Splenopentin_Dosage, benefits & legal status
Also known as SP-5, splenopentin acetate, DAC:SP-5
A five-amino-acid spleen peptide, sold on an evidence base almost nobody has read.
Common vial size is what vendors typically sell, not a recommendation. Enter your own vial in the calculator.
What is Splenopentin?
Plain language first. The technical label stays, but it never stands alone.Overview
A five-amino-acid spleen fragment sold for immune support. The research is decades old and almost nobody has repeated it.
Splenopentin, a pentapeptide fragment of splenin, investigated as an immunomodulator alongside thymopentin in the tissue-fragment peptide era. No modern controlled human trial has been published and no dose is established.
What it's used for
An immune peptide sold for immune support and bone marrow recovery.
How does Splenopentin work?
What it does in the body, and where.Splenopentin belongs to the same era and idea as thymopentin, and shares its problem.
- 01It is a fragment of a larger spleen proteinSplenopentin is described as the active five-residue region of splenin, in the same way thymopentin is the active fragment of thymopoietin.
- 02The claimed action is on immune cell maturationReported to influence the development of immune cells and to support blood cell recovery after marrow damage.
- 03The literature is old and largely unrepeatedThe work dates from the era when tissue-fragment peptides were an active field. Little independent modern research exists, and nothing establishes a dose.
What else is it used for?
Each use below carries its own evidence level. Approved means regulators have cleared it for that purpose. Investigational means it is in trials. Early research means it is being studied and is not established.
- Immune cell maturationEarly research
- Bone marrow recovery after chemotherapy or radiationEarly research
- Immune support generallyResearch only
The published record
Papers and trials about Splenopentin
18 papers tagged human · 11 not reviews or lab · 3 clinical trial publications
Furthest stage reached: Published trials only, 3 clinical trial publications, no phased trial registered
Counted from Europe PMC indexing, not read by a person; a human tag can land on reviews, commentary or lab papers; clinical trial publications is the narrower count.
At a glance
Four things to know about Splenopentin
How much, and do you cycle it?
The range, and whether you take breaks.Research only, not established. Not established No range
No schedule has been studied for this compound in people.
Nothing publishedNo figure
No half-life for splenopentin has been located in published sources.
You can compare this against the whole library to see where it sits.
How do I dose and price it?
Enter your vial and your dose. Pick a mix. We show the draw and the cost.The vial holds a fixed amount of drug. Adding more water does not make more drug, it just spreads it thinner, so you draw a bigger number on the syringe for the same dose.
Choose your mix
Measuring the water1 mL = one full 100-unit syringe.
How do you store it?
Before mixing, and after.Dry powder in the freezer or fridge. Once mixed, fridge, and use within about a month.
Unmixed lyophilized Splenopentin keeps for a long time cold. Once you add water the clock starts: most reconstituted vials hold up for roughly 28 to 30 days at fridge temperature. Keep it out of light, and do not freeze it after mixing.
What are the side effects and cautions?
Known cautions and warnings for this compound.Solubility, computed: 100% charged residues, 20% hydrophobic. Water usually sufficient.
A first-pass rule from peptide manufacturers' guidance. It does not account for disulfide bridges, salt form or how the powder was dried, and it predicts what should be easy rather than what will happen in your vial.
Who should avoid it
- Pregnancy or breastfeeding
- An autoimmune condition, without medical advice
- Cancer treatment, where an unstudied peptide is not a substitute for supportive care that has been tested
- Anyone who wants established safety data, because none exists for this compound in humans
Stop and get help
- Signs of an allergic reaction, including spreading hives, facial or throat swelling, or trouble breathing
- Redness, heat, or pus at the injection site, which can signal infection
- Anything unusual, since there is no known safety profile to compare it against
Common effects
- Unknown. No study has recorded what this commonly causes in people
- Redness, soreness, or a small bump at the injection site
Where this page says nothing is established, that means nobody has studied it, not that a compound is safe.
Is Splenopentin approved?
And where the numbers on this page come from.No. Splenopentin is not approved for any use, anywhere. It is sold labeled for laboratory research only, and there is no legal route to buy it for human use.
- Approval statusResearch only
- RouteUnder the skin (subcutaneous)
- Checked24 August 2026
- DoseFrom community reports. No regulator or trial established this dose.
- Vial sizeFrom what vendors typically list; not a recommendation.
- SourcesNone traced yet.
What has happened recently
We have not yet written a full regulatory note for this compound. The status above is current as of the date shown.
You can compare this against the whole library, or read how to check a seller.
What else is like Splenopentin?
Others in Immune support, side by side.If you're weighing Splenopentin, it's worth reading Thymopentin (TP-5), Tuftsin, and Thymosin Alpha-1 in the same class.
A five-amino-acid spleen peptide, sold on an evidence base almost nobody has read.
- Dose
- Research only
- How often
- Not established
Five amino acids that carry the whole activity of a thymus hormone.
- Dose
- 50 mg per dose
- How often
- 3x per week
A four-amino-acid immune peptide from the 1970s, and the parent of Selank.
- Dose
- Research only
- How often
- Not established
A well-studied shot that tunes up the immune system.
- Dose
- 1.6 mg per dose
- How often
- 2x per week
Guides for this compound
- How to Reconstitute a Peptide
Mix peptide powder with bacteriostatic water, step by step.
- How to Read an Insulin Syringe
Read the units, convert to millilitres, and draw the exact dose.
- mcg vs mg: The Peptide Dosing Mistake to Avoid
Your vial says mg and your protocol says mcg. Here is the conversion and how to check it.
- How to Read a Peptide COA
What the purity number does and does not tell you, and how to spot an edited report.
- How to Vet a Peptide Vendor
Independent COAs, HPLC purity, and the red flags that mean walk away.
Sources
No primary source has been traced for this compound yet. Treat everything on this page as unverified until one is. How we grade evidence
Beyond these, 41 records are indexed. Browse the records