P7C3_Dosage, benefits & legal status
Also known as P7C3-A20, aminopropyl carbazole
A neuroprotective molecule from a mouse screen. Never given to a person.
Common vial size is what vendors typically sell, not a recommendation. Enter your own vial in the calculator.
What is P7C3?
Plain language first. The technical label stays, but it never stands alone.Overview
A small molecule that keeps young brain cells alive in animals by boosting NAD. No human trial has ever been run.
P7C3 is an aminopropyl carbazole that binds and activates NAMPT, the rate-limiting enzyme in the NAD salvage pathway, producing proneurogenic and neuroprotective effects across rodent models of Parkinson's, ALS, traumatic brain injury, stroke and depression.
What it's used for
Sold for brain protection and cognition. Everything published is in cells, rodents and one monkey study.
How does P7C3 work?
What it does in the body, and where.P7C3 was named after where it sat on a screening plate, which tells you how it was found.
- 01A screen in live miceResearchers looked for anything that increased the survival of newborn hippocampal neurons. The third compound in the seventh pool worked.
- 02The target turned out to be NAMPTThe enzyme that limits how fast cells make NAD, which is why the effect looks like protection rather than growth.
- 03It stopped at monkeysA 38-week study in rhesus monkeys extended the rodent findings. No human trial has followed.
A schematic of the compound's mechanism, not a diagnostic image.
What else is it used for?
Each use below carries its own evidence level. Approved means regulators have cleared it for that purpose. Investigational means it is in trials. Early research means it is being studied and is not established.
- Protecting brain cells after injuryResearch only
- Neurodegenerative disease modelsResearch only
- Mood and cognition claimsResearch only
The published record
Papers about P7C3
Searched: P7C3, P7C3-A20.
21 papers tagged human · 12 not reviews or lab · 0 clinical trial publications
How the compound was given: 6 applied to skin · 16 injected · 5 by mouth or rectal · 69 route not stated in the abstract
Read from each paper's indexing terms and abstract, by rule. A paper that mentions a cream studied a cream, not necessarily the product being sold.
Furthest stage reached: No clinical trial on record
Counted from Europe PMC indexing, not read by a person; a human tag can land on reviews, commentary or lab papers; clinical trial publications is the narrower count. A preprint and its journal version count once.
At a glance
Four things to know about P7C3
Evidence
Category
Brain, mood and sleep
Common vial
10 mg
Half-life
Nothing published in humans
How much, and do you cycle it?
The range, and whether you take breaks.Research only, no established pattern. No established pattern No range
No published human study establishes a schedule.
Nothing published in humansNo figure
You can compare this against the whole library to see where it sits.
How do I dose and price it?
Enter your vial and your dose. Pick a mix. We show the draw and the cost.The vial holds a fixed amount of drug. Adding more water does not make more drug, it just spreads it thinner, so you draw a bigger number on the syringe for the same dose.
No flat reference range is recorded for this compound. The calculator only does the math on the dose you enter.
Choose your mix
Measuring the water1 mL = one full 100-unit syringe.
How do you store it?
Before mixing, and after.Dry powder in the freezer or fridge. Once mixed, fridge, and use within about a month.
Unmixed lyophilized P7C3 keeps for a long time cold. Once you add water the clock starts: most reconstituted vials hold up for roughly 28 to 30 days at fridge temperature. Keep it out of light, and do not freeze it after mixing.
What are the side effects and cautions?
Known cautions and warnings for this compound.Who should avoid it
- No human safety data exists at all
- Pregnancy
Stop and get help
- Anything unusual, since there is no known safety profile
- Signs of an allergic reaction such as face or throat swelling, hives, or trouble breathing
Common effects
- Unknown in humans. Studied in rodents and one nonhuman primate study
Where this page says nothing is established, that means nobody has studied it, not that a compound is safe.
Is P7C3 approved?
And where the numbers on this page come from.No. P7C3 is not approved for any use, anywhere. It is sold labeled for laboratory research only, and there is no legal route to buy it for human use.
- Approval statusResearch only
- RouteBy mouth in the animal studies
- Checked24 September 2026
- DoseNo dose has been established in people.
- Vial sizeFrom what vendors typically list; not a recommendation.
- Sources
What has happened recently
Not approved anywhere. No registered human trial.
You can compare this against the whole library, or read how to check a seller.
What else is like P7C3?
Others in Brain, mood and sleep, side by side.If you're weighing P7C3, it's worth reading Substance P, Trofinetide (Daybue), and Ziconotide in the same class.
A neuroprotective molecule from a mouse screen. Never given to a person.
- Dose
- Research only
- How often
- No established pattern
Approved medicine blocks it. One paper suggests putting it on your face.
- Dose
- No established dose
- How often
- Not applicable
An approved oral treatment for Rett syndrome, built from the first three amino acids of IGF-1 with one methyl group added.
- Dose
- 5,000 to 12,000 mg twice daily by weight (label)
- How often
- Twice daily
The FDA-approved cone-snail peptide for severe chronic pain, delivered only into the spinal fluid.
- Dose
- 2.4 up to 19.2 mcg per day by continuous pump (label)
- How often
- Continuous infusion
Guides for this compound
- mcg vs mg: The Peptide Dosing Mistake to Avoid
Your vial says mg and your protocol says mcg. Here is the conversion and how to check it.
- How to Read a Peptide COA
What the purity number does and does not tell you, and how to spot an edited report.
- How to Vet a Peptide Vendor
Independent COAs, HPLC purity, and the red flags that mean walk away.
Sources
- Wang G, et al. P7C3 neuroprotective chemicals function by activating the rate-limiting enzyme in NAD salvage. Cell(2014)Identified NAMPT as the target, explaining the neuroprotection seen in rodent models.
Beyond these, 93 records are indexed. Browse the records