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NA-931_Dosage, benefits & legal status

Also known as Bioglutide, bioglutide, GLP-4, glp-4, GLP4, NA931, na 931

Published September 23, 2026

An experimental daily obesity capsule that has also become one of the most-faked names in the supply chain.

Weight lossIGF-1/GLP-1/GIP/glucagon agonistInvestigationalHigh-risk
DoseUp to 150 mg once daily in the phase 2 trial
FrequencyDaily
RouteBy mouth (oral capsule)
StatusInvestigational

Common vial size is what vendors typically sell, not a recommendation. Enter your own vial in the calculator.

See how this dose compares across the library →

01

What is NA-931?

Plain language first. The technical label stays, but it never stands alone.

Overview

A once-daily obesity capsule in clinical trials, claimed to hit four hormone receptors at once. The catch: it only exists as a capsule from its developer, and every injectable vial tested under this name has been a different compound.

The technical version

NA-931 (Bioglutide) is an orally active small-molecule described by Biomed Industries as a quadruple agonist of the IGF-1, GLP-1, GIP and glucagon receptors, in phase 2 and 3 development for obesity.

What it's used for

It is being developed for weight loss. The company's 13-week phase 2 in adults with obesity reported dose-dependent weight reduction up to 13.8% at 150 mg daily against placebo, presented at a conference and by press release, not yet in a peer-reviewed journal.

02

How does NA-931 work?

What it does in the body, and where.

NA-931 is described by its developer as a quadruple agonist: it is claimed to switch on four receptors at once, adding IGF-1 to the GLP-1, GIP and glucagon targets retatrutide hits.

  1. 01
    GLP-1, GIP and glucagon cover appetite and burn
    The same three levers as the injectable triple agonists: eat less, and spend more energy at rest.
  2. 02
    IGF-1 is the claimed fourth target
    The company says this protects muscle during weight loss. No body-composition data supporting that claim has been published.
  3. 03
    It is a capsule, not an injection
    An orally active small molecule taken once daily. Any vial sold for injection under this name is not the company's product.
Receptors
HITSIGF-1GLP-1GIP4

Hits 4 receptors at once.

03

What else is it used for?

Each group carries its own evidence level.

Approved means regulators have cleared it for that purpose. Investigational means it is in trials. Early research means it is being studied and is not established.

Weight loss

Investigational
  • Human trialThe company's 13-week phase 2 reported dose-dependent weight reduction up to 13.8% at 150 mg daily against placebo, presented at EASD in September 2025 and by press release.
  • Human trialA separate 28-day dose-escalation study in 74 participants (NCT06615700, published as a Diabetes conference abstract) reported dose-dependent weight reduction up to 6.4%, with up to 63% of treated participants losing at least 5% of body weight. Gastrointestinal events were reported as mild, and no nausea or vomiting was reported among treated subjects in that study.
  • Human trialPhase 3 trials of NA-931 alone and alongside semaglutide or tirzepatide are registered. No peer-reviewed results have been published.

What is actually in the vials

Investigational
  • lab-analysisRaw material sold as NA-931 tested by proton NMR and mass spectrometry came back as cyclo(Pro-Gly), a 154 dalton cyclic dipeptide also called NA-831, one digit apart in the developer's own naming.
  • lab-analysisA product sold as Bioglutide tested as a blend of retatrutide and cagrilintide; a third sample was [D-Lys3]-GHRP-6. Three samples, three different compounds.
Often left out

The 13.8% weight loss figure is the company-reported top-dose result at 150 mg daily, announced by press release and conference presentation, not a peer-reviewed average. And "GLP-4" is a seller label, not a real receptor class; the developer has never sold NA-931 as an injectable.

NA-931 vial rendering
Compound field notes

At a glance

Four things to know about NA-931

01

Evidence

Investigational

02

Category

Weight loss and metabolic

03

Common vial

Varies

04

Half-life

Not established

04

How much, and do you cycle it?

The range, and whether you take breaks.

Up to 150 mg once daily in the phase 2 trial, daily. Not cycled.

05

What does it cost?

Typical dose and cost, in plain numbers.

NA-931 is not injected

It is taken by mouth (oral capsule). Top dose in the company's 13-week phase 2, given as a once-daily capsule. No injectable dose exists; vials sold as NA-931 are grey-market products that have tested as other compounds.

Cost per month
Cost per dose
Typical dose
150 mg–150 mg / dayTrial dose
06

How do you store it?

Before mixing, and after.

Dry powder in the freezer or fridge. Once mixed, fridge, and use within about a month.

Unmixed lyophilized NA-931 keeps for a long time cold. Once you add water the clock starts: most reconstituted vials hold up for roughly 28 to 30 days at fridge temperature. Keep it out of light, and do not freeze it after mixing.

07

What are the side effects and cautions?

Known cautions and warnings for this compound.

Who should avoid it

Check these before anything else.
  • Not legally available outside clinical trials, so no prescriber is assessing whether it suits you
  • Pregnancy, or trying to become pregnant

Stop and get help

These are emergencies. Seek care.
  • Signs of an allergic reaction
  • Any severe or persistent symptom, because with grey-market vials the contents are unknown and testing has found three different compounds sold under this name

Common effects

Expected, and usually mild.
  • The company describes the phase 2 as well tolerated without publishing the detail
  • No independent safety data exists, so the real-world effect profile is unknown

Where this page says nothing is established, that means nobody has studied it, not that a compound is safe.

08

Is NA-931 approved?

And where the numbers on this page come from.

No. NA-931 is not approved anywhere and is currently in company-run clinical trials. There is no legal route to obtain it outside a trial.

What has happened recently

Not approved in any country. Phase 3 trials (120 mg once daily, alone and combined with oral semaglutide) were announced at the ADA meeting in June 2026, but no results have been published in a peer-reviewed journal. NA-931 has never been sold as an injectable by its developer; any vial labelled NA-931, Bioglutide or GLP-4 is an unregulated grey-market product, and independent tests of such vials have found a different compound every time.

Guides for this compound

Sources

  • Biomed Industries, NA-931 phase 3 press release(2026)
    Describes NA-931 as an orally active small-molecule quadruple receptor agonist targeting IGF-1, GLP-1, GIP and glucagon; reports 13-week phase 2 weight reduction up to 13.8% at 150 mg daily against placebo. Company statement about its own unapproved product.
  • ClinicalTrials.gov, NCT06564753 (phase 2)(2026)
    A 13-week randomised, double-blind, placebo-controlled study in adults with obesity or overweight with a comorbidity; sponsor Biomed Industries.
  • ClinicalTrials.gov, NCT06615700 and NCT06732245(2026)
    A phase 1 study of 74 participants taking NA-931 capsules, and a later trial of NA-931 alongside tirzepatide.
  • Diabetes 2025;74(Suppl 1):143-OR (ADA abstract, NCT06615700)(2025)
    28-day randomised, double-blind, placebo-controlled dose-escalation study in 74 overweight or obese participants: dose-dependent weight reduction up to 6.4%, up to 63% achieving at least 5% weight loss, and only mild gastrointestinal adverse events reported.
  • Biomed Industries, EASD 2025 press release(2025)
    Records that the company's chief executive presented the phase 2 results at the EASD annual meeting in Vienna in September 2025.
  • Aus Aminos, Bioglutide investigation(2025)
    A long investigation arguing that NA-931 does not exist and that the company's data were fabricated. The author sells peptides, so this is an interested party, and the allegations have not been tested by a court or regulator.
  • Independent analytical testing reports(2026)
    Material sold as NA-931 by a Chinese supplier tested at NuMega Resonance Labs came back as cyclo(Pro-Gly), mass 154 daltons. An earlier Bioglutide product tested at Janoshik was a retatrutide and cagrilintide blend; a third sample was [D-Lys3]-GHRP-6. Not peer-reviewed; the underlying lab reports should be requested before relying on the detail.

Last reviewed 23 September 2026