HGH Fragment 176-191_Dosage, benefits & legal status
Also known as HGH Frag, Frag 176-191, Fragment 176-191
The fat-burning piece of growth hormone, aimed at stubborn fat.
Common vial size is what vendors typically sell, not a recommendation. Enter your own vial in the calculator.
What is HGH Fragment 176-191?
Plain language first. The technical label stays, but it never stands alone.Overview
It aims to target stubborn fat without the rest of growth hormone's effects, but real human evidence is thin.
HGH Fragment 176-191 is the tail end of the growth hormone molecule, the part linked to fat breakdown.
What it's used for
People use it to try to target stubborn fat. Real human evidence is thin.
How does HGH Fragment 176-191 work?
What it does in the body, and where.The fragment is the last section of the growth hormone molecule, residues 176 to 191, isolated because that region is associated with fat breakdown.
- 01It copies the fat-releasing region onlySignalling fat cells to release stored fat, without the rest of the growth hormone molecule.
- 02It does not raise IGF-1So the muscle-growth and blood-sugar effects of full growth hormone do not follow.
- 03The human evidence is thinAnimal results were encouraging. Trials in people, including on its close relative AOD-9604, did not reproduce them.
A schematic of the compound's mechanism, not a diagnostic image.
What else is it used for?
Each use below carries its own evidence level. Approved means regulators have cleared it for that purpose. Investigational means it is in trials. Early research means it is being studied and is not established.
- Targeting stubborn fat without growth hormone's other effectsResearch only
- Fat loss without raising IGF-1, which is the claimed advantage over growth hormone itselfEarly research
The published record
2
Records indexed for HGH Fragment 176-191
2 in humans, 1 of them original studies.
Counted from Europe PMC indexing, not read by a person. Human means indexed under humans, which includes reviews and work on human cells. Original studies exclude reviews and lab work on human cells.Last updated 11 September 2026.
At a glance
Four things to know about HGH Fragment 176-191
Evidence
Research only
Category
Weight loss and metabolic
Common vial
5 mg
Half-life
Not established
How much, and do you cycle it?
The range, and whether you take breaks.0.25 up to 0.5 mg per day (start low, increase slowly), daily. Studied as daily dosing for up to 12 weeksTrial dose
The same molecule as AOD-9604, given daily for up to 12 weeks in the obesity trials with no cycling and no benefit over placebo.
How long does it stay in the body?
The half-life, and where the figure comes from.Not establishedCommunity practice
Never studied in humans. The 15 to 30 minutes quoted online is borrowed from AOD-9604, which is a related but different fragment.
Not yet traced to a primary source.
You can compare this against the whole library to see where it sits.
How do I dose and price it?
Enter your vial and your dose. Pick a mix. We show the draw and the cost.The vial holds a fixed amount of drug. Adding more water does not make more drug, it just spreads it thinner, so you draw a bigger number on the syringe for the same dose.
Choose your mix
Measuring the water1 mL = one full 100-unit syringe.
Your draw
10 / 100 unitsHGH Fragment 176-191 starts at $27.99 across 15 vendors, typically $5.60 – $17.00 per mg.
25 listings, last read Sep 5, 2026. Shipping and card fees are not included.
How do you store it?
Before mixing, and after.Dry powder in the freezer or fridge. Once mixed, fridge, and use within about a month.
Unmixed lyophilized HGH Fragment 176-191 keeps for a long time cold. Once you add water the clock starts: most reconstituted vials hold up for roughly 28 to 30 days at fridge temperature. Keep it out of light, and do not freeze it after mixing.
What are the side effects and cautions?
Known cautions and warnings for this compound.Who should avoid it
- Pregnancy
- Banned in drug-tested sport
Stop and get help
- Signs of an allergic reaction
Common effects
- Safety is inferred from the related compound AOD-9604, which was well tolerated and did not raise IGF-1
- This bare fragment has no independent trial database of its own
Where this page says nothing is established, that means nobody has studied it, not that a compound is safe.
Is HGH Fragment 176-191 approved?
And where the numbers on this page come from.No. HGH Fragment 176-191 is not approved for any use, anywhere. It is sold labelled for laboratory research only, and there is no legal route to buy it for human use.
- Approval statusResearch only
- RouteUnder the skin (subcutaneous)
- CheckedJuly 2026
What has happened recently
We have not yet written a full regulatory note for this compound. The status above is current as of the date shown.
Banned in drug-tested sport. Most research peptides are prohibited under WADA's S0 category, which covers any substance with no approval from any regulatory authority for human use. That means a compound can be banned without ever being named on the prohibited list. Check with your own anti-doping authority rather than assuming absence from the list means permitted.
You can compare this against the whole library, or read how to check a seller.
- DoseFrom research and community reports. No regulator has reviewed this dose.
- Vial sizeFrom what vendors typically list; not a recommendation.
- Sources
- Reviewed22 July 2026
What else is like HGH Fragment 176-191?
Others in Fat loss without GLP-1, side by side.If you're weighing HGH Fragment 176-191, it's worth reading 5-Amino-1MQ, SLU-PP-332, and Setmelanotide (Imcivree) in the same class.
The fat-burning piece of growth hormone, aimed at stubborn fat.
- Dose
- 0.25 up to 0.5 mg per day (start low, increase slowly)
- How often
- Daily
A capsule studied for speeding up metabolism and burning fat.
- Dose
- 0.15 up to 5 mg per day injected (the capsule dose is far higher, see below)
- How often
- Daily, cycled
An experimental 'exercise in a molecule,' very early and unproven in people.
- Dose
- Research only
- How often
- Cycled
An approved daily shot for rare genetic forms of obesity.
- Dose
- 2 up to 3 mg per day (start low, increase slowly)
- How often
- Daily
Guides for this compound
- How to Reconstitute a Peptide
Mix peptide powder with bacteriostatic water, step by step.
- How to Read an Insulin Syringe
Read the units, convert to millilitres, and draw the exact dose.
- mcg vs mg: The Peptide Dosing Mistake to Avoid
Your vial says mg and your protocol says mcg. Here is the conversion and how to check it.
- How to Read a Peptide COA
What the purity number does and does not tell you, and how to spot an edited report.
- How to Vet a Peptide Vendor
Independent COAs, HPLC purity, and the red flags that mean walk away.
Sources
- FDA, bulk drug substances nominated for use in compounding under section 503A, updated 14 May 2026(2026)Somatropin, full-length human growth hormone, is an approved drug with a prescribing label. This fragment of it appears in none of the three categories on FDA's nomination list. Being a piece of an approved molecule confers nothing: the fragment is a different substance and has never been proposed for compounding. This list is the comprehensive record of what has been proposed for pharmacy compounding since the process opened in 2013, when over two thousand substances were nominated, so absence from all three categories means no one has ever put this compound forward.
Last reviewed 22 July 2026
Beyond these, 2 records are indexed. Browse the records