5-Amino-1MQ is a nnmt inhibitor (small molecule) used for weight loss. 5-Amino-1MQ is a small molecule, not a peptide, that blocks an enzyme called NNMT which helps fat cells store fat. In plain terms: by taking the brakes off cellular metabolism, it is studied for burning fat and boosting energy, though human data is very limited.

How much water do I add to 5-Amino-1MQ?

You can reconstitute 5-Amino-1MQ with 0.5, 1, or 2 mL of bacteriostatic water. Each option produces a different concentration and syringe draw for the same dose. Use the calculator to see which is easiest to measure.

What does 5-Amino-1MQ cost per dose?

Cost per dose depends on vial size, price paid, and your dose. Enter your vendor's price in the 5-Amino-1MQ calculator to see cost per dose and monthly cost.

What is the reference dose for 5-Amino-1MQ?

The commonly referenced range is 0.15 up to 5 mg per day injected (the capsule dose is far higher, see below), taken daily, cycled. This is reference information, not a recommendation. Talk to a licensed clinician.

What are the side effects of 5-Amino-1MQ?

Reported side effects of 5-Amino-1MQ include: This is early research with very little human data, so its safety in people is not well known.. Severity and frequency vary by person and dose.

Who should not take 5-Amino-1MQ?

5-Amino-1MQ is generally not appropriate for: No human safety data exists at all; Pregnancy. Talk to a licensed clinician before starting.

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Decoding

5-Amino-1MQ_Dosage, benefits & legal status

Also known as 5-amino-1-methylquinolinium

By the Peptide Decoding Editorial Team

Published July 22, 2026 · Updated August 14, 2026

A capsule studied for speeding up metabolism and burning fat.

Weight lossNNMT inhibitor (small molecule)Research only

InFat loss without GLP-1

Dose0.15 up to 5 mg per day injected (the capsule dose is far higher, see below)

FrequencyDaily, cycled

RouteBy mouth or under the skin

StatusResearch only

MixYour choice, calculate it

CycledCommonly cycled

Common vial size is what vendors typically sell, not a recommendation. Enter your own vial in the calculator.

What is 5-Amino-1MQ?

Plain language first. The technical label stays, but it never stands alone.

Overview

It takes the brakes off how cells burn fuel. That is why it is studied for fat loss and energy. Human data is very limited.

The technical version

5-Amino-1MQ is a small molecule, not a peptide, that blocks an enzyme called NNMT which helps fat cells store fat.

What it's used for

People take it hoping to speed up metabolism and burn fat, usually in cycles. Human data is very limited, so results are uncertain.

How does 5-Amino-1MQ work?

What it does in the body, and where.

5-Amino-1MQ is a small molecule, not a peptide, that blocks an enzyme fat cells use to keep storing fat.

01
It inhibits NNMT
An enzyme that is unusually abundant in fat tissue and appears to help fat cells hold onto what they store.
02
In mice, fat cells shrank and metabolism rose
The animal results are the entire basis for the interest in it.
03
There is essentially no human data
No completed clinical trial establishes that any of this happens in people, or what a safe dose would be.

Pathway

A schematic of the compound's mechanism, not a diagnostic image.

What else is it used for?

Each use below carries its own evidence level. Approved means regulators have cleared it for that purpose. Investigational means it is in trials. Early research means it is being studied and is not established.

Speeding up metabolism and burning fatResearch only
Preserving muscle while losing fatResearch only

The published record

Research index

Records indexed for 5-Amino-1MQ

3 in humans, 3 of them original studies.

Browse the records

In animalsPro

In the labPro

ReviewsPro

Senior author sharePro

Counted from Europe PMC indexing, not read by a person. Human means indexed under humans, which includes reviews and work on human cells. Original studies exclude reviews and lab work on human cells.Last updated 11 September 2026.

Compound field notes

At a glance

Four things to know about 5-Amino-1MQ

Evidence

Research only

How much, and do you cycle it?

The range, and whether you take breaks.

0.15 up to 5 mg per day injected (the capsule dose is far higher, see below), daily, cycled. Commonly cycledCommunity practice

Cycled by convention rather than to a tested schedule. No published study establishes a block length or a break length for this one.

Compare this against the whole library →

How long does it stay in the body?

The half-life, and where the figure comes from.

Not establishedCommunity practice

The 5 to 8 hour figure is usually credited to a 2019 University of Vienna study. No such study can be found.

Not yet traced to a primary source.

You can compare this against the whole library to see where it sits.

How do I dose and price it?

Enter your vial and your dose. Pick a mix. We show the draw and the cost.

The vial holds a fixed amount of drug. Adding more water does not make more drug, it just spreads it thinner, so you draw a bigger number on the syringe for the same dose.

Your vial size (mg)

Printed on the vial.

What you paid per vial

Used for cost per dose only.

Your dose (mg)

Commonly referenced range: 0.15 up to 5 mg per day injected (the capsule dose is far higher, see below)Community practice

Choose your mix

0.5 mL water0.8units · 20 mg/mL

Half a 100-unit syringe

1 mL water1.5units · 10 mg/mL

One full 100-unit syringe

Easiest

2 mL water3units · 5 mg/mL

Two full 100-unit syringes

your own mL

units · —

Enter your own volume

Measuring the water1 mL = one full 100-unit syringe.

Your draw

3 / 100 units

3 units is a very small line to read, so a small slip is a large error. A larger water volume above spreads the same dose across more units.

Full calculator with reorder date →Read a syringe →

By capsule instead: 50 to 150 mg per day. Capsule dose. Most research-context use of this compound is oral.

What it costs

5-Amino-1MQ starts at $19.00 across 49 vendors, typically $1.30 – $9.00 per mg.

81 listings, last read Sep 5, 2026. Shipping and card fees are not included.

See all 81 listings →

How do you store it?

Before mixing, and after.

Dry powder in the freezer or fridge. Once mixed, fridge, and use within about a month.

Unmixed lyophilized 5-Amino-1MQ keeps for a long time cold. Once you add water the clock starts: most reconstituted vials hold up for roughly 28 to 30 days at fridge temperature. Keep it out of light, and do not freeze it after mixing.

What are the side effects and cautions?

Known cautions and warnings for this compound.

Handling note

Check which form you have before you calculate anything. Capsules are dosed at 50 to 150 mg a day. That same amount injected would be 10 to 30 mL of liquid, and a subcutaneous injection tops out around 2 to 5 mL per site, so the capsule number cannot be used with a syringe. Injected figures run from 150 mcg to 5 mg a day instead. If your calculator is asking for a draw larger than a full syringe, you have almost certainly entered the capsule dose.

Who should avoid it

Check these before anything else.

No human safety data exists at all
Pregnancy

Stop and get help

These are emergencies. Seek care.

Anything unusual, since there is no known safety profile
Signs of an allergic reaction such as face or throat swelling, hives, or trouble breathing

Common effects

Expected, and usually mild.

Unknown in humans. It has only been studied in rodents

Where this page says nothing is established, that means nobody has studied it, not that a compound is safe.

Is 5-Amino-1MQ approved?

And where the numbers on this page come from.

No. 5-Amino-1MQ is not approved for any use, anywhere. It is sold labelled for laboratory research only, and there is no legal route to buy it for human use.

Approval status
Research only
Route
By mouth or under the skin
Checked
September 2026

What has happened recently

We have not yet written a full regulatory note for this compound. The status above is current as of the date shown.

You can compare this against the whole library, or read how to check a seller.

DoseFrom research and community reports. No regulator has reviewed this dose.
Vial sizeFrom what vendors typically list; not a recommendation.
Sources
Neelakantan et al., NNMT inhibitors reverse high fat diet-induced obesity in mice, Biochemical Pharmacology NNMT as a therapeutic target for metabolic syndrome, Frontiers in Pharmacology
Reviewed8 September 2026

What else is like 5-Amino-1MQ?

Others in Fat loss without GLP-1, side by side.

If you're weighing 5-Amino-1MQ, it's worth reading SLU-PP-332, Setmelanotide (Imcivree), and GHRP-6 in the same class.

YOU ARE HERE

5A1MQSmall molecule

5-Amino-1MQ

A capsule studied for speeding up metabolism and burning fat.

Research only

Dose: 0.15 up to 5 mg per day injected (the capsule dose is far higher, see below)
How often: Daily, cycled

SLU

SLU-PP-332

An experimental 'exercise in a molecule,' very early and unproven in people.

Research only

Dose: Research only
How often: Cycled

SETMEL

Setmelanotide (Imcivree)

An approved daily shot for rare genetic forms of obesity.

FDA-approved

Dose: 2 up to 3 mg per day (start low, increase slowly)
How often: Daily

GHRP-6

A growth-hormone shot that also triggers strong hunger, used for bulking.

Research only

Dose: 0.1 up to 0.3 mg per dose (start low, increase slowly)
How often: 1-3x daily

See other fat loss without glp-1

Guides for this compound

How to Reconstitute a Peptide
Mix peptide powder with bacteriostatic water, step by step.
How to Read an Insulin Syringe
Read the units, convert to millilitres, and draw the exact dose.
mcg vs mg: The Peptide Dosing Mistake to Avoid
Your vial says mg and your protocol says mcg. Here is the conversion and how to check it.
Why Does My Peptide Injection Itch or Welt
Injection-site irritation, a histamine reaction, or a true allergy, and how to tell them apart.
How to Read a Peptide COA
What the purity number does and does not tell you, and how to spot an edited report.

Sources

Neelakantan et al., NNMT inhibitors reverse high fat diet-induced obesity in mice, Biochemical Pharmacology(2018)
The pivotal study. Diet-induced obese mice given a potent NNMT inhibitor lost body weight and white adipose mass with no change in food intake. Mice, not people.
NNMT as a therapeutic target for metabolic syndrome, Frontiers in Pharmacology(2024)
Review placing 5-amino-1MQ among NNMT inhibitors. No NNMT inhibitor has reached regulatory approval for any indication, and no human trial of 5-amino-1MQ appears in the literature.

Last reviewed 8 September 2026

Beyond these, 3 records are indexed. Browse the records