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Thymogen_Dosage, benefits & legal status

Also known as Glu-Trp, EW, Thymagen, glutamyl-tryptophan

Published July 22, 2026 · Updated August 24, 2026

A short immune bioregulator taken in courses, with thin evidence.

ImmuneBioregulator dipeptideResearch only
Common vial size10 mg
DoseVaries (course-based)
FrequencyCourses
RouteUnder the skin or as a nasal spray
StatusResearch only
CycledCourses of 10 to 20 days, repeated two or three times a year

Common vial size is what vendors typically sell, not a recommendation. Enter your own vial in the calculator.

01

What is Thymogen?

Plain language first. The technical label stays, but it never stands alone.

Overview

It is taken in courses to support immune function, but there is very little real human research behind it.

The technical version

Thymogen is a 2-amino-acid thymus 'bioregulator' from the Russian Khavinson family.

What it's used for

A short immune bioregulator taken in courses to support immune function.

02

How does Thymogen work?

What it does in the body, and where.

Thymogen is two amino acids, glutamic acid and tryptophan, from the thymus branch of the Khavinson family.

  1. 01
    The claim is immune support
    Given in short courses, sometimes nasally.
  2. 02
    Evidence is Russian-language and unreplicated
    No independent Western trial.
03

What else is it used for?

Each use below carries its own evidence level. Approved means regulators have cleared it for that purpose. Investigational means it is in trials. Early research means it is being studied and is not established.

  • Supporting immune function, taken in coursesResearch only

The published record

Research index

110

Records indexed for Thymogen

49 in humans, 40 of them original studies.

1 registered trials, 0 with posted results.

Browse the records

In animalsPro
In the labPro
ReviewsPro
Senior author sharePro

Counted from Europe PMC indexing, not read by a person. Human means indexed under humans, which includes reviews and work on human cells. Original studies exclude reviews and lab work on human cells.Last updated 12 September 2026.

Thymogen vial rendering
Compound field notes

At a glance

Four things to know about Thymogen

01

Evidence

Research only

02

Category

Immune support

03

Common vial

10 mg

04

Half-life

Nothing published

04

How much, and do you cycle it?

The range, and whether you take breaks.

Varies (course-based), courses. Courses of 10 to 20 days, repeated two or three times a yearCommunity practice

The course structure is how the Khavinson protocols specify these and how they are sold. No trial has compared course dosing against continuous use, or established how long the gap between courses should be.

Compare this against the whole library →

05

How long does it stay in the body?

The half-life, and where the figure comes from.

Nothing publishedNo figure

No half-life has ever been published for any of the Russian bioregulator peptides, in people or in animals. The research behind them, mostly from one group in St Petersburg, measures effects on tissue, gene activity and lifespan. None of it measures how long the peptide stays in the body.

You can compare this against the whole library to see where it sits.

06

How do I dose and price it?

Enter your vial and your dose. Pick a mix. We show the draw and the cost.

The vial holds a fixed amount of drug. Adding more water does not make more drug, it just spreads it thinner, so you draw a bigger number on the syringe for the same dose.

Your vial size (mg)
Printed on the vial.
What you paid per vial
$
Used for cost per dose only.
Your dose (mg)
Commonly referenced range: Varies (course-based)No range

Choose your mix

your own mL
units · —
Enter your own volume

Measuring the water1 mL = one full 100-unit syringe.

Your draw

0 / 100 units
What it costs

Thymogen starts at $29.00 across 6 vendors, typically $2.95 – $5.95 per mg.

6 listings, last read Sep 5, 2026. Shipping and card fees are not included.

See all 6 listings →
07

How do you store it?

Before mixing, and after.

Fridge after opening. Use within about 30 days.

Store sealed Thymogen in the fridge. Once opened, keep it upright in the fridge and plan to finish it inside roughly 30 days. Keep it out of light and do not freeze the liquid.

08

What are the side effects and cautions?

Known cautions and warnings for this compound.

Who should avoid it

Check these before anything else.
  • No formal Western contraindications established
  • Pregnancy
  • Immunosuppressive therapy, as a precaution

Stop and get help

These are emergencies. Seek care.
  • Signs of an allergic reaction

Common effects

Expected, and usually mild.
  • Limited published safety data from Russian clinical use
  • No Western controlled trials exist

Where this page says nothing is established, that means nobody has studied it, not that a compound is safe.

09

Is Thymogen approved?

And where the numbers on this page come from.

No. Thymogen is not approved for any use, anywhere. It is sold labelled for laboratory research only, and there is no legal route to buy it for human use.

  • Approval status
    Research only
  • Route
    Under the skin or as a nasal spray
  • Checked
    July 2026

What has happened recently

We have not yet written a full regulatory note for this compound. The status above is current as of the date shown.

You can compare this against the whole library, or read how to check a seller.


Guides for this compound

Sources

  • Avolio et al., Peptides Regulating Proliferative Activity and Inflammatory Pathways in the Monocyte/Macrophage THP-1 Cell Line (International Journal of Molecular Sciences 23:3607)(2022)
    Thymogen is the dipeptide Glu-Trp, separated from the thymus extract Thymalin by chromatography, and in this experiment it was the strongest performer on one specific measure: it cut the adhesion of monocytes to inflamed endothelial cells almost to the level of uninflamed control, and it was the most effective of the five at reducing IL-17 release. It also increased proliferative signalling and reduced TNF and IL-6. Two limits belong on this alongside the result. Everything here is a human leukemia cell line incubated overnight at 100 ng/mL, with no animal or human data, and Khavinson and two colleagues from his Saint Petersburg institute are co-authors, so this is not the independent replication this family of compounds still lacks.

Last reviewed 22 July 2026

Beyond these, 110 records are indexed. Browse the records