Amyloid Beta_Dosage, benefits & legal status
Also known as beta-amyloid, amyloid beta peptide, A4 amyloid
The peptide that builds Alzheimer's plaques, sold as a lab reagent.
Common vial size is what vendors typically sell, not a recommendation. Enter your own vial in the calculator.
What is Amyloid Beta?
Plain language first. The technical label stays, but it never stands alone.Overview
The sticky peptide that clumps into Alzheimer's plaques. Labs use it to cause that damage on purpose, and it is not a treatment for anything.
Amyloid beta (Aβ) comprises peptides of roughly 39 to 43 residues cleaved from amyloid precursor protein, chiefly Aβ1-40 and the more aggregation-prone Aβ1-42. "A4" is an early name for the plaque-core peptide. The listing tracked here does not state which length it supplies. Synthetic Aβ is used as a reagent to generate oligomers, fibrils and plaque pathology in experimental models.
What it's used for
A laboratory reagent for modelling Alzheimer's disease. It has no use as a supplement or treatment.
How does Amyloid Beta work?
What it does in the body, and where.Amyloid beta is a normal product of the brain that becomes harmful when it clumps together.
- 01It is cut from a larger proteinEnzymes trim amyloid precursor protein, found on nerve cells, into short fragments. Amyloid beta is one of them.
- 02It sticks to itselfSingle copies pair up, then form small clusters and long fibres. The fibres collect into the plaques seen in Alzheimer's brains.
- 03Clusters can seed more clumpingAggregated amyloid beta can make fresh copies misfold, which is why contaminated growth hormone given decades ago appears to have passed the pathology on.
- 04That is why labs buy itAdding it to cells or animals produces Alzheimer's-like damage on demand, so drug candidates can be tested against it.
What else is it used for?
Each group carries its own evidence level.Approved means regulators have cleared it for that purpose. Investigational means it is in trials. Early research means it is being studied and is not established.
Injected into people
Investigational- Human trialIn the AN1792 trial, people with Alzheimer's received aggregated amyloid beta 1-42 with an immune-boosting adjuvant. Dosing stopped after 18 of 298 treated patients (6%) developed brain inflammation.
- Human trialOnly 59 of 300 patients produced the intended antibody response, and standard memory and function scores did not differ from placebo at 12 months.
Transmission
Research only- Human observationPeople treated as children with growth hormone taken from cadaver pituitary glands, some batches of which carried amyloid beta, went on to develop early-onset Alzheimer's disease decades later. The authors describe it as the first evidence of medically acquired Alzheimer's in living people.
Because it appears on peptide sites beside injectable products, amyloid beta can look like something people take. It is the peptide that builds Alzheimer's plaques. In people, a vaccine made from it caused brain inflammation, and contaminated growth hormone carrying it appears to have transmitted Alzheimer's pathology decades later.
The published record
Papers and trials about Amyloid Beta
90 papers tagged human · 54 not reviews or lab · 10 clinical trial publications
1 registered trials · none with posted results
Counted from Europe PMC indexing, not read by a person; a human tag can land on reviews, commentary or lab papers; clinical trial publications is the narrower count.
At a glance
Four things to know about Amyloid Beta
Evidence
Research only
Category
Brain, mood and sleep
Common vial
Varies
Half-life
Not applicable
How much, and do you cycle it?
The range, and whether you take breaks.No dose: a lab reagent, not applicable. Not applicableNo range
It is not taken for any purpose, so no schedule exists.
How long does it stay in the body?
The half-life, and where the figure comes from.Not applicableNo figure
Not a treatment, so no dosing half-life applies.
You can compare this against the whole library to see where it sits.
What does it cost?
Typical dose and cost, in plain numbers.Amyloid Beta is not injected
It is taken not taken as a treatment. Amyloid beta is not taken as a treatment. The only dosing in people on record is the AN1792 vaccine trial, which used an adjuvanted injection of the aggregated peptide and was stopped for brain inflammation.
Amyloid Beta starts at $34.59 across 1 vendor.
1 listing, last read Sep 27, 2026. Shipping and card fees are not included.
How do you store it?
Before mixing, and after.Dry powder in the freezer or fridge. Once mixed, fridge, and use within about a month.
Unmixed lyophilized Amyloid Beta keeps for a long time cold. Once you add water the clock starts: most reconstituted vials hold up for roughly 28 to 30 days at fridge temperature. Keep it out of light, and do not freeze it after mixing.
What are the side effects and cautions?
Known cautions and warnings for this compound.Who should avoid it
- Any personal use: it is a reagent for creating disease in experimental models
Stop and get help
- Headache, confusion, fever or drowsiness after any exposure, which were the signs of brain inflammation in the vaccine trial
Common effects
- Not applicable: it is not taken for any effect
Where this page says nothing is established, that means nobody has studied it, not that a compound is safe.
Is Amyloid Beta approved?
And where the numbers on this page come from.No. Amyloid Beta is not approved for any use, anywhere. It is sold labelled for laboratory research only, and there is no legal route to buy it for human use.
- Approval statusResearch only
- RouteNot taken as a treatment
- Checked29 September 2026
- DoseFrom research and community reports. No regulator has reviewed this dose.
- Vial sizeFrom what vendors typically list; not a recommendation.
- SourcesOrgogozo JM, et al. Subacute meningoencephalitis in a subset of patients with AD after Aβ42 immunization. NeurologyGilman S, et al. Clinical effects of Aβ immunization (AN1792) in patients with AD in an interrupted trial. NeurologyBanerjee G, et al. Iatrogenic Alzheimer's disease in recipients of cadaveric pituitary-derived growth hormone. Nature Medicine
What has happened recently
Not approved for any use in people. Sold as a laboratory reagent.
You can compare this against the whole library, or read how to check a seller.
What else is like Amyloid Beta?
Others in Brain, mood and sleep, side by side.If you're weighing Amyloid Beta, it's worth reading Semax, Selank, and N-Acetyl Semax Amidate in the same class.
The peptide that builds Alzheimer's plaques, sold as a lab reagent.
- Dose
- No dose: a lab reagent
- How often
- Not applicable
A peptide used for sharper focus, memory, and mental clarity.
- Dose
- 0.2 up to 0.6 mg per day
- How often
- 1-2x daily
A peptide that eases anxiety while keeping you clear-headed.
- Dose
- 0.25 up to 0.5 mg per day
- How often
- 1-2x daily
A longer-lasting version of Semax for focus and memory.
- Dose
- 0.2 up to 0.4 mg per day
- How often
- 1-2x daily
Guides for this compound
- How to Reconstitute a Peptide
Mix peptide powder with bacteriostatic water, step by step.
- How to Read an Insulin Syringe
Read the units, convert to millilitres, and draw the exact dose.
- mcg vs mg: The Peptide Dosing Mistake to Avoid
Your vial says mg and your protocol says mcg. Here is the conversion and how to check it.
- How to Read a Peptide COA
What the purity number does and does not tell you, and how to spot an edited report.
- How to Vet a Peptide Vendor
Independent COAs, HPLC purity, and the red flags that mean walk away.
Sources
- Orgogozo JM, et al. Subacute meningoencephalitis in a subset of patients with AD after Aβ42 immunization. Neurology(2003)Brain inflammation in 18 of 298 patients given aggregated Aβ42 with adjuvant; dosing stopped.
- Gilman S, et al. Clinical effects of Aβ immunization (AN1792) in patients with AD in an interrupted trial. Neurology(2005)59 of 300 patients produced the target antibody response; no difference from placebo on standard cognitive and functional scales.
- Banerjee G, et al. Iatrogenic Alzheimer's disease in recipients of cadaveric pituitary-derived growth hormone. Nature Medicine(2024)Early-onset Alzheimer's in people given cadaver-derived growth hormone in childhood, attributed to amyloid-beta transmission.
Last reviewed 29 September 2026
Beyond these, 137 records are indexed. Browse the records