax, NA-Semax, NA Semax.
Europe PMC was searched on 25 October 2026 for these terms and returned nothing.
Counted from Europe PMC indexing, not read by a person.
At a glance
Four things to know about N-Acetyl Semax
How much, and do you cycle it?
The range, and whether you take breaks.0.2 up to 0.4 mg per day, 1-2x daily. Taken in courses, usually 10 to 14 days, with breaks between Community practice
Same course pattern as Semax, which it is a variant of. No controlled study has compared courses against continuous use.
Not establishedCommunity practice
This variant has not been characterized at all. Even plain semax rests on Russian-language work that reports effects rather than clearance.
Not yet traced to a primary source.
You can compare this against the whole library to see where it sits.
What does it cost?
Typical dose and cost, in plain numbers.The products priced here are not injected
Route: nasal spray.
N-Acetyl Semax starts at $36.59 across 14 vendors, typically $2.08 – $4.42 per mg.
19 listings, last read Oct 24, 2026. Shipping and card fees are not included.
How do you store it?
Before mixing, and after.Fridge after opening. Use within about 30 days.
Store sealed N-Acetyl Semax in the fridge. Once opened, keep it upright in the fridge and plan to finish it inside roughly 30 days. Keep it out of light and do not freeze the liquid.
What are the side effects and cautions?
Known cautions and warnings for this compound.Solubility, computed: 43% charged residues, 57% hydrophobic. Water usually sufficient.
A first-pass rule from peptide manufacturers' guidance. It does not account for disulfide bridges, salt form or how the powder was dried, and it predicts what should be easy rather than what will happen in your vial.
Who should avoid it
- No formal contraindications established outside Russia
- Pregnancy
Stop and get help
- No serious adverse events have been reported at studied doses of Semax itself
- Signs of an allergic reaction
Common effects
- Mild nasal irritation, from nasal use
- Occasional short-lived headache
- Possible difficulty sleeping if taken late in the day
- No tolerance, dependence, or withdrawal has been documented for Semax
- Almost everything known about this variant is extrapolated from Semax, not measured directly
Where this page says nothing is established, that means nobody has studied it, not that a compound is safe.
Is N-Acetyl Semax approved?
And where the numbers on this page come from.No. N-Acetyl Semax is not approved for any use, anywhere. It is sold labeled for laboratory research only, and there is no legal route to buy it for human use.
- Approval statusResearch only
- RouteNasal spray
- Checked12 September 2026
- DoseFrom community reports. No regulator or trial established this dose.
- Vial sizeFrom what vendors typically list; not a recommendation.
- Sources
What has happened recently
We have not yet written a full regulatory note for this compound. The status above is current as of the date shown.
You can compare this against the whole library, or read how to check a seller.
What else is like N-Acetyl Semax?
Others in Brain, mood and sleep, side by side.If you're weighing N-Acetyl Semax, it's worth reading Adalank, Noopept (Omberacetam), and N-Acetyl Selank in the same class.
Semax with one stabilising tweak, sitting between plain Semax and the amidate version.
- Dose
- 0.2 up to 0.4 mg per day
- How often
- 1-2x daily
A Selank-family name whose sellers mostly do not say what is in it.
- Dose
- Research only
- How often
- No established schedule
A Russian memory drug sold as a supplement in the US, where selling it is unlawful.
- Dose
- 10 up to 30 mg per day (start low, increase slowly)
- How often
- 1-2x daily
Selank with one end capped rather than both, and no study of its own.
- Dose
- Research only
- How often
- No established schedule
Guides for this compound
- mcg vs mg: The Peptide Dosing Mistake to Avoid
Your vial says mg and your protocol says mcg. Here is the conversion and how to check it.
- How to Read a Peptide COA
What the purity number does and does not tell you, and how to spot an edited report.
- How to Vet a Peptide Vendor
Independent COAs, HPLC purity, and the red flags that mean walk away.
Sources
- FDA, bulk drug substances nominated for use in compounding under section 503A, updated 14 May 2026(2026)This compound is not Semax. It is an acetylated derivative, and FDA treats even a free base and its salt as different active ingredients with potentially different safety profiles. It appears in none of the three categories on this list, which is the comprehensive record of what has been proposed for pharmacy compounding since the process opened in 2013, so absence from all three categories means no one has ever put this compound forward.