Sexual and hormonal

PT-141 (bremelanotide) is a melanocortin receptor agonist, a cyclic peptide that acts on the MC4R receptor in the brain. In plain terms: it raises sexual desire through brain signaling rather than blood flow, which is different from how erection drugs work. It is FDA-approved for low libido in women.

Kisspeptin is a natural brain peptide that sits at the very top of the reproductive hormone chain, switching on the neurons that release GnRH. In plain terms: it kick-starts your body's own sex-hormone production, which is why it is studied for libido and fertility, with a gentler feel than PT-141.

Gonadorelin is synthetic GnRH, the hormone your brain uses to tell the pituitary to make testosterone and fertility hormones. In plain terms: it prompts your own hormone production, often used alongside testosterone therapy to keep the testicles active. Because it clears fast, it needs frequent dosing.

HCG (human chorionic gonadotropin) is a hormone that mimics LH, the signal that tells the testicles to make testosterone and sperm. In plain terms: it keeps the testicles switched on, commonly used alongside testosterone therapy or for fertility.

HMG (menotropin) is a fertility medication containing both FSH and LH, the two pituitary hormones that drive egg and sperm production. In plain terms: it supplies those signals directly to stimulate fertility, used in fertility treatment and sometimes with testosterone therapy.

Oxytocin is a natural 9-amino-acid hormone made in the brain, released during touch, closeness, and childbirth. In plain terms: known as the 'bonding hormone,' it is used as a nasal spray or tablet for connection, mood, and sometimes libido, with subtle, short-lived effects.