Cortagen is a short bioregulator peptide. B7-33 is a relaxin analog.
Bioregulators are taken in short courses and rest almost entirely on Russian research that has not been replicated elsewhere.
| Comparison | Cortagen AEDP · Ala-Glu-Asp-Pro | B7-33 relaxin B-chain analog · B7 33 |
|---|---|---|
| How it works | How it works Cortagen is a short bioregulator based on a brain-tissue peptide, used for nerve recovery in the Khavinson protocols. | How it works Relaxin does two things through the same receptor, and B7-33 was built to keep one of them. |
| What it is | A bioregulator taken in courses for nerve and tissue recovery, with thin evidence. | A single-chain piece of relaxin, built to keep the anti-scarring effect and drop the tumour risk. |
| Status | Research only | Research only |
| Typical dose | — | — |
| How often | Courses | Varies |
| Stays active | Nothing published | About 6 minutes in serum |
| Dose comes from | No established range | No established range |
| Cycled? | Courses of 10 to 20 days, repeated two or three times a year Community practice | No established pattern No established range |
| What it does | ||
| Drug class | Bioregulator peptide | Relaxin analog |
| Used for | A bioregulator taken in courses for nerve and tissue recovery and healthy aging. | Studied in animals for scarring in the heart, lungs and kidneys. Sold online for recovery and tissue repair on the strength of that animal work. |
| Receptors hit | — | — |
| Numbers | ||
| Full dose line | Varies (course-based) | Research only |
| Why that cycle | The course structure is how the Khavinson protocols specify these and how they are sold. No trial has compared course dosing against continuous use, or established how long the gap between courses should be. | No published human study establishes a schedule. |
| Weight / effect | Not measured in a trial | Not measured in a trial |
| Chain length | 4 residues | Not disclosed |
| Common vial | 10 mg | 10 mg |
| Before you start | ||
| Route | Under the skin (subcutaneous) | Under the skin (subcutaneous) |
| Do not use if | Pregnancy or breastfeeding Any prescription medicine you take regularly, without checking for interactions first Anyone who wants established safety data, because none exists for this compound in humans | Pregnancy or breastfeeding Any active cancer, since the parent hormone has a tumour-growth signal Any use, given no human trial exists |
What separates them
Proof behind the dose. Every dose here comes from community practice. Not one is backed by a published human study, which is worth knowing before you read the numbers as if they were equivalent.
What doesn't differ: They are both taken the same way (under the skin) and aimed at the same thing (recovery / nerve). Neither has a measured effect size from a published trial, so there is no number to rank them on.
What people actually report
Cortagen
- Little human evidence.
- Spreading hives, swelling of the face or throat, or trouble breathing, which can happen with any injection and is a medical emergency
- Redness, heat, or pus at the injection site, which can signal infection
B7-33
- No human safety data exists.
- Everything known comes from cell work and animal models.
- Any allergic reaction
- Any unexpected symptom
Side effects are what users and trials report most often, not a complete list. Anything sudden, spreading, or breathing-related is an emergency regardless of which compound caused it.
People also compare
This comparison does not cover cost, long-term safety, or how you personally will respond. Effect figures come from separate trials in different populations and are not always directly comparable to each other. Nothing here is medical advice or a recommendation to use any of these. Talk to a clinician about your own situation.