Tuftsin_Dosage, benefits & legal status
Also known as TKPR, Thr-Lys-Pro-Arg, tuftsin peptide
A four-amino-acid immune peptide from the 1970s, and the parent of Selank.
Common vial size is what vendors typically sell, not a recommendation. Enter your own vial in the calculator.
What is Tuftsin?
Plain language first. The technical label stays, but it never stands alone.Overview
A four-amino-acid immune peptide from the 1970s. Selank was built from it precisely because tuftsin itself falls apart too fast to be useful.
Tuftsin (Thr-Lys-Pro-Arg), a tetrapeptide derived from the CH2 domain of the immunoglobulin G heavy chain, described as a phagocytosis-stimulating factor. Parent molecule of the Russian-registered anxiolytic Selank. No modern controlled human trial of tuftsin administration has been published outside its original research era.
What it's used for
An immune peptide researched for stimulating phagocytes, and the molecule Selank was designed from.
How does Tuftsin work?
What it does in the body, and where.Tuftsin is one of the older compounds in this library and the connection to Selank is the most useful thing about it.
- 01It comes from an antibodyTuftsin is a tetrapeptide released from the heavy chain of immunoglobulin G, named after Tufts University where it was described in the 1970s.
- 02Its documented action is on phagocytesReported to stimulate macrophages and neutrophils to engulf and destroy bacteria, which is the basis of the immune claims made for it.
- 03Selank is tuftsin with a tailThe Russian anxiolytic Selank, which this library covers, is a tuftsin analog with additional residues added for stability. Selank's evidence belongs to Selank and does not transfer back to the parent.
What else is it used for?
Each use below carries its own evidence level. Approved means regulators have cleared it for that purpose. Investigational means it is in trials. Early research means it is being studied and is not established.
- Stimulating phagocytes, the cells that engulf bacteriaEarly research
- Immune support generallyResearch only
- As the parent molecule of SelankClinical use
The published record
Papers and trials about Tuftsin
165 papers tagged human · 100 not reviews or lab · 3 clinical trial publications
Furthest stage reached: Published trials only, 3 clinical trial publications, no phased trial registered
Counted from Europe PMC indexing, not read by a person; a human tag can land on reviews, commentary or lab papers; clinical trial publications is the narrower count. 442 papers and 0 trials indexed in detail.
At a glance
Four things to know about Tuftsin
How much, and do you cycle it?
The range, and whether you take breaks.Research only, not established. Not established No range
No schedule has been studied for this compound in people.
Nothing publishedNo figure
No reliable half-life for administered tuftsin in people was located.
You can compare this against the whole library to see where it sits.
How do I dose and price it?
Enter your vial and your dose. Pick a mix. We show the draw and the cost.The vial holds a fixed amount of drug. Adding more water does not make more drug, it just spreads it thinner, so you draw a bigger number on the syringe for the same dose.
Choose your mix
Measuring the water1 mL = one full 100-unit syringe.
How do you store it?
Before mixing, and after.Dry powder in the freezer or fridge. Once mixed, fridge, and use within about a month.
Unmixed lyophilized Tuftsin keeps for a long time cold. Once you add water the clock starts: most reconstituted vials hold up for roughly 28 to 30 days at fridge temperature. Keep it out of light, and do not freeze it after mixing.
What are the side effects and cautions?
Known cautions and warnings for this compound.Who should avoid it
- Pregnancy or breastfeeding
- An autoimmune condition, where stimulating immune cells is a poor idea without advice
- Immunosuppressant medication, including after a transplant
- Anyone who wants established safety data, because none exists for this compound in humans
Stop and get help
- Signs of an allergic reaction, including spreading hives, facial or throat swelling, or trouble breathing
- Redness, heat, or pus at the injection site, which can signal infection
- Anything unusual, since there is no known safety profile to compare it against
Common effects
- Unknown. No study has recorded what this commonly causes in people
- Redness, soreness, or a small bump at the injection site
Where this page says nothing is established, that means nobody has studied it, not that a compound is safe.
Is Tuftsin approved?
And where the numbers on this page come from.No. Tuftsin is not approved for any use, anywhere. It is sold labeled for laboratory research only, and there is no legal route to buy it for human use.
- Approval statusResearch only
- RouteUnder the skin (subcutaneous)
- Checked24 August 2026
- DoseFrom community reports. No regulator or trial established this dose.
- Vial sizeFrom what vendors typically list; not a recommendation.
- SourcesNone traced yet.
What has happened recently
We have not yet written a full regulatory note for this compound. The status above is current as of the date shown.
You can compare this against the whole library, or read how to check a seller.
What else is like Tuftsin?
Others in Immune support, side by side.If you're weighing Tuftsin, it's worth reading Thymosin Alpha-1, Glutathione, and LL-37 in the same class.
A four-amino-acid immune peptide from the 1970s, and the parent of Selank.
- Dose
- Research only
- How often
- Not established
A well-studied shot that tunes up the immune system.
- Dose
- 1.6 mg per dose
- How often
- 2x per week
Your body's master antioxidant, taken for glowing skin and detox support.
- Dose
- 250 up to 1000 mg per day
- How often
- Daily (oral)
A natural germ-fighting peptide for stubborn infections and wound healing.
- Dose
- 0.1 up to 0.5 mg per dose (start low, increase slowly)
- How often
- Daily, short courses
Guides for this compound
- How to Reconstitute a Peptide
Mix peptide powder with bacteriostatic water, step by step.
- How to Read an Insulin Syringe
Read the units, convert to millilitres, and draw the exact dose.
- mcg vs mg: The Peptide Dosing Mistake to Avoid
Your vial says mg and your protocol says mcg. Here is the conversion and how to check it.
- How to Read a Peptide COA
What the purity number does and does not tell you, and how to spot an edited report.
- How to Vet a Peptide Vendor
Independent COAs, HPLC purity, and the red flags that mean walk away.
Sources
No primary source has been traced for this compound yet. Treat everything on this page as unverified until one is. How we grade evidence
Beyond these, 442 records are indexed. Browse the records