MitoPrime blend (NAD+ / MOTS-c / 5-Amino-1MQ)_Dosage, benefits & legal status
Also known as MitoPrime, Mito Prime, Mito blend, Mito 120, NAD+ + MOTS-c + 5-Amino-1MQ, MitoPrime blend
Three cellular-energy compounds in one 120 mg vial, only one of which is a peptide.
Common vial size is what vendors typically sell, not a recommendation. Enter your own vial in the calculator.
What is MitoPrime blend (NAD+ / MOTS-c / 5-Amino-1MQ)?
Plain language first. The technical label stays, but it never stands alone.Overview
Three angles on the same target. Two of the three are not peptides at all.
MitoPrime is a pre-mixed vial holding three compounds aimed at cell energy: NAD+ at 100 mg, MOTS-c at 10 mg, and 5-Amino-1MQ at 10 mg. The idea behind pairing them is to supply NAD+, slow down how fast the body uses it up, and switch on the pathways that spend it.
What it's used for
A cellular-energy and longevity mix in one shot, taken for energy, metabolism, and healthy aging.
How does MitoPrime blend (NAD+ / MOTS-c / 5-Amino-1MQ) work?
What it does in the body, and where.Three compounds aimed at the same target from different angles: supply NAD+, slow how fast the body loses it, and switch on the pathways that spend it. Two of the three are not peptides.
- 01NAD+ supplies the coenzyme directlyNAD+ is required for energy production and DNA repair, and levels fall with age. This is 100 of the 120 mg in the vial.
- 025-Amino-1MQ blocks the enzyme that uses NAD+ upIt inhibits NNMT, which is meant to leave more NAD+ available. It is a small molecule, not a peptide.
- 03MOTS-c activates AMPKMOTS-c is encoded in mitochondrial DNA and signals during metabolic stress. It is the only actual peptide in the vial.
- 04The logic is tidy and completely untestedNo human trial has tested any of the three, alone or together. The blend is an argument, not a finding.
A schematic of the compound's mechanism, not a diagnostic image.
What else is it used for?
Each use below carries its own evidence level. Approved means regulators have cleared it for that purpose. Investigational means it is in trials. Early research means it is being studied and is not established.
- Cellular energy and mitochondrial functionResearch only
- Fat metabolism, from the 5-Amino-1MQ portionEarly research
- Convenience, since it puts three compounds into one injectionResearch only
The published record
0
Papers and trials about MitoPrime blend (NAD+ / MOTS-c / 5-Amino-1MQ)
Europe PMC was searched on 12 October 2026 and returned nothing.
Counted from Europe PMC indexing, not read by a person.
At a glance
Four things to know about MitoPrime blend (NAD+ / MOTS-c / 5-Amino-1MQ)
Evidence
Category
Longevity and energy
Common vial
120 mg
Half-life
None of the three has a usable figure
How much, and do you cycle it?
The range, and whether you take breaks.1 up to 5 mg MOTS-c per day (the rest follows the fixed 10:1:1 ratio), daily. No established pattern, since the blend has never been studied No range
Each component is cycled differently when used alone, and the locked ratio means you cannot follow three schedules at once. Anyone running this is picking one schedule and applying it to all three.
None of the three has a usable figureNo figure
NAD+, MOTS-c and 5-Amino-1MQ. Injected NAD+ left the blood too fast for a half-life to be worked out in the only human study. MOTS-c has never been measured in a person. The 5 to 8 hours quoted for 5-Amino-1MQ is credited to a study that does not appear to exist.
You can compare this against the whole library to see where it sits.
How do I dose and price it?
Enter your vial and your dose. Pick a mix. We show the draw and the cost.The vial holds a fixed amount of drug. Adding more water does not make more drug, it just spreads it thinner, so you draw a bigger number on the syringe for the same dose.
The ratio is locked at 10:1:1. NAD+ is 100 of the 120 mg, so the total vial size tells you almost nothing about the other two.
Pick your vial to see concentrations and a draw.
Choose your mix
Measuring the water1 mL = one full 100-unit syringe.
Your draw
What one draw delivers
The same arithmetic as the calculator, worked out for the vials vendors sell.Dose anchored to MOTS-c, at the 5 to 10 mg per day people commonly cite. Each table assumes one draw per day. If you split it across more injections, divide the reading by the number of injections.
| MOTS-c dose | 1 mL water | 2 mL water | 3 mL water |
|---|---|---|---|
| 5 mg | 50.0 units
| 100.0 units
| Over 100 units: will not fit one U-100 syringe.
|
| 10 mg | 100.0 units
| Over 100 units: will not fit one U-100 syringe.
| Over 100 units: will not fit one U-100 syringe.
|
No published human study establishes a dose for this blend. The range comes from vendor and community practice, and is anchored to one component because a blend is one draw: the other components follow at whatever ratio is in your vial.
The ratio is locked, so the whole vial is one dose decision. Taking MOTS-c across its commonly cited 1 to 5 mg daily range also delivers 10 to 50 mg of NAD+ per day, which sits inside NAD+'s own usual range. The same draw delivers 1 to 5 mg of 5-Amino-1MQ, within the range people use when injecting it on its own. Nothing in this vial is being under-delivered, and the 5-Amino-1MQ portion is the one to watch.
MitoPrime blend (NAD+ / MOTS-c / 5-Amino-1MQ) starts at $68.00 across 4 vendors, typically $1.21 – $1.24 per mg.
4 listings, last read Oct 10, 2026. Shipping and card fees are not included.
How do you store it?
Before mixing, and after.Dry powder in the freezer or fridge. Once mixed, fridge, and use within about a month.
Unmixed lyophilized MitoPrime blend (NAD+ / MOTS-c / 5-Amino-1MQ) keeps for a long time cold. Once you add water the clock starts: most reconstituted vials hold up for roughly 28 to 30 days at fridge temperature. Keep it out of light, and do not freeze it after mixing.
What are the side effects and cautions?
Known cautions and warnings for this compound.Inject slowly. NAD+ makes up 100 of the 120 mg in this vial, and pushing NAD+ too fast causes flushing, warmth, and nausea. The ratio inside the vial is locked at 10:1:1, so you cannot adjust one component without changing all three.
Who should avoid it
- Pregnancy
- No human safety data exists for 5-Amino-1MQ at all, and none for the blend
- Banned in drug-tested sport, since MOTS-c is prohibited
Stop and get help
- Chest tightness or difficulty breathing during or after injecting
- Signs of an allergic reaction
- Anything unusual, given the absence of human data on this combination
Common effects
- Flushing, warmth, and nausea if injected quickly, which comes from the NAD+ portion
- Injection-site reactions
- Beyond that, unknown. No controlled human trial has tested any of these three compounds, let alone the three together
Where this page says nothing is established, that means nobody has studied it, not that a compound is safe.
Is MitoPrime blend (NAD+ / MOTS-c / 5-Amino-1MQ) approved?
And where the numbers on this page come from.No. MitoPrime blend (NAD+ / MOTS-c / 5-Amino-1MQ) is not approved for any use, anywhere. It is sold labeled for laboratory research only, and there is no legal route to buy it for human use.
- Approval statusResearch only
- RouteUnder the skin (subcutaneous)
- Checked14 August 2026
- DoseFrom community reports. No regulator or trial established this dose.
- Vial sizeFrom what vendors typically list; not a recommendation.
- SourcesNone traced yet.
What has happened recently
The name collides with an unrelated product. MitoPrime is a registered trademark for L-ergothioneine, an oral antioxidant supplement with nothing in common with this vial. Check the ingredient list rather than the name.
Banned in drug-tested sport. Most research peptides are prohibited under WADA's S0 category, which covers any substance with no approval from any regulatory authority for human use. That means a compound can be banned without ever being named on the prohibited list. Check with your own anti-doping authority rather than assuming absence from the list means permitted.
You can compare this against the whole library, or read how to check a seller.
What else is like MitoPrime blend (NAD+ / MOTS-c / 5-Amino-1MQ)?
Others in Longevity and energy, side by side.If you're weighing MitoPrime blend (NAD+ / MOTS-c / 5-Amino-1MQ), it's worth reading Klotho, ALT-711, and Orexin A in the same class.
Three cellular-energy compounds in one 120 mg vial, only one of which is a peptide.
- Dose
- 1 up to 5 mg MOTS-c per day (the rest follows the fixed 10:1:1 ratio)
- How often
- Daily
A real longevity protein, and a category where what is sold may not be it.
- Dose
- No established human dose
- How often
- No established schedule
An anti-ageing molecule from the 1990s that broke sugar-protein crosslinks in rats and disappointed in people.
- Dose
- Research only
- How often
- No established pattern
A peptide studied for wakefulness and daytime energy.
- Dose
- Research only
- How often
- As studied
Guides for this compound
- How to Reconstitute a Peptide
Mix peptide powder with bacteriostatic water, step by step.
- How to Read an Insulin Syringe
Read the units, convert to millilitres, and draw the exact dose.
- mcg vs mg: The Peptide Dosing Mistake to Avoid
Your vial says mg and your protocol says mcg. Here is the conversion and how to check it.
- Why Does My Peptide Injection Itch or Welt
Injection-site irritation, a histamine reaction, or a true allergy, and how to tell them apart.
- How to Read a Peptide COA
What the purity number does and does not tell you, and how to spot an edited report.
Sources
No primary source has been traced for this compound yet. Treat everything on this page as unverified until one is. How we grade evidence