Sermorelin + GHRP-2 blend_Dosage, benefits & legal status
Also known as Sermorelin + GHRP-2, Sermorelin/GHRP-2, Serm GHRP2 blend
A growth hormone pairing in one vial, where the sermorelin dose sets the GHRP-2 dose whether you want it to or not.
Common vial size is what vendors typically sell, not a recommendation. Enter your own vial in the calculator.
What is Sermorelin + GHRP-2 blend?
Plain language first. The technical label stays, but it never stands alone.Overview
It combines two peptides that each nudge the pituitary to release growth hormone, through two different receptors, in a single injection. Sermorelin is the same signal fragment the body uses; GHRP-2 adds a second, stronger push that also brings hunger.
What it's used for
Raising growth hormone release for body composition, recovery, and sleep, with one injection instead of two.
How does Sermorelin + GHRP-2 blend work?
What it does in the body, and where.Sermorelin + GHRP-2 pairs two growth hormone secretagogues that work through different receptors. The blend itself has never been tested.
- 01
- 02GHRP-2 acts on the ghrelin receptorIt binds a separate receptor on the pituitary and hypothalamus. That also triggers growth hormone release, and it is why hunger often rises.
- 03The pairing is an assumption, not a findingThe argument for the blend is that two receptors are better than one. Nobody has tested this vial against either peptide alone.
A schematic of the compound's mechanism, not a diagnostic image.
What else is it used for?
Each use below carries its own evidence level. Approved means regulators have cleared it for that purpose. Investigational means it is in trials. Early research means it is being studied and is not established.
- Raising growth hormone release through two receptors at onceResearch only
- Convenience, since it puts two peptides into one injectionResearch only
At a glance
Four things to know about Sermorelin + GHRP-2 blend
Evidence
Category
Growth hormone
Common vial
10 mg
Half-life
GHRP-2 about 33 minutes; no usable figure for sermorelin here
How much, and do you cycle it?
The range, and whether you take breaks.0.2 up to 0.5 mg sermorelin per dose (the GHRP-2 follows your ratio), daily, often at night. Each half is cycled on its own schedule, usually 8 to 12 weeks on and 4 off Community practice
Continuous exposure to a ghrelin-receptor peptide such as GHRP-2 blunts the growth hormone response to a later dose. That is documented in people. The on and off schedule is not: no study has tested this blend on any schedule.
Source: 24-hour GHRP infusion attenuates the response to a later GHRP bolus (J Clin Endocrinol Metab, 1993)
GHRP-2 about 33 minutes; no usable figure for sermorelin hereHuman study
The GHRP-2 figure was measured in children, given into a vein. The blend cannot have a single number when only one half has one.
Source: Pihoker C, et al. J Clin Endocrinol Metab 1998;83(4):1168-72, PMID 9543135 (GHRP-2 only)
You can compare this against the whole library to see where it sits.
How do I dose and price it?
Enter your vial and your dose. Pick a mix. We show the draw and the cost.The vial holds a fixed amount of drug. Adding more water does not make more drug, it just spreads it thinner, so you draw a bigger number on the syringe for the same dose.
The only ratio printed on the vendor pages checked was 2 mg of each. Some sellers list a 10 mg vial without stating the split, and a vial whose label does not give the amount of each peptide cannot be dosed. Pick the option that matches your label, or enter your own.
Pick your vial to see concentrations and a draw.
Choose your mix
Measuring the water1 mL = one full 100-unit syringe.
Your draw
What one draw delivers
The same arithmetic as the calculator, worked out for the vials vendors sell.Dose anchored to Sermorelin, at the 0.2 to 0.5 mg per dose people commonly cite. Each table assumes one draw per dose. If you split it across more injections, divide the reading by the number of injections.
| Sermorelin dose | 1 mL water | 2 mL water | 3 mL water |
|---|---|---|---|
| 0.2 mg | 10.0 units
| 20.0 units
| 30.0 units
|
| 0.5 mg | 25.0 units
| 50.0 units
| 75.0 units
|
No published human study establishes a dose for this blend. The range is anchored to sermorelin, because a blend is one draw.
Sermorelin is usually cited at 200 to 500 mcg and GHRP-2 at 100 to 300 mcg. One draw from a 1:1 vial at the top of the sermorelin range delivers 500 mcg of GHRP-2, above its own range. The fixed ratio means you cannot raise one without raising the other.
Sermorelin + GHRP-2 blend starts at $43.25 across 5 vendors, typically $8.80 – $21.63 per mg.
9 listings, last read Oct 24, 2026. Shipping and card fees are not included.
How do you store it?
Before mixing, and after.Dry powder in the freezer or fridge. Once mixed, fridge, and use within about a month.
Unmixed lyophilized Sermorelin + GHRP-2 blend keeps for a long time cold. Once you add water the clock starts: most reconstituted vials hold up for roughly 28 to 30 days at fridge temperature. Keep it out of light, and do not freeze it after mixing.
What are the side effects and cautions?
Known cautions and warnings for this compound.Some sellers list this blend as a 10 mg vial without printing how much of each peptide it holds. If your label does not give the amount of each, the dose cannot be worked out. Ask the vendor or do not use the vial.
Who should avoid it
- Active cancer, as a precaution with anything raising growth hormone
- Pregnancy
- Banned in drug-tested sport
Stop and get help
- Signs of an allergic reaction
- Persistent milky nipple discharge, a sign of raised prolactin from the GHRP-2
Common effects
- Injection-site reactions
- Increased hunger, from the GHRP-2
- Water retention
- Tiredness after dosing
- Flushing or warmth after injection
- This is a blend, so the cautions of both peptides apply at once. It is also harder to tell which one caused a reaction.
Where this page says nothing is established, that means nobody has studied it, not that a compound is safe.
Is Sermorelin + GHRP-2 blend approved?
And where the numbers on this page come from.No. Sermorelin + GHRP-2 blend is not approved for any use, anywhere. It is sold labeled for laboratory research only, and there is no legal route to buy it for human use.
- Approval statusResearch only
- RouteUnder the skin (subcutaneous)
- Checked31 October 2026
- DoseFrom community reports. No regulator or trial established this dose.
- Vial sizeFrom what vendors typically list; not a recommendation.
- SourcesNone traced yet.
What has happened recently
We have not yet written a full regulatory note for this compound. The status above is current as of the date shown.
Banned in drug-tested sport. Most research peptides are prohibited under WADA's S0 category, which covers any substance with no approval from any regulatory authority for human use. That means a compound can be banned without ever being named on the prohibited list. Check with your own anti-doping authority rather than assuming absence from the list means permitted.
You can compare this against the whole library, or read how to check a seller.
What else is like Sermorelin + GHRP-2 blend?
Others in Growth hormone peptides, side by side.If you're weighing Sermorelin + GHRP-2 blend, it's worth reading Sermorelin + GHRP-6 blend, Somapacitan (Sogroya), and Somatostatin in the same class.
A growth hormone pairing in one vial, where the sermorelin dose sets the GHRP-2 dose whether you want it to or not.
- Dose
- 0.2 up to 0.5 mg sermorelin per dose (the GHRP-2 follows your ratio)
- How often
- Daily, often at night
A growth hormone pairing in one vial, with the strongest appetite push of the GHRP family built in.
- Dose
- 0.2 up to 0.5 mg sermorelin per dose (the GHRP-6 follows your ratio)
- How often
- Daily, often at night
Weekly because albumin holds onto it, not because it lasts a week.
- Dose
- 0.16 to 0.24 mg/kg weekly
- How often
- Once weekly
A hormone that works, with a half-life too short to be practical.
- Dose
- 3.5 mcg/kg/hour
- How often
- Continuous infusion, 48 to 120 hours
Guides for this compound
- How to Reconstitute a Peptide
Mix peptide powder with bacteriostatic water, step by step.
- How to Read an Insulin Syringe
Read the units, convert to millilitres, and draw the exact dose.
- mcg vs mg: The Peptide Dosing Mistake to Avoid
Your vial says mg and your protocol says mcg. Here is the conversion and how to check it.
- Why Does My Peptide Injection Itch or Welt
Injection-site irritation, a histamine reaction, or a true allergy, and how to tell them apart.
- How to Read a Peptide COA
What the purity number does and does not tell you, and how to spot an edited report.
Sources
No primary source has been traced for this compound yet. Treat everything on this page as unverified until one is. How we grade evidence