Bonothyrk_Dosage, benefits & legal status
Also known as A-21, peptide complex A-21, parathyroid peptide bioregulator, Bonothyrk lingual, BioParathyroid
An animal-tissue extract for the parathyroid glands, sold as capsules.
Common vial size is what vendors typically sell, not a recommendation. Enter your own vial in the calculator.
What is Bonothyrk?
Plain language first. The technical label stays, but it never stands alone.Overview
A capsule made from calf parathyroid glands, sold for calcium balance and bone strength. The bone density claim uses a timescale too short for a scan to measure.
Cytomax peptide fraction A-21, extracted from bovine parathyroid tissue of animals under twelve months. Labeled daily intake is 20 mg of peptide complex A-21 in two capsules. Proposed mechanism is tissue-specific modulation of gene expression in parathyroid chief cells. No controlled human efficacy data has been published outside the originating Russian research program.
What it's used for
An oral tissue extract marketed for parathyroid function, calcium balance and bone strength.
How does Bonothyrk work?
What it does in the body, and where.Bonothyrk is a mixture of small peptides pulled from parathyroid tissue, usually from calves under a year old.
- 01Drawn from calf parathyroid glandsA Cytomax, extracted from the parathyroid glands of animals under twelve months. Product labeling gives a daily amount of 20 mg of peptide complex A-21 across two capsules.
- 02The claim is calcium and phosphate balanceThe parathyroid glands control calcium and phosphate levels, which is real physiology. The proposal that an oral extract adjusts that control has not been demonstrated in people.
- 03It has no synthetic counterpart hereVentfort has Vesugen and Testoluten has Testagen. No Cytogen parathyroid peptide exists in this library, so there is no synthetic version to compare the evidence against.
What else is it used for?
Each use below carries its own evidence level. Approved means regulators have cleared it for that purpose. Investigational means it is in trials. Early research means it is being studied and is not established.
- Supporting parathyroid function and calcium balance, taken orallyResearch only
- Osteoporosis and low bone density, in Russian clinical practicenone
- Overactive and underactive parathyroid glandsnone
- Added to bone and joint courses alongside Sigumir and Ventfortnone
The published record
0
Papers and trials about Bonothyrk
Europe PMC was searched on 12 October 2026 and returned nothing.
Counted from Europe PMC indexing, not read by a person.
At a glance
Four things to know about Bonothyrk
Evidence
Category
Healing and recovery
Common vial
Varies
Half-life
Nothing published
How much, and do you cycle it?
The range, and whether you take breaks.Research only, daily, in 10-30 day courses. Daily for 10 to 30 days, then a long break, repeated a few times a year Community practice
The course pattern comes from Russian practice. Suppliers describe the effect as lasting six to twelve months after a course, which is a claim from the sellers rather than a measured result.
Nothing publishedNo figure
No half-life has ever been published for any of the Russian bioregulator peptides, in people or in animals. The research behind them, mostly from one group in St Petersburg, measures effects on tissue, gene activity and lifespan. None of it measures how long the peptide stays in the body.
You can compare this against the whole library to see where it sits.
What does it cost?
Typical dose and cost, in plain numbers.Bonothyrk is not injected
It is taken by mouth (oral). Sold as capsules, so there is nothing to reconstitute and the calculator does not apply. No dose has been established in a published human study.
How do you store it?
Before mixing, and after.Room temperature. Cool, dry, out of light.
Bonothyrk is taken as a pill or capsule. Keep it in its original container at room temperature, away from heat, humidity, and direct sun. No fridge or mixing needed. Check the expiration date on the bottle.
What are the side effects and cautions?
Known cautions and warnings for this compound.Who should avoid it
- Pregnancy or breastfeeding
- A known allergy to bovine products
- A diagnosed parathyroid or calcium disorder, where an unstudied extract is not a substitute for treatment
- Anyone taking calcium, vitamin D or bone medication, without checking for interactions first
Stop and get help
- Any allergic reaction
- Muscle cramps, tingling around the mouth or in the fingers, which can signal a calcium problem
- Bone pain or a fracture from a minor knock
Common effects
- No side effects are reported by the manufacturer.
- Nobody has run the kind of monitored trial that would find them, so the absence is a gap rather than a finding.
Where this page says nothing is established, that means nobody has studied it, not that a compound is safe.
Is Bonothyrk approved?
And where the numbers on this page come from.No. Bonothyrk is not approved for any use, anywhere. It is sold labeled for laboratory research only, and there is no legal route to buy it for human use.
- Approval statusResearch only
- RouteBy mouth (oral)
- Checked24 August 2026
- DoseFrom community reports. No regulator or trial established this dose.
- Vial sizeFrom what vendors typically list; not a recommendation.
- SourcesNone traced yet.
What has happened recently
Not approved for any medical use in the US, Europe or Australia. Sold as a dietary supplement in some markets and as a research item in others. Registration in Russia does not carry over.
You can compare this against the whole library, or read how to check a seller.
What else is like Bonothyrk?
Others in Taken without a needle, side by side.If you're weighing Bonothyrk, it's worth reading Chelohart, Chitomur, and Danuglipron in the same class.
An animal-tissue extract for the parathyroid glands, sold as capsules.
- Dose
- Research only
- How often
- Daily, in 10-30 day courses
An animal-tissue extract for the heart muscle, sold as capsules.
- Dose
- Research only
- How often
- Daily, in 10-30 day courses
An animal-tissue extract for the bladder, sold as capsules.
- Dose
- Research only
- How often
- Daily, in 10-30 day courses
An experimental weight-loss pill whose development was stopped over a liver-injury signal.
- Dose
- 40 up to 200 mg per dose
- How often
- Daily
Guides for this compound
- mcg vs mg: The Peptide Dosing Mistake to Avoid
Your vial says mg and your protocol says mcg. Here is the conversion and how to check it.
- How to Read a Peptide COA
What the purity number does and does not tell you, and how to spot an edited report.
- How to Vet a Peptide Vendor
Independent COAs, HPLC purity, and the red flags that mean walk away.
Sources
No primary source has been traced for this compound yet. Treat everything on this page as unverified until one is. How we grade evidence