Noopept (Omberacetam)_Dosage, benefits & legal status
Also known as Noopept, Omberacetam, GVS-111, SGS-111, N-phenylacetyl-L-prolylglycine ethyl ester
A Russian memory drug sold as a supplement in the US, where selling it is unlawful.
Common vial size is what vendors typically sell, not a recommendation. Enter your own vial in the calculator.
What is Noopept (Omberacetam)?
Plain language first. The technical label stays, but it never stands alone.Overview
It is a memory and focus drug. It gets sold beside peptides like Semax and Selank because it came out of the same Russian research world.
Noopept is a small molecule built from two amino acids joined together, made in Russia in 1996. It is not really a peptide: it is swallowed, absorbed like an ordinary drug, and broken down into a different active compound in the body.
What it's used for
Taken by mouth for memory, focus, and mental clarity, often after a head injury or stroke in Russia.
How does Noopept (Omberacetam) work?
What it does in the body, and where.Noopept is a starter compound. What you swallow is not what acts on your brain.
- 01It is absorbed fast and changed on the wayBlood levels peak within about fifteen to twenty minutes, and the body converts it into a different compound called cycloprolylglycine.
- 02That compound raises brain growth factorsIn animals it increased BDNF and NGF, two proteins that help brain cells form and keep connections.
- 03It also touches the receptors involved in learningIt changes how the glutamate system behaves, which is the signaling that memory formation depends on.
- 04The human evidence is thin and mostly in one languageIt has real human trials, which puts it ahead of most nootropics sold online. Those trials are small, mostly Russian, and were run in people recovering from brain injury rather than healthy people looking for an edge.
Where this compound is thought to act.
What else is it used for?
Each use below carries its own evidence level. Approved means regulators have cleared it for that purpose. Investigational means it is in trials. Early research means it is being studied and is not established.
- Memory and thinking after a stroke or head injury, which is its approved use in RussiaClinical use
- Everyday focus and memory in healthy people, which has not been properly testedResearch only
- Protecting brain cells from damage, shown in cells and animalsEarly research
The published record
Papers and trials about Noopept (Omberacetam)
29 papers tagged human · 21 not reviews or lab · 3 clinical trial publications
Furthest stage reached: Approved outside the US, Russia
Counted from Europe PMC indexing, not read by a person; a human tag can land on reviews, commentary or lab papers; clinical trial publications is the narrower count.
At a glance
Four things to know about Noopept (Omberacetam)
Evidence
Category
Brain, mood and sleep
Common vial
Varies
Half-life
About 23 minutes
How much, and do you cycle it?
The range, and whether you take breaks.10 up to 30 mg per day (start low, increase slowly), 1-2x daily. Usually taken in courses of about 8 weeks, then stopped Clinical use
Russian prescribing uses courses rather than continuous use. No study has looked at taking it for longer than a few months.
About 23 minutesHuman study
From the Russian product information rather than a peer-reviewed Western study. An active breakdown product lasts longer than the parent.
Source: Russian registered prescribing information. Rat work, Bull Exp Biol Med 2000, PMID 30378564
You can compare this against the whole library to see where it sits.
What does it cost?
Typical dose and cost, in plain numbers.Noopept (Omberacetam) is not injected
It is taken by mouth (oral).
Noopept (Omberacetam) starts at $24.99 across 4 vendors.
4 listings, last read Oct 10, 2026. Shipping and card fees are not included.
How do you store it?
Before mixing, and after.Room temperature. Cool, dry, out of light.
Noopept (Omberacetam) is taken as a pill or capsule. Keep it in its original container at room temperature, away from heat, humidity, and direct sun. No fridge or mixing needed. Check the expiration date on the bottle.
What are the side effects and cautions?
Known cautions and warnings for this compound.It is taken by mouth, so there is nothing to mix and no syringe. Doses are usually 10 mg once or twice a day. Two things worth knowing: it is often sold as a dietary supplement in the US, and that is not legal, so what is in the bottle has nobody checking it. And no study has looked at what taking it for years does.
Who should avoid it
- Pregnancy or breastfeeding
- Severe kidney or liver problems
- Under 18
- Known allergy to it
Stop and get help
- A rash or hives
- Rising blood pressure
- Sleep problems that do not settle when you lower the dose
Common effects
- Headache, which is the most commonly reported effect
- Trouble sleeping if taken late in the day
- Irritability
- Raised blood pressure in some people
- A trial of 53 people over 56 days reported fewer side effects than the older drug it was compared against
Where this page says nothing is established, that means nobody has studied it, not that a compound is safe.
Is Noopept (Omberacetam) approved?
And where the numbers on this page come from.Not in the United States. Noopept (Omberacetam) has no FDA approval and is sold there labeled for laboratory research only, so there is no legal route to buy it for human use. It is approved in Russia.
- Approval statusResearch only
- RouteBy mouth (oral)
- Checked22 September 2026
- Approved outside the USRussia: Registered in Russia as a prescription nootropic tablet. Not approved in the US.This does not change the United States position above.
- DoseFrom product labeling and clinical guidelines.
- Vial sizeFrom what vendors typically list; not a recommendation.
- Sources
What has happened recently
Approved as a prescription medicine in Russia in 2006, for memory and thinking problems after a stroke or head injury. In the United States the FDA treats it as an unapproved new drug, which means putting it in a supplement or a food is against the law, and the agency has sent warning letters to companies doing exactly that. In Australia it is prescription-only. Being easy to buy online is not the same as being legal to sell.
You can compare this against the whole library, or read how to check a seller.
What else is like Noopept (Omberacetam)?
Others in Brain, mood and sleep, side by side.If you're weighing Noopept (Omberacetam), it's worth reading Adamax 1032, Adamax 984, and CMS-121 in the same class.
A Russian memory drug sold as a supplement in the US, where selling it is unlawful.
- Dose
- 10 up to 30 mg per day (start low, increase slowly)
- How often
- 1-2x daily
The adamantane form of Adamax, identified by its weight rather than by any published study.
- Dose
- Research only
- How often
- No established schedule
A second molecule sold as Adamax: acetylated Semax with two amino acids added and no adamantane.
- Dose
- Research only
- How often
- No established schedule
A fisetin derivative from Salk, in humans since 2022 with no results published.
- Dose
- No established human dose
- How often
- No established schedule
Guides for this compound
- mcg vs mg: The Peptide Dosing Mistake to Avoid
Your vial says mg and your protocol says mcg. Here is the conversion and how to check it.
- Why Does My Peptide Injection Itch or Welt
Injection-site irritation, a histamine reaction, or a true allergy, and how to tell them apart.
- How to Read a Peptide COA
What the purity number does and does not tell you, and how to spot an edited report.
- How to Vet a Peptide Vendor
Independent COAs, HPLC purity, and the red flags that mean walk away.
Sources
- NIH NCATS Inxight Drugs, omberacetam record(2026)Developed and patented in Russia in 1996, prescribed there as a nootropic. Common dose 10 to 30 mg per day.
Beyond these, 113 records are indexed. Browse the records