Pancragen_Dosage, benefits & legal status
Also known as Pancragen, KEDW, Lys-Glu-Asp-Trp
A lab-made 4 amino acid peptide aimed at the pancreas.
Common vial size is what vendors typically sell, not a recommendation. Enter your own vial in the calculator.
What is Pancragen?
Plain language first. The technical label stays, but it never stands alone.Overview
It is marketed for pancreas function and blood sugar as you age. There is very little real human research behind it.
Pancragen is a 4-amino-acid 'bioregulator' from the Russian Khavinson family.
What it's used for
Marketed for pancreas function and blood sugar with age. Taken in short courses.
How does Pancragen work?
What it does in the body, and where.Pancragen is 4 amino acids long, written KEDW.
- 01The claim is pancreas and blood sugar supportThe longest of the family at four amino acids ending in tryptophan.
- 02No citable human evidenceNo blood sugar or insulin data for this peptide appears in the English-language literature.
What else is it used for?
Each use below carries its own evidence level. Approved means regulators have cleared it for that purpose. Investigational means it is in trials. Early research means it is being studied and is not established.
- Supporting the pancreas with age, which is the claim made for itResearch only
- The lab-made counterpart to the pancreas extract sold as Suprefort.Early research
The published record
Papers and trials about Pancragen
4 papers tagged human · 1 not reviews or lab · 0 clinical trial publications
Furthest stage reached: No clinical trial on record

At a glance
Four things to know about Pancragen
Evidence
Category
Weight loss and metabolic
Common vial
10 mg
Half-life
Nothing published
How much, and do you cycle it?
The range, and whether you take breaks.Research only, daily, in 10-20 day courses. Daily for 10 to 20 days, then a long break Community practice
The whole family is used in short courses repeated a few times a year. That pattern comes from Russian practice, not from a trial comparing it against anything else.
Nothing publishedNo figure
No half-life has ever been published for any of the Russian bioregulator peptides, in people or in animals. The research behind them, mostly from one group in St Petersburg, measures effects on tissue, gene activity and lifespan. None of it measures how long the peptide stays in the body.
You can compare this against the whole library to see where it sits.
How do I dose and price it?
Enter your vial and your dose. Pick a mix. We show the draw and the cost.The vial holds a fixed amount of drug. Adding more water does not make more drug, it just spreads it thinner, so you draw a bigger number on the syringe for the same dose.
Choose your mix
Measuring the water1 mL = one full 100-unit syringe.
Pancragen starts at $34.00 across 11 vendors, typically $2.75 – $4.75 per mg.
12 listings, last read Oct 10, 2026. Shipping and card fees are not included.
How do you store it?
Before mixing, and after.Dry powder in the freezer or fridge. Once mixed, fridge, and use within about a month.
Unmixed lyophilized Pancragen keeps for a long time cold. Once you add water the clock starts: most reconstituted vials hold up for roughly 28 to 30 days at fridge temperature. Keep it out of light, and do not freeze it after mixing.
What are the side effects and cautions?
Known cautions and warnings for this compound.Sold beside Suprefort, the animal-tissue extract aimed at the same organ. Different products, and the evidence does not transfer between them.
Who should avoid it
- Pregnancy or breastfeeding
- Active cancer, as a precaution given the claimed effect on gene activity
- Known allergy to it
Stop and get help
- Signs of an allergic reaction such as face or throat swelling, hives, or trouble breathing
- Redness, heat, or pus where it was injected
Common effects
- Injection-site reactions
- Generally reported as well tolerated
- No controlled human trial has recorded side effects
Where this page says nothing is established, that means nobody has studied it, not that a compound is safe.
Is Pancragen approved?
And where the numbers on this page come from.No. Pancragen is not approved for any use, anywhere. It is sold labeled for laboratory research only, and there is no legal route to buy it for human use.
- Approval statusResearch only
- RouteUnder the skin, or by mouth
- Checked14 August 2026
- DoseFrom community reports. No regulator or trial established this dose.
- Vial sizeFrom what vendors typically list; not a recommendation.
- SourcesNone traced yet.
What has happened recently
We have not yet written a full regulatory note for this compound. The status above is current as of the date shown.
You can compare this against the whole library, or read how to check a seller.
If you're weighing Pancragen, it's worth reading Lipo-C (MIC blend), GW501516 (Cardarine), and ATX-304 (O-304) in the same class.
A lab-made 4 amino acid peptide aimed at the pancreas.
- Dose
- Research only
- How often
- Daily, in 10-20 day courses
A compounded fat-loss shot with no fixed formula and no approved version.
- Dose
- No standard dose. The formula changes between pharmacies
- How often
- Usually weekly
A discontinued drug whose development stopped over cancer in multiple organs.
- Dose
- 2.5 up to 10 mg per day
- How often
- Once daily in the trials
An exercise mimetic that got through a phase 2a trial and then went quiet.
- Dose
- 400 mg per day
- How often
- Once daily in the trial
Guides for this compound
- How to Reconstitute a Peptide
Mix peptide powder with bacteriostatic water, step by step.
- How to Read an Insulin Syringe
Read the units, convert to millilitres, and draw the exact dose.
- mcg vs mg: The Peptide Dosing Mistake to Avoid
Your vial says mg and your protocol says mcg. Here is the conversion and how to check it.
- Why Does My Peptide Injection Itch or Welt
Injection-site irritation, a histamine reaction, or a true allergy, and how to tell them apart.
- How to Read a Peptide COA
What the purity number does and does not tell you, and how to spot an edited report.
Sources
No primary source has been traced for this compound yet. Treat everything on this page as unverified until one is. How we grade evidence
Beyond these, 20 records are indexed. Browse the records
