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Sermorelin + GHRP-6 blend_Dosage, benefits & legal status

Also known as Sermorelin + GHRP-6, Sermorelin/GHRP-6, Serm GHRP6 blend

Published October 31, 2026

A growth hormone pairing in one vial, with the strongest appetite push of the GHRP family built in.

Recovery & muscleGHRH + GHRP comboResearch only
Common vial size4 mg
Dose0.2 up to 0.5 mg sermorelin per dose (the GHRP-6 follows your ratio)
FrequencyDaily, often at night
RouteUnder the skin (subcutaneous)
StatusResearch only
CycledEach half is cycled on its own schedule, usually 8 to 12 weeks on and 4 off

Common vial size is what vendors typically sell, not a recommendation. Enter your own vial in the calculator.

See how this dose compares across the library →

01

What is Sermorelin + GHRP-6 blend?

Plain language first. The technical label stays, but it never stands alone.

Overview

It combines two peptides that each nudge the pituitary to release growth hormone, through two different receptors, in a single injection. GHRP-6 is the strongest appetite stimulant of its family, so this pairing is the one most associated with hunger.

The technical version

Sermorelin + GHRP-6 is a pre-mixed blend of a GHRH analog and a ghrelin-receptor peptide.

What it's used for

Raising growth hormone release for body composition, recovery, and appetite, with one injection instead of two.

02

How does Sermorelin + GHRP-6 blend work?

What it does in the body, and where.

Sermorelin + GHRP-6 pairs two growth hormone secretagogues that work through different receptors. The blend itself has never been tested.

  1. 01
    Sermorelin acts like the body's own GHRH
    It is a fragment of growth hormone-releasing hormone and binds the GHRH receptor on the pituitary, the same signal the hypothalamus uses.
  2. 02
    GHRP-6 acts on the ghrelin receptor
    It binds a separate receptor on the pituitary and hypothalamus. That also triggers growth hormone release, and GHRP-6 is the strongest appetite stimulant of its family.
  3. 03
    The pairing is an assumption, not a finding
    The argument for the blend is that two receptors are better than one. Nobody has tested this vial against either peptide alone.
Pathway
THE PEPTIDE
Sermorelin + GHRP-6 blend
ACTS ON
Two growth hormone signals at once
RESULT
A GHRH push plus a strong GHRP-6 pulse

A schematic of the compound's mechanism, not a diagnostic image.

03

What else is it used for?

Each use below carries its own evidence level. Approved means regulators have cleared it for that purpose. Investigational means it is in trials. Early research means it is being studied and is not established.

  • Raising growth hormone release through two receptors at onceResearch only
  • Convenience, since it puts two peptides into one injectionResearch only
Sermorelin + GHRP-6 blend vial rendering
Compound field notes

At a glance

Four things to know about Sermorelin + GHRP-6 blend

01

Evidence

Research only

02

Category

Growth hormone

03

Common vial

4 mg

04

Half-life

No usable human figure for either half

04

How much, and do you cycle it?

The range, and whether you take breaks.

0.2 up to 0.5 mg sermorelin per dose (the GHRP-6 follows your ratio), daily, often at night. Each half is cycled on its own schedule, usually 8 to 12 weeks on and 4 off Community practice

Continuous exposure to a ghrelin-receptor peptide such as GHRP-6 blunts the growth hormone response to a later dose. That is documented in people for its family. The on and off schedule is not: no study has tested this blend on any schedule.

Source: 24-hour GHRP infusion attenuates the response to a later GHRP bolus (J Clin Endocrinol Metab, 1993)

Compare this against the whole library →

05

How long does it stay in the body?

The half-life, and where the figure comes from.

No usable human figure for either halfNo figure

Neither peptide has a published human half-life measurement that traces to a primary source. The blend cannot have a single number when neither half has one.

You can compare this against the whole library to see where it sits.

06

How do I dose and price it?

Enter your vial and your dose. Pick a mix. We show the draw and the cost.

The vial holds a fixed amount of drug. Adding more water does not make more drug, it just spreads it thinner, so you draw a bigger number on the syringe for the same dose.

The only ratio printed on the vendor pages checked was 2 mg of each. Some sellers list a 10 mg vial without stating the split, and a vial whose label does not give the amount of each peptide cannot be dosed. Pick the option that matches your label, or enter your own.

Which vial do you have?

Pick your vial to see concentrations and a draw.

What you paid per vial
$
Used for cost per dose only.

Choose your mix

your own mL
units · —
Enter your own volume

Measuring the water1 mL = one full 100-unit syringe.

Your draw

Pick which vial you have above. A blend holds 2 separate compounds, so the draw depends on how many milligrams of each are in your vial.

What one draw delivers

The same arithmetic as the calculator, worked out for the vials vendors sell.

Dose anchored to Sermorelin, at the 0.2 to 0.5 mg per dose people commonly cite. Each table assumes one draw per dose. If you split it across more injections, divide the reading by the number of injections.

Vial
2 mg + 2 mg (4 mg total)
Sermorelin dose1 mL water2 mL water3 mL water
0.2 mg
10.0 units
  • Sermorelin 200 mcg
  • GHRP-6 200 mcg
20.0 units
  • Sermorelin 200 mcg
  • GHRP-6 200 mcg
30.0 units
  • Sermorelin 200 mcg
  • GHRP-6 200 mcg
0.5 mg
25.0 units
  • Sermorelin 500 mcg
  • GHRP-6 500 mcgabove its usual 0.3 mg
50.0 units
  • Sermorelin 500 mcg
  • GHRP-6 500 mcgabove its usual 0.3 mg
75.0 units
  • Sermorelin 500 mcg
  • GHRP-6 500 mcgabove its usual 0.3 mg

No published human study establishes a dose for this blend. The range is anchored to sermorelin, because a blend is one draw.

Sermorelin is usually cited at 200 to 500 mcg and GHRP-6 at 100 to 300 mcg. One draw from a 1:1 vial at the top of the sermorelin range delivers 500 mcg of GHRP-6, above its own range. The fixed ratio means you cannot raise one without raising the other.

What it costs

Sermorelin + GHRP-6 blend starts at $43.25 across 6 vendors, typically $8.80 – $21.63 per mg.

10 listings, last read Oct 24, 2026. Shipping and card fees are not included.

See all 10 listings →
07

How do you store it?

Before mixing, and after.

Dry powder in the freezer or fridge. Once mixed, fridge, and use within about a month.

Unmixed lyophilized Sermorelin + GHRP-6 blend keeps for a long time cold. Once you add water the clock starts: most reconstituted vials hold up for roughly 28 to 30 days at fridge temperature. Keep it out of light, and do not freeze it after mixing.

08

What are the side effects and cautions?

Known cautions and warnings for this compound.
Handling note

Some sellers list this blend as a 10 mg vial without printing how much of each peptide it holds. If your label does not give the amount of each, the dose cannot be worked out. Ask the vendor or do not use the vial.

Who should avoid it

Check these before anything else.

Stop and get help

These are emergencies. Seek care.
  • Signs of an allergic reaction
  • Persistent milky nipple discharge, a sign of raised prolactin from the GHRP-6

Common effects

Expected, and usually mild.
  • Injection-site reactions
  • Strong hunger, from the GHRP-6
  • Water retention
  • Tiredness after dosing
  • Flushing or warmth after injection
  • This is a blend, so the cautions of both peptides apply at once. It is also harder to tell which one caused a reaction.

Where this page says nothing is established, that means nobody has studied it, not that a compound is safe.

09

Is Sermorelin + GHRP-6 blend approved?

And where the numbers on this page come from.

No. Sermorelin + GHRP-6 blend is not approved for any use, anywhere. It is sold labeled for laboratory research only, and there is no legal route to buy it for human use.

  • Approval status
    Research only
  • Route
    Under the skin (subcutaneous)
  • Checked
    31 October 2026
  • Dose
    From community reports. No regulator or trial established this dose.
  • Vial size
    From what vendors typically list; not a recommendation.
  • Sources
    None traced yet.

What has happened recently

We have not yet written a full regulatory note for this compound. The status above is current as of the date shown.

Banned in drug-tested sport. Most research peptides are prohibited under WADA's S0 category, which covers any substance with no approval from any regulatory authority for human use. That means a compound can be banned without ever being named on the prohibited list. Check with your own anti-doping authority rather than assuming absence from the list means permitted.

You can compare this against the whole library, or read how to check a seller.

10

What else is like Sermorelin + GHRP-6 blend?

Others in Growth hormone peptides, side by side.

If you're weighing Sermorelin + GHRP-6 blend, it's worth reading Somapacitan (Sogroya), Somatostatin, and Somatrogon (Ngenla) in the same class.

Guides for this compound

Sources

No primary source has been traced for this compound yet. Treat everything on this page as unverified until one is. How we grade evidence