Semax is a acth(4-10) peptide. Adamax is a disputed.
| Comparison | Semax ACTH 4-10 | Adamax ADAMAX · Semax analog |
|---|---|---|
| How it works | How it works Semax is seven amino acids based on a fragment of ACTH, a brain-signalling hormone, with the hormonal part removed. It is a nasal spray, and it is a registered medicine in Russia. | How it works The honest starting point is that nobody selling this agrees on what it is. |
| What it is | A peptide used for sharper focus, memory, and mental clarity. | A product name that different vendors use for completely different things. |
| Status | Research only | Research only |
| Typical dose | 0.2–0.6 mg per day | — |
| How often | 1-2x daily | No established schedule |
| Stays active | Minutes | Nothing published in humans |
| Dose comes from | Published human study | No established range |
| Cycled? | Taken in courses, usually 10 to 14 days, with breaks between Community practice | No established pattern No established range |
| What it does | ||
| Drug class | ACTH(4-10) peptide | Disputed |
| Used for | Sharpens focus, memory, and mental clarity by raising a brain-growth signal. It works within about half an hour and is used in Russia for stroke recovery and attention. | Marketed for cognition and focus by some sellers, and for growth hormone release and recovery by others. |
| Receptors hit | — | — |
| Numbers | ||
| Full dose line | 0.2 up to 0.6 mg per day | Research only |
| Why that cycle | The Russian clinical literature uses course dosing rather than continuous use, and users report the effect fading if it is taken every day without a break. No controlled study has compared courses against continuous use. | No published human study establishes a schedule. |
| Weight / effect | Not measured in a trial | Not measured in a trial |
| Chain length | 7 residues | Not disclosed |
| Common vial | 30 mg | 10 mg |
| Before you start | ||
| Route | Nasal spray, or injected under the skin | Nasal spray, or injected under the skin |
| Do not use if | No formal contraindications established outside Russia Pregnancy | Any use, given that the contents are not defined Pregnancy or breastfeeding |
What separates them
Proof behind the dose. Semax has a dose from a published human study. Adamax has no established dose range at all.
What doesn't differ: They are both taken the same way (nasal spray, or injected under the skin) and aimed at the same thing (focus & brain). Neither has a measured effect size from a published trial, so there is no number to rank them on.
What people actually report
Semax
- Mostly mild nasal irritation or occasional headache, reported from nasal use.
- No dependence has been reported.
- Effects from injection have not been studied.
- No serious adverse events have been reported at studied doses
- Signs of an allergic reaction
Adamax
- Unknown, because the compound is not defined.
- Effects reported by users cannot be attributed to any specific molecule.
- Any unexpected effect, since you cannot know what produced it
Side effects are what users and trials report most often, not a complete list. Anything sudden, spreading, or breathing-related is an emergency regardless of which compound caused it.
People also compare
This comparison does not cover cost, long-term safety, or how you personally will respond. Effect figures come from separate trials in different populations and are not always directly comparable to each other. Nothing here is medical advice or a recommendation to use any of these. Talk to a clinician about your own situation.