How much water do I add to HGH Fragment 176-191?

You can reconstitute HGH Fragment 176-191 with 0.5, 1, or 2 mL of bacteriostatic water. Each option produces a different concentration and syringe draw for the same dose. Use the calculator to see which is easiest to measure.

What does HGH Fragment 176-191 cost per dose?

Cost per dose depends on vial size, price paid, and your dose. Enter your vendor's price in the HGH Fragment 176-191 calculator to see cost per dose and monthly cost.

What is the reference dose for HGH Fragment 176-191?

The commonly referenced range is 0.25 up to 0.5 mg per day (start low, increase slowly), taken daily. This is reference information, not a recommendation. Talk to a licensed clinician.

What are the side effects of HGH Fragment 176-191?

Reported side effects of HGH Fragment 176-191 include: Generally well tolerated, but weak proof it works.; Banned in drug-tested sport.. Severity and frequency vary by person and dose.

Who should not take HGH Fragment 176-191?

HGH Fragment 176-191 is generally not appropriate for: Pregnancy; Banned in drug-tested sport. Talk to a licensed clinician before starting.

New?New to peptides?Start here →

Decoding

HGH Fragment 176-191_

Q: What is HGH Fragment 176-191?

HGH Fragment 176-191 is a hgh fragment used for fat loss. HGH Fragment 176-191 is the tail end of the growth hormone molecule, the part linked to fat breakdown. In plain terms: it aims to target stubborn fat without the rest of growth hormone's effects, but real human evidence is thin.

Q: Do you cycle HGH Fragment 176-191?

Studied as daily dosing for up to 12 weeks The same molecule as AOD-9604, given daily for up to 12 weeks in the obesity trials with no cycling and no benefit over placebo.

Also known as HGH Frag, Frag 176-191, Fragment 176-191

The fat-burning piece of growth hormone, aimed at stubborn fat.

Fat lossHGH fragmentResearch only

Common vial size5 mg

Dose0.25 up to 0.5 mg per day (start low, increase slowly)

FrequencyDaily

RouteUnder the skin (subcutaneous)

StatusResearch only

MixYour choice, calculate it

CycledStudied as daily dosing for up to 12 weeks

Common vial size is what vendors typically sell, not a recommendation. Enter your own vial in the calculator.

What is HGH Fragment 176-191?

Plain language first. The technical label stays, but it never stands alone.

Overview

HGH Fragment 176-191 is the tail end of the growth hormone molecule, the part linked to fat breakdown. In plain terms: it aims to target stubborn fat without the rest of growth hormone's effects, but real human evidence is thin.

What it's used for

People use it to try to target stubborn fat. Real human evidence is thin.

How does HGH Fragment 176-191 work?

What it does in the body, and where.

The fragment is the last section of the growth hormone molecule, residues 176 to 191, isolated because that region is associated with fat breakdown.

01
It copies the fat-releasing region only
Signalling fat cells to release stored fat, without the rest of the growth hormone molecule.
02
It does not raise IGF-1
So the muscle-growth and blood-sugar effects of full growth hormone do not follow.
03
The human evidence is thin
Animal results were encouraging. Trials in people, including on its close relative AOD-9604, did not reproduce them.

Pathway

A schematic of the compound's mechanism, not a diagnostic image.

What else is it used for?

Each use below carries its own evidence level. Approved means regulators have cleared it for that purpose. Investigational means it is in trials. Early research means it is being studied and is not established.

Targeting stubborn fat without growth hormone's other effectsResearch only
Fat loss without raising IGF-1, which is the claimed advantage over growth hormone itselfEarly research

How much, and do you cycle it?

The range, and whether you take breaks.

0.25 up to 0.5 mg per day (start low, increase slowly), daily. Studied as daily dosing for up to 12 weeksTrial dose

The same molecule as AOD-9604, given daily for up to 12 weeks in the obesity trials with no cycling and no benefit over placebo.

Compare cycling across compounds →

How do I dose and price it?

Enter your vial and your dose. Pick a mix. We show the draw and the cost.

The vial holds a fixed amount of drug. Adding more water does not make more drug, it just spreads it thinner, so you draw a bigger number on the syringe for the same dose.

Your vial size (mg)

Printed on the vial.

What you paid per vial

Used for cost per dose only.

Your dose (mcg)

Commonly referenced range: 0.25 up to 0.5 mg per day (start low, increase slowly)Community practice

Choose your mix

0.5 mL water2.5units · 10 mg/mL

Half a 100-unit syringe

1 mL water5units · 5 mg/mL

One full 100-unit syringe

Easiest

2 mL water10units · 2.5 mg/mL

Two full 100-unit syringes

your own mL

units · —

Enter your own volume

Measuring the water1 mL = one full 100-unit syringe.

Your draw

10 / 100 units

Full calculator with reorder date →Read a syringe →

How do you store it?

Before mixing, and after.

Dry powder in the freezer or fridge. Once mixed, fridge, and use within about a month.

Unmixed lyophilized HGH Fragment 176-191 keeps for a long time cold. Once you add water the clock starts: most reconstituted vials hold up for roughly 28 to 30 days at fridge temperature. Keep it out of light, and do not freeze it after mixing.

What are the side effects and cautions?

Known cautions and warnings for this compound.

Who should avoid it

Check these before anything else.

Pregnancy
Banned in drug-tested sport

Stop and get help

These are emergencies. Seek care.

Signs of an allergic reaction

Common effects

Expected, and usually mild.

Safety is inferred from the related compound AOD-9604, which was well tolerated and did not raise IGF-1
This bare fragment has no independent trial database of its own

Where this page says nothing is established, that means nobody has studied it, not that a compound is safe.

Is HGH Fragment 176-191 approved?

And where the numbers on this page come from.

Research only

No. Not FDA-approved.

Sold for research use only. Not cleared for human consumption or medical use.

DoseFrom research and community reports. No regulator has reviewed this dose.
Vial sizeFrom what vendors typically list; not a recommendation.
Reviewed22 July 2026

What else is like HGH Fragment 176-191?

Others in Weight loss and metabolic, side by side.

If you're weighing HGH Fragment 176-191, it's worth reading Semaglutide, Tirzepatide, and Retatrutide in the same class.

YOU ARE HERE

HGH Fragment 176-191

The fat-burning piece of growth hormone, aimed at stubborn fat.

Research only

Dose: 0.25 up to 0.5 mg per day (start low, increase slowly)
How often: Daily

Semaglutide

The drug in Ozempic and Wegovy: a weekly shot that curbs hunger for steady weight loss.

FDA-approved

Dose: 0.25 up to 2.4 mg per week (start low, increase slowly)
How often: Weekly

Tirzepatide

The drug in Mounjaro and Zepbound: a weekly shot for major weight loss and blood sugar.

FDA-approved

Dose: 2.5 up to 15 mg per week (start low, increase slowly)
How often: Weekly

Retatrutide

An experimental weekly shot with some of the biggest weight-loss numbers yet in trials.

Investigational

Dose: 1 up to 12 mg per dose (start low, increase slowly)
How often: Weekly

What these words mean

Show glossary +

Titrate: Starting at a low dose and increasing it slowly over time so your body adjusts and side effects stay mild.
Subcutaneous: An injection just under the skin, into the fat layer, usually with a short, thin insulin needle.
Intramuscular (IM): An injection into a muscle, using a longer needle.
Reconstitution: Mixing a powdered peptide with liquid (bacteriostatic water) so it can be drawn into a syringe.
Bacteriostatic water: Sterile water with a tiny amount of preservative, used to mix powdered peptides.
Concentration: How strong the mixed peptide is, in milligrams per milliliter (mg/mL). More water makes it weaker; less water makes it stronger.
Units (on the syringe): The marks on an insulin syringe. 100 units equals 1 mL. They measure how much liquid you draw, not the dose in milligrams.
mcg and mg: Units of dose. 1 milligram (mg) equals 1,000 micrograms (mcg).
GLP-1: A natural gut hormone that lowers appetite and blood sugar. Drugs that copy it, like semaglutide, are used for weight loss.
Growth hormone secretagogue: A compound that nudges your body to release more of its own growth hormone, rather than injecting the hormone itself.
Half-life: How long a compound stays active in your body. A longer half-life means you inject less often.
Peptide vs small molecule: A peptide is a short chain of amino acids. A few items here (like MK-677 or methylene blue) are small molecules, not true peptides, but people use them the same way.
Research only: No approved dose or use in people. Sold for research and not reviewed by the FDA for safety or quality.
Investigational: Still being tested in clinical trials and not yet approved or legally sold for general use.
Banned in drug-tested sport: Prohibited by the World Anti-Doping Agency (WADA); using it can disqualify a competing athlete.

Last reviewed 22 July 2026