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HMG (Menotropin)_

Also known as menotropin, Menopur, human menopausal gonadotropin

A fertility hormone shot that drives sperm or egg production.

FertilityGonadotropin (FSH + LH)Clinical use
Common vial size75 IU
Dose75 up to 150 IU per dose (start low, increase slowly)
FrequencySeveral per week
RouteUnder the skin or into muscle
StatusPrescription
CycledGiven within a treatment cycle, roughly 7 to 12 days, then stopped

Common vial size is what vendors typically sell, not a recommendation. Enter your own vial in the calculator.

01

What is HMG (Menotropin)?

Plain language first. The technical label stays, but it never stands alone.

Overview

HMG (menotropin) is a fertility medication containing both FSH and LH, the two pituitary hormones that drive egg and sperm production. In plain terms: it supplies those signals directly to stimulate fertility, used in fertility treatment and sometimes with testosterone therapy.

What it's used for

A fertility hormone shot that supplies the two signals needed to drive sperm or egg production, used in fertility treatment and sometimes with testosterone therapy.

02

How does HMG (Menotropin) work?

What it does in the body, and where.

HMG is purified from the urine of postmenopausal women, whose pituitaries produce large amounts of FSH and LH. It supplies both.

  1. 01
    It provides FSH and LH together
    FSH drives sperm and follicle development; LH drives testosterone and ovulation. Most fertility drugs supply only one.
  2. 02
    It acts directly on the gonads
    Bypassing both the brain and the pituitary.
  3. 03
    It is a purified biological product
    Composition and the exact FSH-to-LH ratio vary by preparation, which matters clinically.
  4. 04
    Overstimulation is a real risk
    In women, ovarian hyperstimulation syndrome, which is why fertility treatment is monitored with scans and blood tests rather than dosed by protocol alone.
Where it acts
TestesOvaries

Where this compound is thought to act.

03

What else is it used for?

Each use below carries its own evidence level. Approved means regulators have cleared it for that purpose. Investigational means it is in trials. Early research means it is being studied and is not established.

  • Growing multiple follicles during fertility treatment, which is its approved useFDA-approved
  • Supporting sperm production in men, used off-labelClinical use
04

How much, and do you cycle it?

The range, and whether you take breaks.

75 up to 150 IU per dose (start low, increase slowly), several per week. Given within a treatment cycle, roughly 7 to 12 days, then stoppedFDA label

Dosed daily through an ovarian stimulation cycle and adjusted by monitoring, then stopped. The cycle is the treatment, not a break from it.

Compare cycling across compounds →

05

How do I dose and price it?

Enter your vial and your dose. Pick a mix. We show the draw and the cost.

The vial holds a fixed amount of drug. Adding more water does not make more drug, it just spreads it thinner, so you draw a bigger number on the syringe for the same dose.

Your vial size (mg)
Printed on the vial.
What you paid per vial
$
Used for cost per dose only.
Your dose (mg)
Commonly referenced range: 75 up to 150 IU per dose (start low, increase slowly)Clinical use

Choose your mix

your own mL
units · —
Enter your own volume

Measuring the water1 mL = one full 100-unit syringe.

Your draw

2.7 / 100 units
2.7 units is a very small line to read, so a small slip is a large error. A larger water volume above spreads the same dose across more units.
06

How do you store it?

Before mixing, and after.

Dry powder in the freezer or fridge. Once mixed, fridge, and use within about a month.

Unmixed lyophilized HMG (Menotropin) keeps for a long time cold. Once you add water the clock starts: most reconstituted vials hold up for roughly 28 to 30 days at fridge temperature. Keep it out of light, and do not freeze it after mixing.

07

What are the side effects and cautions?

Known cautions and warnings for this compound.

Who should avoid it

Check these before anything else.
  • Pregnancy, where it can harm a developing baby
  • A previous allergic reaction to this class
  • Ovaries that have stopped working, shown by a high FSH level
  • Untreated thyroid or adrenal problems
  • Tumours of the breast or reproductive organs that respond to hormones
  • Pituitary or hypothalamic tumours
  • Unexplained abnormal vaginal bleeding
  • Ovarian cysts or enlarged ovaries not caused by PCOS

Stop and get help

These are emergencies. Seek care.
  • Severe pelvic pain with bloating, rapid weight gain, nausea, or shortness of breath, which can signal ovarian overstimulation and needs emergency care
  • Sudden severe one-sided pelvic pain, which can signal a twisted ovary
  • Swelling, pain, or warmth in a leg, or chest pain and breathlessness, which can signal a blood clot
  • Signs of an allergic reaction such as face or throat swelling, hives, or trouble breathing

Common effects

Expected, and usually mild.
  • Abdominal cramps, bloating, and pain
  • Headache
  • Injection-site pain and inflammation
  • Pelvic pain
  • Breast tenderness

Where this page says nothing is established, that means nobody has studied it, not that a compound is safe.

08

Is HMG (Menotropin) approved?

And where the numbers on this page come from.
Clinical use

Yes. Approved for clinical use.

A regulator has cleared it for specific uses in a clinical setting.

  • DoseFrom product labeling and clinical guidelines.
  • Vial sizeFrom what vendors typically list; not a recommendation.
  • Reviewed22 July 2026
10

What these words mean

Show glossary +
Titrate
Starting at a low dose and increasing it slowly over time so your body adjusts and side effects stay mild.
Subcutaneous
An injection just under the skin, into the fat layer, usually with a short, thin insulin needle.
Intramuscular (IM)
An injection into a muscle, using a longer needle.
Reconstitution
Mixing a powdered peptide with liquid (bacteriostatic water) so it can be drawn into a syringe.
Bacteriostatic water
Sterile water with a tiny amount of preservative, used to mix powdered peptides.
Concentration
How strong the mixed peptide is, in milligrams per milliliter (mg/mL). More water makes it weaker; less water makes it stronger.
Units (on the syringe)
The marks on an insulin syringe. 100 units equals 1 mL. They measure how much liquid you draw, not the dose in milligrams.
mcg and mg
Units of dose. 1 milligram (mg) equals 1,000 micrograms (mcg).
GLP-1
A natural gut hormone that lowers appetite and blood sugar. Drugs that copy it, like semaglutide, are used for weight loss.
Growth hormone secretagogue
A compound that nudges your body to release more of its own growth hormone, rather than injecting the hormone itself.
Half-life
How long a compound stays active in your body. A longer half-life means you inject less often.
Peptide vs small molecule
A peptide is a short chain of amino acids. A few items here (like MK-677 or methylene blue) are small molecules, not true peptides, but people use them the same way.
Research only
No approved dose or use in people. Sold for research and not reviewed by the FDA for safety or quality.
Investigational
Still being tested in clinical trials and not yet approved or legally sold for general use.
Banned in drug-tested sport
Prohibited by the World Anti-Doping Agency (WADA); using it can disqualify a competing athlete.

Last reviewed 22 July 2026